Gene NameYDL165W (CDC36) (DNA19, NOT2)
SGD DescriptionComponent of the CCR4-NOT complex, which has multiple roles in regulating mRNA levels including regulation of transcription and destabilizing mRNAs by deadenylation; basal transcription factor
Biological Process• cellular process • cellular physiological process • cell cycle • regulation of cell cycle • regulation of progression through cell cycle • regulation of cellular physiological process • regulation of cellular process • physiological process • regulation of physiological process • regulation of biological process • cellular metabolism • nucleobase, nucleoside, nucleotide and nucleic acid metabolism • regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism • negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism • negative regulation of transcription • negative regulation of transcription, DNA-dependent • negative regulation of transcription from RNA polymerase II promoter • regulation of transcription • regulation of transcription, DNA-dependent • regulation of transcription from RNA polymerase II promoter • transcription • transcription, DNA-dependent • transcription from RNA polymerase II promoter • regulation of cellular metabolism • negative regulation of cellular metabolism • negative regulation of cellular physiological process • negative regulation of cellular process • metabolism • primary metabolism • regulation of metabolism • negative regulation of metabolism • negative regulation of physiological process • negative regulation of biological process • cellular catabolism • cellular macromolecule catabolism • RNA catabolism • mRNA catabolism • mRNA catabolism, deadenylylation-dependent decay • regulation of RNA metabolism • regulation of RNA stability • regulation of mRNA stability • RNA metabolism • mRNA metabolism • catabolism • macromolecule catabolism • macromolecule metabolism • biopolymer metabolism • poly(A) tail shortening • reproductive cellular physiological process • conjugation • conjugation with cellular fusion • response to pheromone during conjugation with cellular fusion • interaction between organisms • reproductive physiological process • reproduction • sexual reproduction • response to stimulus • response to abiotic stimulus • response to chemical stimulus • response to pheromone
Molecular Function• catalytic activity • hydrolase activity • hydrolase activity, acting on ester bonds • nuclease activity • exonuclease activity • 3'-5' exonuclease activity • 3'-5'-exoribonuclease activity • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters • exoribonuclease activity, producing 5'-phosphomonoesters • exoribonuclease activity • ribonuclease activity
Cellular Component• cell • intracellular • intracellular organelle • intracellular membrane-bound organelle • nucleus • organelle • membrane-bound organelle • cytoplasm • nuclear lumen • nucleoplasm • transcription factor complex • CCR4-NOT complex • CCR4-NOT core complex • membrane-enclosed lumen • organelle lumen • protein complex