Gene NameYOL004W (SIN3) (CPE1, RPD1, SDI1, GAM2, SDS16, UME4)
SGD DescriptionComponent of the Sin3p-Rpd3p histone deacetylase complex, involved in transcriptional repression and activation of diverse processes, including mating-type switching and meiosis; involved in the maintenance of chromosomal integrity
Biological Process• cellular process • cellular physiological process • cell organization and biogenesis • organelle organization and biogenesis • chromosome organization and biogenesis • chromosome organization and biogenesis (sensu Eukaryota) • establishment and/or maintenance of chromatin architecture • chromatin assembly or disassembly • chromatin assembly • heterochromatin formation • chromatin silencing • chromatin silencing at rDNA • chromatin modification • chromatin remodeling • cellular metabolism • nucleobase, nucleoside, nucleotide and nucleic acid metabolism • DNA metabolism • DNA packaging • gene silencing • regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism • negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism • negative regulation of transcription • negative regulation of transcription, DNA-dependent • regulation of transcription • regulation of transcription, DNA-dependent • transcription • transcription, DNA-dependent • regulation of cellular metabolism • negative regulation of cellular metabolism • regulation of cellular physiological process • negative regulation of cellular physiological process • regulation of cellular process • negative regulation of cellular process • development • regulation of gene expression, epigenetic • negative regulation of gene expression, epigenetic • physiological process • metabolism • macromolecule metabolism • biopolymer metabolism • primary metabolism • regulation of metabolism • negative regulation of metabolism • regulation of physiological process • negative regulation of physiological process • regulation of biological process • negative regulation of biological process • telomere maintenance • DNA repair • double-strand break repair • double-strand break repair via nonhomologous end-joining • non-recombinational repair • response to stimulus • response to endogenous stimulus • response to DNA damage stimulus • response to stress • chromatin silencing at telomere • telomeric heterochromatin formation • regulation of transcription from RNA polymerase II promoter • transcription from RNA polymerase II promoter • chromatin silencing at silent mating-type cassette
Molecular Function• catalytic activity • hydrolase activity • deacetylase activity • histone deacetylase activity • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
Cellular Component• cell • intracellular • intracellular organelle • intracellular membrane-bound organelle • nucleus • nuclear lumen • nucleoplasm • transcription factor complex • histone deacetylase complex • membrane-enclosed lumen • organelle lumen • organelle • membrane-bound organelle • protein complex • Sin3 complex