Re-run this search with the SEG filter switched off

Re-run this search as BLASTX i.e. nucleotide query

Get selected genes'

Hit NameAncStatusLength (aa)HSP LengthHSP ScoreHSP E-value
Skud_9.792.287ON37137119560.0
YIL094C (LYS12)2.287ON37137119000.0
Smik_9.852.287ON37137118990.0
Suva_9.1052.287ON37137118860.0
NCAS0B062502.287ON37337317230.0
KNAG0A054202.287ON37237117190.0
NDAI0B035502.287ON37237216960.0
TDEL0G021802.287ON36937116570.0
CAGL0G02585g2.287ON37237216410.0
ZYRO0A01914g2.287ON36837116070.0
KAFR0J013602.287ON37337215710.0
KLTH0G10384g2.287ON36737115620.0
KLLA0E08339g2.287ON36937115530.0
Kwal_27.115282.287ON36735315520.0
SAKL0E07656g2.287ON36837115360.0
Kpol_1003.392.287ON37037115250.0
TBLA0B059402.287ON36937215230.0
TPHA0C034102.287ON37136915140.0
Ecym_33262.287ON36635514020.0
ADL214C2.287ON36737113610.0
KLLA0F04103g2.278ON3613504778e-56
ADL223W2.278ON3623834779e-56
NDAI0C014105.473ON3693904761e-55
Kwal_23.50122.278ON3613704724e-55
SAKL0E07876g2.278ON3613824716e-55
TPHA0D015602.278ON3603524708e-55
KLLA0E03125g5.473ON3683954664e-54
Smik_15.3165.473ON3693904579e-53
Ecym_33162.278ON3623504561e-52
NCAS0H022505.473ON4223904591e-52
KLTH0G10186g2.278ON3603504542e-52
Suva_8.1885.473ON3693534525e-52
NCAS0B062902.278ON3593834506e-52
YNL037C (IDH1)2.278ON3603724509e-52
Smik_14.2902.278ON3603724491e-51
KLTH0F15048g5.473ON3683904491e-51
KNAG0B040705.473ON3733604482e-51
Skud_14.2932.278ON3613724463e-51
TBLA0B022405.473ON3733984464e-51
YOR136W (IDH2)5.473ON3693904456e-51
CAGL0I07227g5.473ON3683824431e-50
TDEL0C038402.278ON3613744421e-50
Kpol_543.85.473ON3683604412e-50
Skud_15.3005.473ON3693904403e-50
Ecym_23135.473ON3703534403e-50
AFR137C5.473ON3673664403e-50
SAKL0G03520g5.473ON3693604394e-50
TBLA0B069102.278ON3653904378e-50
Kpol_1039.352.278ON3593854368e-50
Kwal_55.212735.473ON3683534378e-50
NDAI0B035902.278ON3593514298e-49
ZYRO0D02838g2.278ON3613834291e-48
CAGL0G02673g2.278ON3583824272e-48
TPHA0J027705.473ON3763754272e-48
KAFR0B063705.473ON3783574273e-48
TDEL0A033705.473ON3713574246e-48
Kpol_440.125.473ON3683894211e-47
ZYRO0D11220g5.473ON3683524151e-46
KAFR0J014102.278ON3503774105e-46
TPHA0E014805.473ON3773603942e-43
TBLA0C015001.402ON3653693862e-42
KNAG0A052802.278ON3613743844e-42
TDEL0B060001.402ON3623693634e-39
Ecym_12961.402ON3633663601e-38
AAL012C1.402ON3723683601e-38
KLLA0D04906g1.402ON3623713573e-38
Kpol_1048.631.402ON3643693564e-38
Smik_3.661.402ON3643683556e-38
YCL018W (LEU2)1.402ON3643683556e-38
KLTH0H12188g1.402ON3643683503e-37
NDAI0G042301.402ON3633683485e-37
Skud_3.431.402ON3643683487e-37
Suva_14.3022.278ON3003183437e-37
Suva_3.31.402ON3643643434e-36
CAGL0H03795g1.402ON3653663416e-36
KNAG0I012801.402ON4473733431e-35
ZYRO0E04796g1.402ON3623673381e-35
Kwal_0.2251.402ON3643723363e-35
KAFR0I022001.402ON3653643223e-33
NCAS0C048701.402ON3653693162e-32
SAKL0D08690g1.402ON3643693153e-32
TPHA0B037301.402ON3653722987e-30
KAFR0H031601.396ON4211271434e-09
Kwal_23.42104.254ON4222061391e-08
Kpol_1055.784.254ON4272091372e-08
CAGL0H03663g1.396ON4181261345e-08
YDL066W (IDP1)4.254ON4281061345e-08
CAGL0D00770g4.254ON4231151337e-08
TPHA0B022104.254ON4331731321e-07
Skud_4.1894.254ON4291151292e-07
NDAI0D043604.254ON4241151292e-07
KNAG0H016701.396ON4241261292e-07
SAKL0H02860g4.254ON4212061283e-07
TBLA0C012901.396ON4181261283e-07
ZYRO0E05016g1.396ON4111271273e-07
Ecym_13061.396ON4151261265e-07
KAFR0I021301.396ON4081061257e-07
KNAG0I013201.396ON4121061248e-07
KLTH0H12012g1.396ON4132201248e-07
NCAS0G036201.396ON4181061248e-07
KLLA0B03355g4.254ON4292041249e-07
SAKL0D08426g1.396ON4111261231e-06
AER061C4.254ON4251151231e-06
AAL022W1.396ON4151261231e-06
Smik_4.1694.254ON4281061231e-06
KAFR0G032604.254ON4211981222e-06
YNL009W (IDP3)1.396ON4202201222e-06
NCAS0A087201.396ON4131291212e-06
CAGL0B04917g1.396ON4111301212e-06
Suva_4.1844.254ON4291061212e-06
Smik_14.3191.396ON4181261212e-06
KLTH0D14476g4.254ON4201821212e-06
KNAG0D044104.254ON4281281212e-06
TDEL0B061001.396ON4141271202e-06
Kpol_1048.701.396ON4191061202e-06
TDEL0E011604.254ON4231151193e-06
Smik_12.2351.396ON4122181193e-06
NDAI0G008501.396ON4192051193e-06
NCAS0A025104.254ON4261061193e-06
Skud_14.3181.396ON4201261194e-06
Suva_14.3391.396ON4171261185e-06
Skud_12.2391.396ON4121261176e-06
Kwal_0.1911.396ON4111271176e-06
TBLA0A080104.254ON4281061176e-06
YLR174W (IDP2)1.396ON4122181167e-06
Suva_10.2711.396ON4121261159e-06
KLLA0F12342g1.396ON4151061151e-05
ZYRO0B12496g4.254ON4221071151e-05
TPHA0B036601.396ON4221261132e-05
Ecym_32654.254ON4241071104e-05
Suva_14.303singletonON5350932e-04
NDAI0G051601.396ON420126990.001
NCAS0F035003.482ON55455731.8
KNAG0A037508.531ON83065722.4
Ecym_81101.168ON41272694.2
BLASTP 2.2.26 [Sep-21-2011]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= Skud_9.79
         (371 letters)

