Gene NameYDL028C (MPS1)
SGD DescriptionDual-specificity kinase required for spindle pole body (SPB) duplication and spindle checkpoint function; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, and checkpoint protein Mad1p
Biological Process• cellular process • cellular physiological process • cell cycle • M phase • M phase of mitotic cell cycle • mitosis • regulation of mitosis • mitotic checkpoint • mitotic spindle checkpoint • mitotic cell cycle • regulation of cell cycle • regulation of progression through cell cycle • cell cycle checkpoint • spindle checkpoint • regulation of cellular physiological process • regulation of cellular process • physiological process • regulation of physiological process • regulation of biological process • cell organization and biogenesis • organelle organization and biogenesis • microtubule organizing center organization and biogenesis • spindle pole body organization and biogenesis • spindle pole body duplication • spindle pole body duplication in nuclear envelope • mitotic spindle organization and biogenesis • mitotic spindle assembly • cytoskeleton organization and biogenesis • microtubule-based process • microtubule cytoskeleton organization and biogenesis • spindle organization and biogenesis • spindle assembly • metabolism • macromolecule metabolism • protein metabolism • protein complex assembly • primary metabolism
Molecular Function• catalytic activity • transferase activity • transferase activity, transferring phosphorus-containing groups • kinase activity • protein kinase activity • protein threonine/tyrosine kinase activity • phosphotransferase activity, alcohol group as acceptor
Cellular Component• cell • intracellular • chromosome • chromosome, pericentric region • condensed chromosome, pericentric region • condensed chromosome kinetochore • condensed nuclear chromosome kinetochore • condensed nuclear chromosome, pericentric region • kinetochore • condensed chromosome • condensed nuclear chromosome • nuclear chromosome • intracellular organelle • intracellular membrane-bound organelle • nucleus • intracellular non-membrane-bound organelle • organelle • membrane-bound organelle • non-membrane-bound organelle • cytoplasm • microtubule organizing center • spindle pole body • cytoskeleton • microtubule cytoskeleton • spindle • spindle pole