Gene NameYDR113C (PDS1)
SGD DescriptionSecurin, inhibits anaphase by binding separin Esp1p; blocks cyclin destruction and mitotic exit, essential for meiotic progression and mitotic cell cycle arrest; localization is cell-cycle dependent and regulated by Cdc28p phosphorylation
Biological Process• cellular process • cellular physiological process • cell cycle • M phase • M phase of mitotic cell cycle • mitosis • mitotic sister chromatid segregation • mitotic cell cycle • chromosome segregation • sister chromatid segregation • physiological process • cellular metabolism • nucleobase, nucleoside, nucleotide and nucleic acid metabolism • DNA metabolism • DNA recombination • recombinational repair • DNA repair • metabolism • macromolecule metabolism • biopolymer metabolism • primary metabolism • response to stimulus • response to endogenous stimulus • response to DNA damage stimulus • response to stress • cell organization and biogenesis • cellular localization • establishment of cellular localization • intracellular transport • intracellular protein transport • protein targeting • protein import into nucleus • nuclear transport • nuclear import • nucleocytoplasmic transport • transport • protein transport • protein import • localization • establishment of localization • establishment of protein localization • protein localization
Molecular Function• binding • protein binding
Cellular Component• cell • intracellular • intracellular organelle • intracellular membrane-bound organelle • nucleus • organelle • membrane-bound organelle • cytoskeleton • microtubule cytoskeleton • spindle • intracellular non-membrane-bound organelle • non-membrane-bound organelle