Database: Seq/AA.fsa 
           114,666 sequences; 53,481,399 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Skud_9.79 Chr9 complement(163173..164288) [1116 bp, 371 aa] {ON}...   758   0.0  
YIL094C Chr9 complement(186517..187632) [1116 bp, 371 aa] {ON}  ...   736   0.0  
Smik_9.85 Chr9 complement(165648..166763) [1116 bp, 371 aa] {ON}...   736   0.0  
Suva_9.105 Chr9 complement(180626..181741) [1116 bp, 371 aa] {ON...   731   0.0  
NCAS0B06250 Chr2 (1179360..1180481) [1122 bp, 373 aa] {ON} Anc_2...   668   0.0  
KNAG0A05420 Chr1 (799521..800639) [1119 bp, 372 aa] {ON}              666   0.0  
NDAI0B03550 Chr2 (891508..892626) [1119 bp, 372 aa] {ON} Anc_2.2...   657   0.0  
TDEL0G02180 Chr7 complement(428789..429898) [1110 bp, 369 aa] {O...   642   0.0  
CAGL0G02585g Chr7 (238931..240049) [1119 bp, 372 aa] {ON} highly...   636   0.0  
ZYRO0A01914g Chr1 complement(158403..159509) [1107 bp, 368 aa] {...   623   0.0  
KAFR0J01360 Chr10 (249197..250318) [1122 bp, 373 aa] {ON} Anc_2....   609   0.0  
KLTH0G10384g Chr7 complement(878375..879478) [1104 bp, 367 aa] {...   606   0.0  
KLLA0E08339g Chr5 (750670..751779) [1110 bp, 369 aa] {ON} highly...   602   0.0  
Kwal_27.11528 s27 (836437..837540) [1104 bp, 367 aa] {ON} YIL094...   602   0.0  
SAKL0E07656g Chr5 (620028..621134) [1107 bp, 368 aa] {ON} highly...   596   0.0  
Kpol_1003.39 s1003 complement(96083..97195) [1113 bp, 370 aa] {O...   592   0.0  
TBLA0B05940 Chr2 complement(1402869..1403978) [1110 bp, 369 aa] ...   591   0.0  
TPHA0C03410 Chr3 complement(748639..749754) [1116 bp, 371 aa] {O...   587   0.0  
Ecym_3326 Chr3 complement(624805..625905) [1101 bp, 366 aa] {ON}...   544   0.0  
ADL214C Chr4 complement(328094..329197) [1104 bp, 367 aa] {ON} S...   528   0.0  
KLLA0F04103g Chr6 (389159..390244) [1086 bp, 361 aa] {ON} unipro...   188   8e-56
ADL223W Chr4 (312893..313981) [1089 bp, 362 aa] {ON} Syntenic ho...   188   9e-56
NDAI0C01410 Chr3 complement(295178..296287) [1110 bp, 369 aa] {O...   187   1e-55
Kwal_23.5012 s23 (964254..965339) [1086 bp, 361 aa] {ON} YNL037C...   186   4e-55
SAKL0E07876g Chr5 complement(635705..636790) [1086 bp, 361 aa] {...   186   6e-55
TPHA0D01560 Chr4 complement(321751..322833) [1083 bp, 360 aa] {O...   185   8e-55
KLLA0E03125g Chr5 (288825..289931) [1107 bp, 368 aa] {ON} highly...   184   4e-54
Smik_15.316 Chr15 (541618..542727) [1110 bp, 369 aa] {ON} YOR136...   180   9e-53
Ecym_3316 Chr3 (608744..609832) [1089 bp, 362 aa] {ON} similar t...   180   1e-52
NCAS0H02250 Chr8 (441692..442960) [1269 bp, 422 aa] {ON} Anc_5.473    181   1e-52
KLTH0G10186g Chr7 (863151..864233) [1083 bp, 360 aa] {ON} highly...   179   2e-52
Suva_8.188 Chr8 (335409..336518) [1110 bp, 369 aa] {ON} YOR136W ...   178   5e-52
NCAS0B06290 Chr2 complement(1186838..1187917) [1080 bp, 359 aa] ...   177   6e-52
YNL037C Chr14 complement(557920..559002) [1083 bp, 360 aa] {ON} ...   177   9e-52
Smik_14.290 Chr14 (528131..529213) [1083 bp, 360 aa] {ON} YNL037...   177   1e-51
KLTH0F15048g Chr6 complement(1232566..1233672) [1107 bp, 368 aa]...   177   1e-51
KNAG0B04070 Chr2 complement(778658..779779) [1122 bp, 373 aa] {O...   177   2e-51
Skud_14.293 Chr14 (538202..539287) [1086 bp, 361 aa] {ON} YNL037...   176   3e-51
TBLA0B02240 Chr2 complement(524111..525232) [1122 bp, 373 aa] {O...   176   4e-51
YOR136W Chr15 (580250..581359) [1110 bp, 369 aa] {ON}  IDH2Subun...   176   6e-51
CAGL0I07227g Chr9 complement(696605..697711) [1107 bp, 368 aa] {...   175   1e-50
TDEL0C03840 Chr3 complement(673007..674092) [1086 bp, 361 aa] {O...   174   1e-50
Kpol_543.8 s543 (21411..22517) [1107 bp, 368 aa] {ON} (21411..22...   174   2e-50
Skud_15.300 Chr15 (534346..535455) [1110 bp, 369 aa] {ON} YOR136...   174   3e-50
Ecym_2313 Chr2 complement(610493..611605) [1113 bp, 370 aa] {ON}...   174   3e-50
AFR137C Chr6 complement(685586..686689) [1104 bp, 367 aa] {ON} S...   174   3e-50
SAKL0G03520g Chr7 (290768..291877) [1110 bp, 369 aa] {ON} highly...   173   4e-50
TBLA0B06910 Chr2 (1634845..1635942) [1098 bp, 365 aa] {ON}            172   8e-50
Kpol_1039.35 s1039 complement(108102..109181) [1080 bp, 359 aa] ...   172   8e-50
Kwal_55.21273 s55 complement(762121..763227) [1107 bp, 368 aa] {...   172   8e-50
NDAI0B03590 Chr2 complement(901108..902187) [1080 bp, 359 aa] {O...   169   8e-49
ZYRO0D02838g Chr4 (223132..224217) [1086 bp, 361 aa] {ON} simila...   169   1e-48
CAGL0G02673g Chr7 complement(246455..247531) [1077 bp, 358 aa] {...   169   2e-48
TPHA0J02770 Chr10 (617727..618857) [1131 bp, 376 aa] {ON} Anc_2....   169   2e-48
KAFR0B06370 Chr2 complement(1317952..1319088) [1137 bp, 378 aa] ...   169   3e-48
TDEL0A03370 Chr1 (599855..600970) [1116 bp, 371 aa] {ON} Anc_5.4...   167   6e-48
Kpol_440.12 s440 (32084..33190) [1107 bp, 368 aa] {ON} (32084..3...   166   1e-47
ZYRO0D11220g Chr4 (946652..947758) [1107 bp, 368 aa] {ON} highly...   164   1e-46
KAFR0J01410 Chr10 complement(256693..257745) [1053 bp, 350 aa] {...   162   5e-46
TPHA0E01480 Chr5 complement(300222..301355) [1134 bp, 377 aa] {O...   156   2e-43
TBLA0C01500 Chr3 complement(347212..348309) [1098 bp, 365 aa] {O...   153   2e-42
KNAG0A05280 Chr1 (780448..781533) [1086 bp, 361 aa] {ON}              152   4e-42
TDEL0B06000 Chr2 (1060828..1061916) [1089 bp, 362 aa] {ON} Anc_1...   144   4e-39
Ecym_1296 Chr1 (602530..603621) [1092 bp, 363 aa] {ON} similar t...   143   1e-38
AAL012C Chr1 complement(320148..321266) [1119 bp, 372 aa] {ON} S...   143   1e-38
KLLA0D04906g Chr4 (420903..421991) [1089 bp, 362 aa] {ON} highly...   142   3e-38
Kpol_1048.63 s1048 (182096..183190) [1095 bp, 364 aa] {ON} (1820...   141   4e-38
Smik_3.66 Chr3 (89718..90812) [1095 bp, 364 aa] {ON} YCL018W (REAL)   141   6e-38
YCL018W Chr3 (91324..92418) [1095 bp, 364 aa] {ON}  LEU2Beta-iso...   141   6e-38
KLTH0H12188g Chr8 (1039347..1040441) [1095 bp, 364 aa] {ON} high...   139   3e-37
NDAI0G04230 Chr7 complement(1015689..1016780) [1092 bp, 363 aa] ...   138   5e-37
Skud_3.43 Chr3 (70293..71387) [1095 bp, 364 aa] {ON} YCL018W (REAL)   138   7e-37
Suva_14.302 Chr14 (546468..547370) [903 bp, 300 aa] {ON} YNL037C...   136   7e-37
Suva_3.3 Chr3 (1464..2558) [1095 bp, 364 aa] {ON} YCL018W (REAL)      136   4e-36
CAGL0H03795g Chr8 (356535..357632) [1098 bp, 365 aa] {ON}             135   6e-36
KNAG0I01280 Chr9 complement(245603..246946) [1344 bp, 447 aa] {O...   136   1e-35
ZYRO0E04796g Chr5 (362881..363969) [1089 bp, 362 aa] {ON} unipro...   134   1e-35
Kwal_0.225 s0 (111017..112111) [1095 bp, 364 aa] {ON} YCL018W (L...   134   3e-35
KAFR0I02200 Chr9 (449737..450834) [1098 bp, 365 aa] {ON} Anc_1.4...   128   3e-33
NCAS0C04870 Chr3 complement(993177..994274) [1098 bp, 365 aa] {O...   126   2e-32
SAKL0D08690g Chr4 complement(723302..724396) [1095 bp, 364 aa] {...   125   3e-32
TPHA0B03730 Chr2 complement(878199..879296) [1098 bp, 365 aa] {O...   119   7e-30
KAFR0H03160 Chr8 complement(602807..604072) [1266 bp, 421 aa] {O...    60   4e-09
Kwal_23.4210 s23 (619516..620784) [1269 bp, 422 aa] {ON} YDL066W...    58   1e-08
Kpol_1055.78 s1055 (207889..209172) [1284 bp, 427 aa] {ON} (2078...    57   2e-08
CAGL0H03663g Chr8 (337533..338789) [1257 bp, 418 aa] {ON} highly...    56   5e-08
YDL066W Chr4 (334835..336121) [1287 bp, 428 aa] {ON}  IDP1Mitoch...    56   5e-08
CAGL0D00770g Chr4 (95715..96986) [1272 bp, 423 aa] {ON} highly s...    56   7e-08
TPHA0B02210 Chr2 (509945..511246) [1302 bp, 433 aa] {ON} Anc_4.2...    55   1e-07
Skud_4.189 Chr4 (330300..331589) [1290 bp, 429 aa] {ON} YDL066W ...    54   2e-07
NDAI0D04360 Chr4 (1024297..1025571) [1275 bp, 424 aa] {ON} Anc_4...    54   2e-07
KNAG0H01670 Chr8 (298481..299755) [1275 bp, 424 aa] {ON} Anc_1.3...    54   2e-07
SAKL0H02860g Chr8 (280944..282209) [1266 bp, 421 aa] {ON} highly...    54   3e-07
TBLA0C01290 Chr3 complement(283624..284880) [1257 bp, 418 aa] {O...    54   3e-07
ZYRO0E05016g Chr5 complement(379654..380889) [1236 bp, 411 aa] {...    54   3e-07
Ecym_1306 Chr1 complement(619565..620812) [1248 bp, 415 aa] {ON}...    53   5e-07
KAFR0I02130 Chr9 (438428..439654) [1227 bp, 408 aa] {ON} Anc_1.3...    53   7e-07
KNAG0I01320 Chr9 complement(255478..256716) [1239 bp, 412 aa] {O...    52   8e-07
KLTH0H12012g Chr8 (1026586..1027827) [1242 bp, 413 aa] {ON} high...    52   8e-07
NCAS0G03620 Chr7 complement(675224..676480) [1257 bp, 418 aa] {O...    52   8e-07
KLLA0B03355g Chr2 (303444..304733) [1290 bp, 429 aa] {ON} highly...    52   9e-07
SAKL0D08426g Chr4 (705189..706424) [1236 bp, 411 aa] {ON} highly...    52   1e-06
AER061C Chr5 complement(749709..750986) [1278 bp, 425 aa] {ON} S...    52   1e-06
AAL022W Chr1 (302946..304193) [1248 bp, 415 aa] {ON} Syntenic ho...    52   1e-06
Smik_4.169 Chr4 (311244..312530) [1287 bp, 428 aa] {ON} YDL066W ...    52   1e-06
KAFR0G03260 Chr7 complement(675642..676907) [1266 bp, 421 aa] {O...    52   2e-06
YNL009W Chr14 (614821..616083) [1263 bp, 420 aa] {ON}  IDP3Perox...    52   2e-06
NCAS0A08720 Chr1 complement(1722511..1723752) [1242 bp, 413 aa] ...    51   2e-06
CAGL0B04917g Chr2 complement(477939..479174) [1236 bp, 411 aa] {...    51   2e-06
Suva_4.184 Chr4 (324382..325671) [1290 bp, 429 aa] {ON} YDL066W ...    51   2e-06
Smik_14.319 Chr14 (573167..574423) [1257 bp, 418 aa] {ON} YLR174...    51   2e-06
KLTH0D14476g Chr4 complement(1184813..1186075) [1263 bp, 420 aa]...    51   2e-06
KNAG0D04410 Chr4 complement(799414..800700) [1287 bp, 428 aa] {O...    51   2e-06
TDEL0B06100 Chr2 complement(1076365..1077609) [1245 bp, 414 aa] ...    51   2e-06
Kpol_1048.70 s1048 complement(198298..199557) [1260 bp, 419 aa] ...    51   2e-06
TDEL0E01160 Chr5 (234217..235488) [1272 bp, 423 aa] {ON} Anc_4.2...    50   3e-06
Smik_12.235 Chr12 (451719..452957) [1239 bp, 412 aa] {ON} YLR174...    50   3e-06
NDAI0G00850 Chr7 (179074..180333) [1260 bp, 419 aa] {ON} Anc_1.396     50   3e-06
NCAS0A02510 Chr1 complement(476363..477643) [1281 bp, 426 aa] {O...    50   3e-06
Skud_14.318 Chr14 (581597..582859) [1263 bp, 420 aa] {ON} YNL009...    50   4e-06
Suva_14.339 Chr14 (594794..596047) [1254 bp, 417 aa] {ON} YNL009...    50   5e-06
Skud_12.239 Chr12 (451342..452580) [1239 bp, 412 aa] {ON} YLR174...    50   6e-06
Kwal_0.191 s0 (98033..99268) [1236 bp, 411 aa] {ON} YLR174W (IDP...    50   6e-06
TBLA0A08010 Chr1 (1981576..1982862) [1287 bp, 428 aa] {ON} Anc_4...    50   6e-06
YLR174W Chr12 (504591..505829) [1239 bp, 412 aa] {ON}  IDP2Cytos...    49   7e-06
Suva_10.271 Chr10 (476726..477964) [1239 bp, 412 aa] {ON} YLR174...    49   9e-06
KLLA0F12342g Chr6 (1137608..1138855) [1248 bp, 415 aa] {ON} high...    49   1e-05
ZYRO0B12496g Chr2 complement(1007086..1008354) [1269 bp, 422 aa]...    49   1e-05
TPHA0B03660 Chr2 (863280..864548) [1269 bp, 422 aa] {ON} Anc_1.3...    48   2e-05
Ecym_3265 Chr3 (504267..505541) [1275 bp, 424 aa] {ON} similar t...    47   4e-05
Suva_14.303 Chr14 (547367..547525) [159 bp, 53 aa] {ON} YNL037C ...    40   2e-04
NDAI0G05160 Chr7 complement(1250883..1252145) [1263 bp, 420 aa] ...    43   0.001
NCAS0F03500 Chr6 complement(700666..702330) [1665 bp, 554 aa] {O...    33   1.8  
KNAG0A03750 Chr1 (487451..489943) [2493 bp, 830 aa] {ON} Anc_8.5...    32   2.4  
Ecym_8110 Chr8 (234106..235344) [1239 bp, 412 aa] {ON} similar t...    31   4.2  

