Gene NameYPL262W (FUM1)
SGD DescriptionFumarase, converts fumaric acid to L-malic acid in the TCA cycle; cytosolic and mitochondrial distribution determined by the N-terminal targeting sequence, protein conformation, and status of glyoxylate shunt; phosphorylated in mitochondria
Biological Process• cellular process • cellular physiological process • cellular metabolism • cellular catabolism • cofactor catabolism • coenzyme catabolism • acetyl-CoA catabolism • tricarboxylic acid cycle • cofactor metabolism • coenzyme metabolism • acetyl-CoA metabolism • generation of precursor metabolites and energy • energy derivation by oxidation of organic compounds • cellular respiration • aerobic respiration • main pathways of carbohydrate metabolism • physiological process • metabolism • catabolism • macromolecule metabolism • carbohydrate metabolism • cellular carbohydrate metabolism • primary metabolism • tricarboxylic acid cycle intermediate metabolism • fumarate metabolism • organic acid metabolism • carboxylic acid metabolism
Molecular Function• catalytic activity • lyase activity • carbon-oxygen lyase activity • hydro-lyase activity • fumarate hydratase activity
Cellular Component• cell • intracellular • cytoplasm • mitochondrion • mitochondrial lumen • mitochondrial matrix • intracellular organelle • intracellular membrane-bound organelle • membrane-enclosed lumen • organelle lumen • organelle • membrane-bound organelle • cytosol