Gene NameYOR005C (DNL4)
SGD DescriptionDNA ligase required for nonhomologous end-joining (NHEJ), forms stable heterodimer with required cofactor Lif1p, interacts with Nej1p; involved in meiosis, not essential for vegetative growth
Biological Process• cellular process • cellular physiological process • cellular metabolism • nucleobase, nucleoside, nucleotide and nucleic acid metabolism • DNA metabolism • DNA repair • double-strand break repair • double-strand break repair via nonhomologous end-joining • non-recombinational repair • physiological process • metabolism • macromolecule metabolism • biopolymer metabolism • primary metabolism • response to stimulus • response to endogenous stimulus • response to DNA damage stimulus • response to stress
Molecular Function• catalytic activity • ligase activity • ligase activity, forming phosphoric ester bonds • DNA ligase activity • DNA ligase (ATP) activity
Cellular Component• cell • intracellular • intracellular organelle • intracellular membrane-bound organelle • nucleus • organelle • membrane-bound organelle