>Skud_9.79 Chr9 complement(163173..164288) [1116 bp, 371 aa] {ON}
           YIL094C (REAL)
          Length = 371

 Score =  758 bits (1956), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 371/371 (100%), Positives = 371/371 (100%)

Query: 1   MFRSVATRVSACRGLATNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFI 60
           MFRSVATRVSACRGLATNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFI
Sbjct: 1   MFRSVATRVSACRGLATNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFI 60

Query: 61  DLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLF 120
           DLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLF
Sbjct: 61  DLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLF 120

Query: 121 ANVRPVKSVEGSRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRR 180
           ANVRPVKSVEGSRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRR
Sbjct: 121 ANVRPVKSVEGSRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRR 180

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQ 240
           IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQ
Sbjct: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQ 240

Query: 241 IVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCHG 300
           IVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCHG
Sbjct: 241 IVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCHG 300

Query: 301 SAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKAST 360
           SAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKAST
Sbjct: 301 SAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKAST 360

Query: 361 QQVVDDVLSRL 371
           QQVVDDVLSRL
Sbjct: 361 QQVVDDVLSRL 371

>YIL094C Chr9 complement(186517..187632) [1116 bp, 371 aa] {ON}
           LYS12Homo-isocitrate dehydrogenase, an NAD-linked
           mitochondrial enzyme required for the fourth step in the
           biosynthesis of lysine, in which homo-isocitrate is
           oxidatively decarboxylated to alpha-ketoadipate
          Length = 371

 Score =  736 bits (1900), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 359/371 (96%), Positives = 366/371 (98%)

Query: 1   MFRSVATRVSACRGLATNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFI 60
           MFRSVATR+SACRGLA+NAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFI
Sbjct: 1   MFRSVATRLSACRGLASNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFI 60

Query: 61  DLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLF 120
           DLYAGFQTFQETGKALPDETV VLK+QCQGALFGAVQSPTTKVEGYSSPIVALRREMGLF
Sbjct: 61  DLYAGFQTFQETGKALPDETVKVLKEQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLF 120

Query: 121 ANVRPVKSVEGSRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRR 180
           ANVRPVKSVEG + KPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRR
Sbjct: 121 ANVRPVKSVEGEKGKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRR 180

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQ 240
           IATIALDIALKRLQTRG+ATLTVTHKSNVLSQ+DGLFREICKEVYESNKDKYGQIKYNEQ
Sbjct: 181 IATIALDIALKRLQTRGQATLTVTHKSNVLSQSDGLFREICKEVYESNKDKYGQIKYNEQ 240

Query: 241 IVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCHG 300
           IVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCHG
Sbjct: 241 IVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCHG 300

Query: 301 SAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKAST 360
           SAPDIAGKGIANPIATIRSTALMLEFLGHN AAQDIYKAVDANLREG+I TPDLGGKAST
Sbjct: 301 SAPDIAGKGIANPIATIRSTALMLEFLGHNEAAQDIYKAVDANLREGSIKTPDLGGKAST 360

Query: 361 QQVVDDVLSRL 371
           QQVVDDVLSRL
Sbjct: 361 QQVVDDVLSRL 371

>Smik_9.85 Chr9 complement(165648..166763) [1116 bp, 371 aa] {ON}
           YIL094C (REAL)
          Length = 371

 Score =  736 bits (1899), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 358/371 (96%), Positives = 365/371 (98%)

Query: 1   MFRSVATRVSACRGLATNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFI 60
           M RSVATR+S CRGLATNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFI
Sbjct: 1   MLRSVATRLSTCRGLATNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFI 60

Query: 61  DLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLF 120
           DLYAGFQTFQETGKALPDETV VLK+QCQGALFGAVQSPTTKVEGYSSPIVALRREMGLF
Sbjct: 61  DLYAGFQTFQETGKALPDETVKVLKEQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLF 120

Query: 121 ANVRPVKSVEGSRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRR 180
           ANVRPVKSVEG ++KPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRR
Sbjct: 121 ANVRPVKSVEGGKDKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRR 180

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQ 240
           IATIA+DIALKRLQTRGEATLTVTHKSNVLSQ+DGLFREICKEVYESNKDKYGQIKYNEQ
Sbjct: 181 IATIAMDIALKRLQTRGEATLTVTHKSNVLSQSDGLFREICKEVYESNKDKYGQIKYNEQ 240

Query: 241 IVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCHG 300
           IVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCHG
Sbjct: 241 IVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCHG 300

Query: 301 SAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKAST 360
           SAPDIAGKGIANPIATIRSTALMLEFLGHN AAQDIYKAVDANLREGAI TPDLGGKAST
Sbjct: 301 SAPDIAGKGIANPIATIRSTALMLEFLGHNNAAQDIYKAVDANLREGAIKTPDLGGKAST 360

Query: 361 QQVVDDVLSRL 371
           QQVV+DVLSRL
Sbjct: 361 QQVVEDVLSRL 371

>Suva_9.105 Chr9 complement(180626..181741) [1116 bp, 371 aa] {ON}
           YIL094C (REAL)
          Length = 371

 Score =  731 bits (1886), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 353/371 (95%), Positives = 366/371 (98%)

Query: 1   MFRSVATRVSACRGLATNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFI 60
           MFRSVATR+SACRGLA+NAARKSLTIGLIPGDGIGKEVIPAGKQ+LENLNSKHGLSFNFI
Sbjct: 1   MFRSVATRISACRGLASNAARKSLTIGLIPGDGIGKEVIPAGKQILENLNSKHGLSFNFI 60

Query: 61  DLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLF 120
           DLYAGFQTFQETGKALPDET+ VLK QCQGALFGAVQSPTTKVEGYSSPIVALRREMGL+
Sbjct: 61  DLYAGFQTFQETGKALPDETIKVLKDQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLY 120

Query: 121 ANVRPVKSVEGSRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRR 180
           ANVRPVKSVEG+++KPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADA KRISE+ATRR
Sbjct: 121 ANVRPVKSVEGTKDKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADAIKRISEVATRR 180

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQ 240
           IA IALDIAL+RLQTRGEATLTVTHKSNVLSQ+DGLFREICK+VYESNKDKYGQIKYNEQ
Sbjct: 181 IAKIALDIALQRLQTRGEATLTVTHKSNVLSQSDGLFREICKDVYESNKDKYGQIKYNEQ 240

Query: 241 IVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCHG 300
           IVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGP+IVIGEPCHG
Sbjct: 241 IVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPDIVIGEPCHG 300

Query: 301 SAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKAST 360
           SAPDIAGKGIANPIATIRSTALMLEFLGHN AAQDIYKAVDANLREGAITTPDLGGKAST
Sbjct: 301 SAPDIAGKGIANPIATIRSTALMLEFLGHNDAAQDIYKAVDANLREGAITTPDLGGKAST 360

Query: 361 QQVVDDVLSRL 371
           QQVVDDVLSRL
Sbjct: 361 QQVVDDVLSRL 371

>NCAS0B06250 Chr2 (1179360..1180481) [1122 bp, 373 aa] {ON}
           Anc_2.287
          Length = 373

 Score =  668 bits (1723), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 322/373 (86%), Positives = 348/373 (93%), Gaps = 2/373 (0%)

Query: 1   MFRSVATR--VSACRGLATNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFN 58
           M R+ A+R   S CR  ATNA RK+LTIGLIPGDGIGKEVIPAGKQVLENLNSKHGL F+
Sbjct: 1   MLRTAASRFATSTCRTYATNALRKNLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLKFD 60

Query: 59  FIDLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMG 118
           FIDL AGFQTF +TGKALPDETV VLK QCQGALFGAVQSPTTKVEGYSSPIVALR+EMG
Sbjct: 61  FIDLQAGFQTFLDTGKALPDETVQVLKSQCQGALFGAVQSPTTKVEGYSSPIVALRKEMG 120

Query: 119 LFANVRPVKSVEGSRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIAT 178
           LFANVRPVKSV G++++P+DMVIVRENTEDLYIKIEKTYIDKATGTRVA+ATKRISEIAT
Sbjct: 121 LFANVRPVKSVSGTKDRPVDMVIVRENTEDLYIKIEKTYIDKATGTRVAEATKRISEIAT 180

Query: 179 RRIATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYN 238
           RRIATIALDIAL+RL+  G+ATLTVTHKSNVLSQ+DGLFREICK+VYESNKDKYG I YN
Sbjct: 181 RRIATIALDIALQRLKVNGKATLTVTHKSNVLSQSDGLFREICKDVYESNKDKYGSITYN 240

Query: 239 EQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPC 298
           EQIVDSMVYR+FREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPC
Sbjct: 241 EQIVDSMVYRMFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPC 300

Query: 299 HGSAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKA 358
           HGSAPDIAGKGIANPIATIRSTALMLEFLGHN AAQDI++AV+AN+RE  I TPDLGG +
Sbjct: 301 HGSAPDIAGKGIANPIATIRSTALMLEFLGHNDAAQDIHRAVEANMRENKIKTPDLGGNS 360

Query: 359 STQQVVDDVLSRL 371
           +TQQV +DVL+RL
Sbjct: 361 TTQQVTEDVLARL 373

>KNAG0A05420 Chr1 (799521..800639) [1119 bp, 372 aa] {ON} 
          Length = 372

 Score =  666 bits (1719), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 316/371 (85%), Positives = 350/371 (94%)

Query: 1   MFRSVATRVSACRGLATNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFI 60
           M RS A +++ CRGLATNAARKSLTIGLIPGDGIGKEVIPAGKQVL++LN KHGL+F+FI
Sbjct: 2   MLRSAANKLAGCRGLATNAARKSLTIGLIPGDGIGKEVIPAGKQVLQSLNPKHGLNFDFI 61

Query: 61  DLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLF 120
           DL AGFQTFQ+TGKALPDETV +LK++CQGALFGAVQSPTTKVEGYSSPIVALR+ MGL+
Sbjct: 62  DLQAGFQTFQDTGKALPDETVQILKEKCQGALFGAVQSPTTKVEGYSSPIVALRKAMGLY 121

Query: 121 ANVRPVKSVEGSRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRR 180
           AN+RPVKSVEGS  +P+DM+IVRENTEDLYIKIEKTYIDKATGTRVA+ATKRISEIAT+R
Sbjct: 122 ANIRPVKSVEGSNERPVDMIIVRENTEDLYIKIEKTYIDKATGTRVAEATKRISEIATQR 181

