Gene NameYEL062W (NPR2)
SGD DescriptionSubunit of SEA (Seh1-associated), Npr2/3, and Iml1p complexes; Npr2/3 complex mediates downregulation of TORC1 activity upon amino acid limitation; SEA complex is a coatomer-related complex that associates dynamically with the vacuole; Iml1p complex (Iml1p-Npr2p-Npr3p) is required for non-nitrogen-starvation (NNS)-induced autophagy; Iml1p interacts primarily with phosphorylated Npr2p; homolog of human NPRL2; target of Grr1p; required for growth on urea and proline
Biological Process• cellular process • cellular physiological process • transport • amine transport • amino acid transport • L-amino acid transport • L-proline transport • neutral amino acid transport • organic acid transport • carboxylic acid transport • physiological process • localization • establishment of localization • urea transport
Molecular Function• transporter activity • auxiliary transport protein activity • channel regulator activity
Cellular Component• cellular component unknown