Gene NameYOR123C (LEO1)
SGD DescriptionComponent of the Paf1 complex; which associates with RNA polymerase II and is involved in histone methylation; plays a role in regulating Ty1 transposition; involved in transcription elongation as demonstrated by the G-less-based run-on (GLRO) assay
Biological Process• cellular process • cellular physiological process • cellular metabolism • nucleobase, nucleoside, nucleotide and nucleic acid metabolism • transcription • transcription, DNA-dependent • transcription from RNA polymerase II promoter • physiological process • metabolism • primary metabolism • RNA elongation • RNA elongation from RNA polymerase II promoter • cell organization and biogenesis • organelle organization and biogenesis • chromosome organization and biogenesis • chromosome organization and biogenesis (sensu Eukaryota) • establishment and/or maintenance of chromatin architecture • chromatin modification • covalent chromatin modification • histone modification • histone methylation • cellular macromolecule metabolism • cellular protein metabolism • protein modification • protein amino acid alkylation • protein amino acid methylation • DNA metabolism • DNA packaging • macromolecule metabolism • biopolymer metabolism • biopolymer modification • biopolymer methylation • protein metabolism
Molecular Function• transcription regulator activity • transcriptional elongation regulator activity • RNA polymerase II transcription elongation factor activity
Cellular Component• cell • intracellular • intracellular organelle • intracellular membrane-bound organelle • nucleus • organelle • membrane-bound organelle • nuclear lumen • nucleoplasm • transcription elongation factor complex • membrane-enclosed lumen • organelle lumen • protein complex • DNA-directed RNA polymerase II, holoenzyme • Cdc73/Paf1 complex