Gene NameYPR019W (CDC54) (MCM4, HCD21)
SGD DescriptionEssential helicase component of heterohexameric MCM2-7 complexes which bind pre-replication complexes on DNA and melt the DNA prior to replication; accumulates in the nucleus in G1; homolog of S. pombe Cdc21p
Biological Process• Cell proliferation • Cell cycle • DNA repair • DNA replication • Nucleobase, nucleoside, nucleotide and nucleic acid metabolism
Molecular Function• ATP binding activity • ATPase activity • DNA binding activity • Enzyme activity • Hydrolase activity • Nucleotide binding activity
Cellular Component• Nucleus • Nucleoplasm • Replication fork • Cytoplasm • Cytosol