Gene NameYKL145W (RPT1) (CIM5, YTA3)
SGD DescriptionOne of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for optimal CDC20 transcription; interacts with Rpn12p and Ubr1p; mutant has aneuploidy tolerance
Biological Process• cellular process • cellular physiological process • cellular metabolism • cellular catabolism • cellular macromolecule catabolism • cellular protein catabolism • proteolysis during cellular protein catabolism • modification-dependent protein catabolism • ubiquitin-dependent protein catabolism • cellular macromolecule metabolism • cellular protein metabolism • proteolysis • physiological process • metabolism • catabolism • macromolecule catabolism • biopolymer catabolism • protein catabolism • macromolecule metabolism • biopolymer metabolism • protein metabolism • primary metabolism
Molecular Function• catalytic activity • hydrolase activity • peptidase activity • endopeptidase activity • hydrolase activity, acting on acid anhydrides • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • pyrophosphatase activity • nucleoside-triphosphatase activity • ATPase activity
Cellular Component• cell • intracellular • proteasome complex (sensu Eukaryota) • proteasome regulatory particle (sensu Eukaryota) • proteasome regulatory particle, base subcomplex (sensu Eukaryota) • protein complex