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQ 240
           IATIALDIAL+RLQ  G+ATLTVTHKSNVLSQ+DGLFRE+C+E+YE+NKDKY  I YNEQ
Sbjct: 182 IATIALDIALQRLQNNGKATLTVTHKSNVLSQSDGLFREVCREMYEANKDKYAGITYNEQ 241

Query: 241 IVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCHG 300
           IVDSMVYR+FREP+CFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCHG
Sbjct: 242 IVDSMVYRMFREPECFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCHG 301

Query: 301 SAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKAST 360
           SAPDIAGKGIANPIATIRSTALMLEFLGHN AAQDI+KAVDANLR+G + T DLGG A+T
Sbjct: 302 SAPDIAGKGIANPIATIRSTALMLEFLGHNEAAQDIHKAVDANLRDGLVKTADLGGNATT 361

Query: 361 QQVVDDVLSRL 371
           Q VVDD+L+RL
Sbjct: 362 QNVVDDILARL 372

>NDAI0B03550 Chr2 (891508..892626) [1119 bp, 372 aa] {ON} Anc_2.287
           YIL094C
          Length = 372

 Score =  657 bits (1696), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 313/372 (84%), Positives = 351/372 (94%), Gaps = 1/372 (0%)

Query: 1   MFRSVATRVSACRGLATNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFI 60
           M R+ A+R++ CRG ATNA RK+LTIGLIPGDGIGKEVIPAGKQVL+NLNSKHGL+F+FI
Sbjct: 1   MLRTTASRLATCRGYATNAIRKNLTIGLIPGDGIGKEVIPAGKQVLQNLNSKHGLNFDFI 60

Query: 61  DLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLF 120
           DL AGFQTF +TGKALPDET+ VLK QCQGALFGAVQSPTTKVEGYSSPIVALR+EMGL+
Sbjct: 61  DLQAGFQTFLDTGKALPDETIQVLKNQCQGALFGAVQSPTTKVEGYSSPIVALRKEMGLY 120

Query: 121 ANVRPVKSVEGSRNKPIDMVIVRENTED-LYIKIEKTYIDKATGTRVADATKRISEIATR 179
           ANVRPVKSVEG+ +KP+DMVIVRENT   + IK+E+TYID+ATGTRVA+ATKRISEIATR
Sbjct: 121 ANVRPVKSVEGTTDKPVDMVIVRENTRRFINIKLERTYIDRATGTRVAEATKRISEIATR 180

Query: 180 RIATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNE 239
           RIATIALDIAL+RL+T G+ATLTVTHKSNVLSQ+DGLFREICK+VYESNKDKYGQI YNE
Sbjct: 181 RIATIALDIALQRLKTNGKATLTVTHKSNVLSQSDGLFREICKDVYESNKDKYGQINYNE 240

Query: 240 QIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCH 299
           QIVDSMVYR+FREPQCFDV+VAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCH
Sbjct: 241 QIVDSMVYRMFREPQCFDVVVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCH 300

Query: 300 GSAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKAS 359
           GSAPDIAGKGI+NPIATIRSTALMLEFLGHN AAQDI++AV+ANL+E  + TPDLGGK++
Sbjct: 301 GSAPDIAGKGISNPIATIRSTALMLEFLGHNEAAQDIHRAVEANLKENKVKTPDLGGKST 360

Query: 360 TQQVVDDVLSRL 371
           TQ+V +DVL+RL
Sbjct: 361 TQEVTEDVLARL 372

>TDEL0G02180 Chr7 complement(428789..429898) [1110 bp, 369 aa] {ON}
           Anc_2.287 YIL094C
          Length = 369

 Score =  642 bits (1657), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 306/371 (82%), Positives = 344/371 (92%), Gaps = 2/371 (0%)

Query: 1   MFRSVATRVSACRGLATNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFI 60
           M RS   R++  R  A+  A KS+ IGLIPGDGIGKEVIPAGKQVLENL+ KHGL+F+FI
Sbjct: 1   MLRSAIGRLATRRAYAS--APKSMVIGLIPGDGIGKEVIPAGKQVLENLSGKHGLNFDFI 58

Query: 61  DLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLF 120
           DL AG+ TFQETGKALP++TV VLK QCQGALFGAVQSPTTKVEGYSSPIVALR+E+GL+
Sbjct: 59  DLQAGWGTFQETGKALPEQTVQVLKNQCQGALFGAVQSPTTKVEGYSSPIVALRKELGLY 118

Query: 121 ANVRPVKSVEGSRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRR 180
           ANVRPVKSVEG++++P+DMVIVRENTEDLYIK+EKTY+DKATGTRVA+ATKRISE+ATRR
Sbjct: 119 ANVRPVKSVEGTKDRPVDMVIVRENTEDLYIKLEKTYVDKATGTRVAEATKRISEVATRR 178

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQ 240
           IATIALDIAL+RL+T G ATLTVTHKSNVLSQ+DGLFREICK+VYESNKDKYGQ+ YNEQ
Sbjct: 179 IATIALDIALQRLKTNGHATLTVTHKSNVLSQSDGLFREICKDVYESNKDKYGQVAYNEQ 238

Query: 241 IVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCHG 300
           IVDSMVYR+FREP+CFDV+VAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCHG
Sbjct: 239 IVDSMVYRMFREPECFDVVVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCHG 298

Query: 301 SAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKAST 360
           SAPDIAGKGI+NPIATIRST LMLEFLGHN  AQDIY+AVDANLRE  + TPDLGG ++T
Sbjct: 299 SAPDIAGKGISNPIATIRSTGLMLEFLGHNKPAQDIYRAVDANLREDKVKTPDLGGNSTT 358

Query: 361 QQVVDDVLSRL 371
           QQVV+D+LS+L
Sbjct: 359 QQVVEDILSKL 369

>CAGL0G02585g Chr7 (238931..240049) [1119 bp, 372 aa] {ON} highly
           similar to uniprot|P40495 Saccharomyces cerevisiae
           YIL094c LYS12 homo-isocitrate dehydrogenase
          Length = 372

 Score =  636 bits (1641), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 305/372 (81%), Positives = 343/372 (92%), Gaps = 1/372 (0%)

Query: 1   MFRSVATRVSACRGLA-TNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNF 59
           M R  ATR++A RG + T  A+K+LTIGLIPGDGIGKEVIPAGKQ+LE +  K  L F F
Sbjct: 1   MLRGSATRLTAMRGFSSTRLAQKALTIGLIPGDGIGKEVIPAGKQILEKVGPKFDLDFKF 60

Query: 60  IDLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGL 119
           IDL+AG++TFQ TGKALPDETV VL++ CQGALFGAVQSPTTKVEGYSSPIVALR+ MGL
Sbjct: 61  IDLHAGWETFQNTGKALPDETVEVLRRDCQGALFGAVQSPTTKVEGYSSPIVALRKAMGL 120

Query: 120 FANVRPVKSVEGSRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATR 179
           FANVRPVK+VEG+ ++P+DMVIVRENTEDLYIKIEKTY D ATGTRVA+ATKRISE+ATR
Sbjct: 121 FANVRPVKAVEGTNDRPVDMVIVRENTEDLYIKIEKTYTDPATGTRVAEATKRISEVATR 180

Query: 180 RIATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNE 239
           RIATIALDIAL+RLQ+RG ATLTVTHKSNVLSQ+DGLFREICK+VYESNKDKYG+I+YNE
Sbjct: 181 RIATIALDIALQRLQSRGHATLTVTHKSNVLSQSDGLFREICKDVYESNKDKYGKIQYNE 240

Query: 240 QIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCH 299
           QIVDSMVYR+FREP+CFDV+VAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCH
Sbjct: 241 QIVDSMVYRMFREPECFDVVVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCH 300

Query: 300 GSAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKAS 359
           GSAPDIAG+GIANPIATIRSTALMLEFLG+  AAQ IYKAVD+N+RE  I TPDLGGK++
Sbjct: 301 GSAPDIAGRGIANPIATIRSTALMLEFLGYPEAAQPIYKAVDSNIRENQIKTPDLGGKST 360

Query: 360 TQQVVDDVLSRL 371
           TQQVVDD+LS++
Sbjct: 361 TQQVVDDILSKI 372

>ZYRO0A01914g Chr1 complement(158403..159509) [1107 bp, 368 aa] {ON}
           highly similar to uniprot|P40495 Saccharomyces
           cerevisiae YIL094C LYS12 Homo-isocitrate dehydrogenase
           an NAD-linked mitochondrial enzyme required for the
           fourth step in the biosynthesis of lysine in which homo-
           isocitrate is oxidatively decarboxylated to alpha-
           ketoadipate
          Length = 368

