Gene NameYNL021W (HDA1)
SGD DescriptionPutative catalytic subunit of a class II histone deacetylase complex that also contains Hda2p and Hda3p; Hda1p interacts with the Hda2p-Hda3p subcomplex to form an active tetramer; deletion increases histone H2B, H3 and H4 acetylation
Biological Process• cellular process • cellular physiological process • cell death • cell aging • progressive alteration of chromatin during cell aging • progressive alteration of chromatin during replicative cell aging • loss of chromatin silencing during replicative cell aging • replicative cell aging • cell organization and biogenesis • organelle organization and biogenesis • chromosome organization and biogenesis • chromosome organization and biogenesis (sensu Eukaryota) • establishment and/or maintenance of chromatin architecture • chromatin modification • chromatin remodeling • loss of chromatin silencing • cellular metabolism • nucleobase, nucleoside, nucleotide and nucleic acid metabolism • DNA metabolism • DNA packaging • regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism • positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism • positive regulation of transcription • positive regulation of transcription, DNA-dependent • regulation of transcription • regulation of transcription, DNA-dependent • transcription • transcription, DNA-dependent • regulation of cellular metabolism • positive regulation of cellular metabolism • regulation of cellular physiological process • positive regulation of cellular physiological process • regulation of cellular process • positive regulation of cellular process • development • aging • regulation of gene expression, epigenetic • positive regulation of gene expression, epigenetic • physiological process • death • metabolism • macromolecule metabolism • biopolymer metabolism • primary metabolism • regulation of metabolism • positive regulation of metabolism • regulation of physiological process • positive regulation of physiological process • regulation of biological process • positive regulation of biological process • cellular macromolecule metabolism • cellular protein metabolism • protein modification • protein amino acid deacetylation • biopolymer modification • protein metabolism
Molecular Function• catalytic activity • hydrolase activity • deacetylase activity • histone deacetylase activity • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
Cellular Component• cell • intracellular • intracellular organelle • intracellular membrane-bound organelle • nucleus • nuclear lumen • nucleoplasm • transcription factor complex • histone deacetylase complex • membrane-enclosed lumen • organelle lumen • organelle • membrane-bound organelle • protein complex