Gene NameYGR129W (SYF2)
SGD DescriptionMember of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; isy1 syf2 cells have defective spindles activiating cell cycle arrest
Biological Process• cellular process • cellular physiological process • cellular metabolism • nucleobase, nucleoside, nucleotide and nucleic acid metabolism • RNA metabolism • mRNA metabolism • mRNA processing • nuclear mRNA splicing, via spliceosome • RNA processing • RNA splicing • RNA splicing, via transesterification reactions • RNA splicing, via transesterification reactions with bulged adenosine as nucleophile • physiological process • metabolism • macromolecule metabolism • biopolymer metabolism • primary metabolism • cell cycle
Molecular Function• binding • nucleic acid binding • RNA binding • RNA splicing factor activity, transesterification mechanism
Cellular Component• cell • intracellular • intracellular organelle • intracellular membrane-bound organelle • nucleus • spliceosome complex • ribonucleoprotein complex • organelle • membrane-bound organelle • protein complex