Gene NameYOR001W (RRP6)
SGD DescriptionNuclear exosome exonuclease component; has 3'-5' exonuclease activity; involved in RNA processing, maturation, surveillance, degradation, tethering, and export; has similarity to E. coli RNase D and to human PM-Sc1 100 (EXOSC10); mutant displays reduced transcription elongation in the G-less-based run-on (GLRO) assay
Biological Process• cellular process • cellular physiological process • cell organization and biogenesis • cytoplasm organization and biogenesis • ribosome biogenesis and assembly • ribosome biogenesis • rRNA processing • 35S primary transcript processing • organelle organization and biogenesis • cellular metabolism • nucleobase, nucleoside, nucleotide and nucleic acid metabolism • RNA metabolism • RNA processing • rRNA metabolism • physiological process • metabolism • macromolecule metabolism • biopolymer metabolism • primary metabolism • cellular catabolism • cellular macromolecule catabolism • RNA catabolism • mRNA catabolism • mRNA metabolism • catabolism • macromolecule catabolism
Molecular Function• catalytic activity • hydrolase activity • hydrolase activity, acting on ester bonds • nuclease activity • exonuclease activity • 3'-5' exonuclease activity • 3'-5'-exoribonuclease activity • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters • exoribonuclease activity, producing 5'-phosphomonoesters • exoribonuclease activity • ribonuclease activity
Cellular Component• cell • intracellular • exosome (RNase complex) • nuclear exosome (RNase complex) • intracellular organelle • intracellular membrane-bound organelle • nucleus • organelle • membrane-bound organelle • protein complex