 Score =  623 bits (1607), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 298/371 (80%), Positives = 338/371 (91%), Gaps = 3/371 (0%)

Query: 1   MFRSVATRVSACRGLATNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFI 60
           MFRS   +V+A R  +   A KS+ IGLIPGDGIGKEVIPAGKQVLE L SKHGL F+FI
Sbjct: 1   MFRSSVAKVAARRAYS---APKSMKIGLIPGDGIGKEVIPAGKQVLEALGSKHGLQFDFI 57

Query: 61  DLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLF 120
           DL AG++ FQ+ GKALPD+TV VLK+QCQGALFGAVQSPTTKV GYSSPIVALR+E+GL+
Sbjct: 58  DLKAGWEAFQQQGKALPDDTVKVLKEQCQGALFGAVQSPTTKVAGYSSPIVALRKELGLY 117

Query: 121 ANVRPVKSVEGSRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRR 180
           ANVRPVKSVE   ++ +DM+IVRENTEDLYIK EKTY+D+ATGTRVA+A KRISE+ATR+
Sbjct: 118 ANVRPVKSVEKGNDRNVDMIIVRENTEDLYIKTEKTYVDEATGTRVAEAIKRISEVATRK 177

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQ 240
           IATIALDI+L+RL++RG ATLTVTHKSNVLSQ+DGLFREICK+VYE NKDKYG++KYNEQ
Sbjct: 178 IATIALDISLQRLKSRGHATLTVTHKSNVLSQSDGLFREICKDVYEKNKDKYGEVKYNEQ 237

Query: 241 IVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCHG 300
           IVDSMVYR+FREP+CFDV+VAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCHG
Sbjct: 238 IVDSMVYRMFREPECFDVVVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCHG 297

Query: 301 SAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKAST 360
           SAPDIAGKGI+NPIATIRSTALMLEFLGH   AQDIYKAVDANL +G + TPDLGGKA+T
Sbjct: 298 SAPDIAGKGISNPIATIRSTALMLEFLGHPEPAQDIYKAVDANLIKGDVNTPDLGGKATT 357

Query: 361 QQVVDDVLSRL 371
           QQVVDD+LS++
Sbjct: 358 QQVVDDILSKI 368

>KAFR0J01360 Chr10 (249197..250318) [1122 bp, 373 aa] {ON} Anc_2.287
           YIL094C
          Length = 373

 Score =  609 bits (1571), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 292/372 (78%), Positives = 335/372 (90%), Gaps = 2/372 (0%)

Query: 1   MFRSVATRVSACRGLATNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFI 60
           M RSV T+ +  R L+T    KSLTIGLIPGDGIGKEVIPAGKQVL+NL+S+HGL+FNFI
Sbjct: 1   MLRSVVTKSATIRHLSTKGINKSLTIGLIPGDGIGKEVIPAGKQVLQNLSSRHGLNFNFI 60

Query: 61  DLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLF 120
           DL AGFQTF +TGKALPDETV VLK+QCQG LFGAVQSPTT+V+ YSSPIVALR+E+ L+
Sbjct: 61  DLEAGFQTFLDTGKALPDETVKVLKEQCQGVLFGAVQSPTTRVDNYSSPIVALRKELQLY 120

Query: 121 ANVRPVKSVEGSRN-KPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATR 179
           AN+RPVKSV G+ + KP+DMVIVRENTEDLYIKIEK+Y D+  G RVA+ATKRI+E+ATR
Sbjct: 121 ANIRPVKSVAGAHSGKPVDMVIVRENTEDLYIKIEKSYKDQ-NGMRVAEATKRITEVATR 179

Query: 180 RIATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNE 239
           +IA IALD+AL+RL+T G+ATLTVTHKSNVLSQ+DGLFREICK+VY++NKDKY  I YNE
Sbjct: 180 KIAKIALDVALQRLKTNGKATLTVTHKSNVLSQSDGLFREICKDVYQANKDKYAGINYNE 239

Query: 240 QIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCH 299
           QI+DSMVYR+FREP+ FDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGP+IV+GEPCH
Sbjct: 240 QIIDSMVYRMFREPEYFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPDIVMGEPCH 299

Query: 300 GSAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKAS 359
           GSAPDIAGKGIANPIATIRSTALMLEFLGH  AAQDI+KAV++N+RE  I TPDLGG +S
Sbjct: 300 GSAPDIAGKGIANPIATIRSTALMLEFLGHKEAAQDIHKAVESNMRENKIKTPDLGGNSS 359

Query: 360 TQQVVDDVLSRL 371
           TQ VVDDVL +L
Sbjct: 360 TQNVVDDVLEKL 371

>KLTH0G10384g Chr7 complement(878375..879478) [1104 bp, 367 aa] {ON}
           highly similar to uniprot|P40495 Saccharomyces
           cerevisiae YIL094C LYS12 Homo-isocitrate dehydrogenase
           an NAD-linked mitochondrial enzyme required for the
           fourth step in the biosynthesis of lysine in which homo-
           isocitrate is oxidatively decarboxylated to alpha-
           ketoadipate
          Length = 367

 Score =  606 bits (1562), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 292/371 (78%), Positives = 337/371 (90%), Gaps = 4/371 (1%)

Query: 1   MFRSVATRVSACRGLATNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFI 60
           M R+  T++ A R  A+  A KSLTIGLIPGDGIGKEVIPAG+QVLENL+SKHGL F+FI
Sbjct: 1   MLRASFTQL-ARRSYAS--ASKSLTIGLIPGDGIGKEVIPAGRQVLENLSSKHGLKFDFI 57

Query: 61  DLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLF 120
           DL AG+QTFQETGKALPDET+++L+ QCQGALFGAVQSPT KVEGYSSPIVALR+++GL+
Sbjct: 58  DLQAGWQTFQETGKALPDETIDILRNQCQGALFGAVQSPTNKVEGYSSPIVALRKKLGLY 117

Query: 121 ANVRPVKSVEGSRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRR 180
           ANVRPVKSV   + +P+DM+IVRENTEDLYIK EKTYID+ TGTRVA+A KRISE AT+ 
Sbjct: 118 ANVRPVKSVL-PQERPVDMIIVRENTEDLYIKTEKTYIDEKTGTRVAEAIKRISETATKN 176

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQ 240
           IA IAL+IAL+R +  GEATLTVTHKSNVLSQ+DGLFRE+C++VYESNKDK+G IKYNEQ
Sbjct: 177 IANIALEIALQRQKVNGEATLTVTHKSNVLSQSDGLFREVCRQVYESNKDKFGSIKYNEQ 236

Query: 241 IVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCHG 300
           IVDSMVYR+FREP+CFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVG + V+GEPCHG
Sbjct: 237 IVDSMVYRMFREPECFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGFDFVVGEPCHG 296

Query: 301 SAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKAST 360
           SAPDIAGKGI+NP+ATIRSTALMLEF+GH  AAQDI+KAVDANLR+ +I TPDLGGK++T
Sbjct: 297 SAPDIAGKGISNPVATIRSTALMLEFMGHPEAAQDIHKAVDANLRDNSIKTPDLGGKSTT 356

Query: 361 QQVVDDVLSRL 371
           QQVV+DVLSR+
Sbjct: 357 QQVVEDVLSRM 367

>KLLA0E08339g Chr5 (750670..751779) [1110 bp, 369 aa] {ON} highly
           similar to uniprot|P40495 Saccharomyces cerevisiae
           YIL094C LYS12 Homo-isocitrate dehydrogenase an
           NAD-linked mitochondrial enzyme required for the fourth
           step in the biosynthesis of lysine in which homo-
           isocitrate is oxidatively decarboxylated to alpha-
           ketoadipate
          Length = 369

 Score =  602 bits (1553), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 288/371 (77%), Positives = 338/371 (91%), Gaps = 3/371 (0%)

Query: 1   MFRSVATRVSACRGLATNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFI 60
           M R+   ++S  R  A+NA  K+LTIGLIPGDGIGKEVIPAGK++LE+LN K+GLSF FI
Sbjct: 1   MMRTRFIQLSR-RAYASNA--KNLTIGLIPGDGIGKEVIPAGKKILESLNPKYGLSFKFI 57

Query: 61  DLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLF 120
           DL AG++TFQ TGKALPDET+++LK QC+GALFGAVQSPTTKVEGYSSPIVALR+ +GLF
Sbjct: 58  DLQAGWETFQNTGKALPDETIDILKNQCEGALFGAVQSPTTKVEGYSSPIVALRKNLGLF 117

Query: 121 ANVRPVKSVEGSRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRR 180
           ANVRPVKSV+G++++ +D+VIVRENTEDLYIK+EK+YID+ATGTRVADATKRI+EIAT+ 
Sbjct: 118 ANVRPVKSVDGTKDRKVDLVIVRENTEDLYIKLEKSYIDEATGTRVADATKRITEIATKN 177

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQ 240
           IATIAL IA +RL+  G ATLTVTHKSNVLSQ+DGLFRE+C+E YE+NKDKYG ++YNEQ
Sbjct: 178 IATIALQIAQQRLEQNGHATLTVTHKSNVLSQSDGLFREVCRETYEANKDKYGGVQYNEQ 237

Query: 241 IVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCHG 300
           IVDSMVYR+FREP+CFDV+VAPNLYGDILSDGAAALVGSLGVVPSANVGP IVIGEPCHG
Sbjct: 238 IVDSMVYRMFREPECFDVVVAPNLYGDILSDGAAALVGSLGVVPSANVGPNIVIGEPCHG 297

Query: 301 SAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKAST 360
           SAPDIAGKGI+NPIATIRSTALMLEFLG+   A+DI+KAVDAN+REG   TPDLGG ++T
Sbjct: 298 SAPDIAGKGISNPIATIRSTALMLEFLGYPEPAKDIHKAVDANIREGKYLTPDLGGNSTT 357

Query: 361 QQVVDDVLSRL 371
           QQV++DVLS+L
Sbjct: 358 QQVLEDVLSKL 368

>Kwal_27.11528 s27 (836437..837540) [1104 bp, 367 aa] {ON} YIL094C
           (LYS12) - Homo-isocitrate dehydrogenase [contig 27] FULL
          Length = 367

 Score =  602 bits (1552), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 288/353 (81%), Positives = 325/353 (92%), Gaps = 1/353 (0%)

Query: 19  AARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFIDLYAGFQTFQETGKALPD 78
           +A KSLTIGLIPGDGIG+EVIPAGK VLENL+SKHGL FNFIDL AG+QTF +TGKALPD
Sbjct: 16  SATKSLTIGLIPGDGIGREVIPAGKLVLENLSSKHGLKFNFIDLEAGWQTFLDTGKALPD 75

Query: 79  ETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLFANVRPVKSVEGSRNKPID 138
           ET+++LK +CQGALFGAVQSPT KVEGYSSPIVALR+++GL+ANVRPVKSV  S+ KPID
Sbjct: 76  ETIDILKNECQGALFGAVQSPTNKVEGYSSPIVALRKKLGLYANVRPVKSVL-SQEKPID 134

Query: 139 MVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALKRLQTRGE 198
           MVIVRENTEDLYIK EKTYID+ TGTRVA+A KRISE+ATR IA IAL+IAL+R +  G 
Sbjct: 135 MVIVRENTEDLYIKTEKTYIDEKTGTRVAEAIKRISEVATRNIANIALEIALQRQKVNGS 194

Query: 199 ATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFREPQCFDV 258
           ATLTVTHKSNVLSQ+DGLFREIC++VYESN+DK+G I YNEQIVDSMVYRLFREP+CFDV
Sbjct: 195 ATLTVTHKSNVLSQSDGLFREICRQVYESNQDKFGSINYNEQIVDSMVYRLFREPECFDV 254

Query: 259 IVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCHGSAPDIAGKGIANPIATIR 318
           IVAPNLYGDILSDGAAALVGSLGVVPSANVG + V+GEPCHGSAPDIAGKGI+NP+ATIR
Sbjct: 255 IVAPNLYGDILSDGAAALVGSLGVVPSANVGFDFVVGEPCHGSAPDIAGKGISNPVATIR 314

Query: 319 STALMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKASTQQVVDDVLSRL 371
           STALMLEF+GH  AAQDI+KAVDANLR+  + TPDLGGK++TQQVVDDVLSR+
Sbjct: 315 STALMLEFMGHPEAAQDIHKAVDANLRDNTVKTPDLGGKSTTQQVVDDVLSRM 367

>SAKL0E07656g Chr5 (620028..621134) [1107 bp, 368 aa] {ON} highly
           similar to uniprot|P40495 Saccharomyces cerevisiae
           YIL094C LYS12 Homo-isocitrate dehydrogenase an
           NAD-linked mitochondrial enzyme required for the fourth
           step in the biosynthesis of lysine in which homo-
           isocitrate is oxidatively decarboxylated to alpha-
           ketoadipate
          Length = 368

 Score =  596 bits (1536), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 286/371 (77%), Positives = 329/371 (88%), Gaps = 3/371 (0%)

Query: 1   MFRSVATRVSACRGLATNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFI 60
           M RS  ++  A R  A+  A K LTIGLIPGDGIGKEVIPAGK VLENL+SKH L FNFI
Sbjct: 1   MLRSTVSQF-ARRSYAS--AAKPLTIGLIPGDGIGKEVIPAGKLVLENLSSKHNLKFNFI 57

Query: 61  DLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLF 120
           DL AG+QTF +TGKALPDET+ +LK  CQGALFGAVQSPT KVEGYSSPIVALR+++GL+
Sbjct: 58  DLQAGWQTFLDTGKALPDETIEILKSDCQGALFGAVQSPTNKVEGYSSPIVALRKKLGLY 117

Query: 121 ANVRPVKSVEGSRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRR 180
           ANVRPVKSV+G+ ++P+DM+IVRENTEDLYIK EKTYID+ TGTRVA+A KRISE AT  
Sbjct: 118 ANVRPVKSVQGTNDRPVDMIIVRENTEDLYIKTEKTYIDEKTGTRVAEAIKRISETATTD 177

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQ 240
           IA IAL+I+L+RL+  G+ATLTVTHKSNVLSQ+DGLFRE+CK VYESNK++YG I YNEQ
Sbjct: 178 IAKIALEISLQRLKANGKATLTVTHKSNVLSQSDGLFREVCKNVYESNKERYGAIGYNEQ 237

Query: 241 IVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCHG 300
           IVDSMVYRLFREP+CFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVG + ++GEPCHG
Sbjct: 238 IVDSMVYRLFREPECFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGHDFIVGEPCHG 297

Query: 301 SAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKAST 360
           SAPDIAGKGI+NPIATIRSTALMLEF+G+  AAQDI+KAVD N+RE  I TPDLGGK++T
Sbjct: 298 SAPDIAGKGISNPIATIRSTALMLEFMGYTEAAQDIHKAVDTNIRENQIKTPDLGGKSTT 357

Query: 361 QQVVDDVLSRL 371
           QQVVDD+LS++
Sbjct: 358 QQVVDDILSKM 368

>Kpol_1003.39 s1003 complement(96083..97195) [1113 bp, 370 aa] {ON}
           complement(96083..97195) [1113 nt, 371 aa]
          Length = 370

 Score =  592 bits (1525), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 278/371 (74%), Positives = 331/371 (89%), Gaps = 1/371 (0%)

Query: 1   MFRSVATRVSACRGLATNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFI 60
           M R+   R  A R +  N AR +LTIGLIPGDGIGKEVIPAGK+VLE +  K+ + F FI
Sbjct: 1   MLRNGVYRACARRTV-VNGARSNLTIGLIPGDGIGKEVIPAGKKVLETIGDKYSIDFKFI 59

Query: 61  DLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLF 120
           DL+AG+QTF +TGKALPDETV++LK+QCQGALFGAVQSPTTKVEGYSSPIVALR+++GL+
Sbjct: 60  DLHAGWQTFLDTGKALPDETVSILKQQCQGALFGAVQSPTTKVEGYSSPIVALRKQLGLY 119

Query: 121 ANVRPVKSVEGSRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRR 180
           AN+RPVKSV G+ ++P+DMVIVRENTEDLYIK E+TYID+ATGT+VA+ATKRISE+ATR+
Sbjct: 120 ANIRPVKSVSGTNDRPVDMVIVRENTEDLYIKEERTYIDEATGTKVAEATKRISEVATRK 179

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQ 240
           IA IALDIAL+RL+  G+ATLTVTHKSNVLSQ+DGLFRE+C++VYE NKD YG + YNEQ
Sbjct: 180 IAKIALDIALQRLKNTGKATLTVTHKSNVLSQSDGLFREVCRDVYEKNKDLYGNVSYNEQ 239

Query: 241 IVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCHG 300
           IVDSMVYR+FREP+CFDV+VAPNLYGDILSDGAAALVGSLGVVPSANVGP+I+IGEPCHG
Sbjct: 240 IVDSMVYRIFREPECFDVVVAPNLYGDILSDGAAALVGSLGVVPSANVGPDIIIGEPCHG 299

