Gene NameYOR136W (IDH2)
SGD DescriptionSubunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which catalyzes the oxidation of isocitrate to alpha-ketoglutarate in the TCA cycle; phosphorylated
Biological Process• cellular process • cellular physiological process • cellular metabolism • cellular catabolism • cofactor catabolism • coenzyme catabolism • acetyl-CoA catabolism • tricarboxylic acid cycle • cofactor metabolism • coenzyme metabolism • acetyl-CoA metabolism • generation of precursor metabolites and energy • energy derivation by oxidation of organic compounds • cellular respiration • aerobic respiration • main pathways of carbohydrate metabolism • physiological process • metabolism • catabolism • macromolecule metabolism • carbohydrate metabolism • cellular carbohydrate metabolism • primary metabolism • tricarboxylic acid cycle intermediate metabolism • isocitrate metabolism • organic acid metabolism • carboxylic acid metabolism • amine metabolism • amine biosynthesis • amino acid biosynthesis • glutamine family amino acid biosynthesis • glutamate biosynthesis • amino acid metabolism • glutamine family amino acid metabolism • glutamate metabolism • amino acid and derivative metabolism • cellular biosynthesis • nitrogen compound biosynthesis • biosynthesis • nitrogen compound metabolism
Molecular Function• catalytic activity • oxidoreductase activity • oxidoreductase activity, acting on CH-OH group of donors • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor • isocitrate dehydrogenase activity • isocitrate dehydrogenase (NAD+) activity
Cellular Component• cell • intracellular • cytoplasm • mitochondrion • intracellular organelle • intracellular membrane-bound organelle • organelle • membrane-bound organelle • mitochondrial lumen • mitochondrial matrix • membrane-enclosed lumen • organelle lumen