Gene NameYIL094C (LYS12) (LYS11, LYS10)
SGD DescriptionHomo-isocitrate dehydrogenase, an NAD-linked mitochondrial enzyme required for the fourth step in the biosynthesis of lysine, in which homo-isocitrate is oxidatively decarboxylated to alpha-ketoadipate
Biological Process• cellular process • cellular physiological process • cellular metabolism • amine metabolism • amine biosynthesis • amino acid biosynthesis • aspartate family amino acid biosynthesis • lysine biosynthesis • amino acid metabolism • aspartate family amino acid metabolism • lysine metabolism • amino acid and derivative metabolism • cellular biosynthesis • nitrogen compound biosynthesis • organic acid metabolism • carboxylic acid metabolism • physiological process • metabolism • biosynthesis • nitrogen compound metabolism • primary metabolism
Molecular Function• catalytic activity • oxidoreductase activity • oxidoreductase activity, acting on CH-OH group of donors • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor • homoisocitrate dehydrogenase activity
Cellular Component• cell • intracellular • cytoplasm • mitochondrion • intracellular organelle • intracellular membrane-bound organelle • organelle • membrane-bound organelle