Query: 301 SAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKAST 360
           SAPDI+G+GI+NP+ATIRS ALML+FLG+N AA+DI  AVD N+R G I TPDLGG +ST
Sbjct: 300 SAPDISGQGISNPVATIRSAALMLQFLGYNEAAKDIQNAVDENIRSGKIKTPDLGGDSST 359

Query: 361 QQVVDDVLSRL 371
            +V DD+LS+L
Sbjct: 360 TEVTDDILSKL 370

>TBLA0B05940 Chr2 complement(1402869..1403978) [1110 bp, 369 aa]
           {ON} Anc_2.287 YIL094C
          Length = 369

 Score =  591 bits (1523), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 286/372 (76%), Positives = 326/372 (87%), Gaps = 4/372 (1%)

Query: 1   MFRSVATRVSACRGLATNAAR-KSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNF 59
           M R+   + S     A NA+  K+LTIGLIPGDGIGKEVIPAGKQVL+NLN KHGL+F F
Sbjct: 1   MLRTSVRQFSVS---ARNASSLKTLTIGLIPGDGIGKEVIPAGKQVLQNLNKKHGLAFEF 57

Query: 60  IDLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGL 119
           IDL AG+QTF +TG ALP +TV++LK +CQGALFGAVQSPTTKVEGYSSPIV LR+E+GL
Sbjct: 58  IDLQAGYQTFLDTGAALPRDTVDILKNKCQGALFGAVQSPTTKVEGYSSPIVQLRKELGL 117

Query: 120 FANVRPVKSVEGSRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATR 179
           FANVRPVK+VEG+  KPID+VIVRENTEDLYIKIEKTY D   G+R+A+ATKRI+E AT+
Sbjct: 118 FANVRPVKTVEGTDAKPIDLVIVRENTEDLYIKIEKTYTDPKDGSRIAEATKRITETATK 177

Query: 180 RIATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNE 239
           RIA  ALDIAL+RL+T+G ATLTVTHKSNVLSQ+DGLFRE+CKEVYESNK  Y  + YNE
Sbjct: 178 RIAKTALDIALQRLKTKGSATLTVTHKSNVLSQSDGLFREVCKEVYESNKSLYSGVAYNE 237

Query: 240 QIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCH 299
           QIVDSMVYRLFREP+CFDVIVAPNLYGDILSDGAAALVGSLG+VPSANVGP IVIGEPCH
Sbjct: 238 QIVDSMVYRLFREPECFDVIVAPNLYGDILSDGAAALVGSLGLVPSANVGPNIVIGEPCH 297

Query: 300 GSAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKAS 359
           GSAPDIAGKGIANPIATIRSTA MLE+LG++  AQDIYKAVDAN+R+  I T DLGG ++
Sbjct: 298 GSAPDIAGKGIANPIATIRSTAQMLEYLGYSNPAQDIYKAVDANIRDNKIKTADLGGDST 357

Query: 360 TQQVVDDVLSRL 371
           TQQV+DD+L +L
Sbjct: 358 TQQVIDDILGKL 369

>TPHA0C03410 Chr3 complement(748639..749754) [1116 bp, 371 aa] {ON}
           Anc_2.287 YIL094C
          Length = 371

 Score =  587 bits (1514), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 287/369 (77%), Positives = 321/369 (86%), Gaps = 1/369 (0%)

Query: 3   RSVATRVSACRGLATNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFIDL 62
           RSV  R    R +   + + +LTIGLIPGDGIGKEVIP+G+QVLE +  KHGL+FNFIDL
Sbjct: 4   RSVYNR-QFQRTIGNISKKSNLTIGLIPGDGIGKEVIPSGRQVLETIGPKHGLTFNFIDL 62

Query: 63  YAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLFAN 122
            AG+QTF +TGKALP ETV  L++ C GALFGAVQSPTTKVEGYSSPIVALR+E+GL+AN
Sbjct: 63  QAGWQTFLDTGKALPVETVKTLRENCDGALFGAVQSPTTKVEGYSSPIVALRKELGLYAN 122

Query: 123 VRPVKSVEGSRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIA 182
           +RPVKSV+   NK +DMVIVRENTEDLYIK+EKTYID+ TGTRVADATKRISE+ATRRIA
Sbjct: 123 IRPVKSVDTPGNKKVDMVIVRENTEDLYIKLEKTYIDEKTGTRVADATKRISEVATRRIA 182

Query: 183 TIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIV 242
            IALDIAL+RL+  G   LTVTHKSNVLSQ+DGLFRE+CKEV+ESNK  Y  I+YNEQI+
Sbjct: 183 KIALDIALQRLKNNGNVQLTVTHKSNVLSQSDGLFREVCKEVFESNKTLYSDIQYNEQII 242

Query: 243 DSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCHGSA 302
           DSMVYRLFREP+CFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGP IVIGEPCHGSA
Sbjct: 243 DSMVYRLFREPECFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPGIVIGEPCHGSA 302

Query: 303 PDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKASTQQ 362
           PDIAGKGI+NPIATIRSTALMLEFLGH+ AAQDI  AVD+NLRE  I TPDLGGK ST  
Sbjct: 303 PDIAGKGISNPIATIRSTALMLEFLGHSQAAQDIQTAVDSNLREDKIKTPDLGGKNSTSD 362

Query: 363 VVDDVLSRL 371
           VV+DV+ RL
Sbjct: 363 VVNDVIRRL 371

>Ecym_3326 Chr3 complement(624805..625905) [1101 bp, 366 aa] {ON}
           similar to Ashbya gossypii ADL214C
          Length = 366

 Score =  544 bits (1402), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 262/355 (73%), Positives = 305/355 (85%), Gaps = 1/355 (0%)

Query: 17  TNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFIDLYAGFQTFQETGKAL 76
           T    KS TIGLIPGDGIGKEVIP G++VLE +  K+G+ F +IDL AG+QTF +TGKAL
Sbjct: 13  TYVTSKSFTIGLIPGDGIGKEVIPVGRKVLEKIGPKYGVDFKYIDLQAGWQTFLDTGKAL 72

Query: 77  PDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLFANVRPVKSVEGSRNKP 136
           PD+TV  L+  CQGALFGAVQSPTTKV+GYSSPIVALR+ +GL+AN+RPVKSV+G+ ++P
Sbjct: 73  PDDTVEQLRNNCQGALFGAVQSPTTKVQGYSSPIVALRKALGLYANIRPVKSVDGTGDRP 132

Query: 137 IDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALKRLQTR 196
           +D+VI RENTEDLYIK E+TYIDK TG RVA+A KRISE ATR IA IAL+IAL+RL+ +
Sbjct: 133 VDLVIARENTEDLYIKSERTYIDKETGGRVAEAIKRISEHATRNIANIALEIALQRLKEK 192

Query: 197 GEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFREPQCF 256
           G ATLTVTHKSNVLSQ+DGLFREICK VY+SNK K+  ++YNEQIVDSMVYRLF+EPQCF
Sbjct: 193 GHATLTVTHKSNVLSQSDGLFREICKSVYQSNK-KFANVQYNEQIVDSMVYRLFKEPQCF 251

Query: 257 DVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCHGSAPDIAGKGIANPIAT 316
           DVIVAPNLYGDILSDGAAALVGSLGVVPS NVGP IVIGEPCHGSAPDI G+GIANPIAT
Sbjct: 252 DVIVAPNLYGDILSDGAAALVGSLGVVPSVNVGPNIVIGEPCHGSAPDIVGQGIANPIAT 311

Query: 317 IRSTALMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKASTQQVVDDVLSRL 371
           IRS AL+LEFLG   AA+ I K VD N+RE  I TPDLGG ++ +QV +D+LSR+
Sbjct: 312 IRSAALLLEFLGLPEAARHIEKVVDENIRENKIKTPDLGGNSTGEQVANDILSRI 366

>ADL214C Chr4 complement(328094..329197) [1104 bp, 367 aa] {ON}
           Syntenic homolog of Saccharomyces cerevisiae YIL094C
           (LYS12)
          Length = 367

 Score =  528 bits (1361), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 256/371 (69%), Positives = 309/371 (83%), Gaps = 4/371 (1%)

Query: 1   MFRSVATRVSACRGLATNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFI 60
           M RS AT +      AT A  K+LTIGLIPGDGIGKEVIPAG++VLE +  KH + F++ 
Sbjct: 1   MHRSSATSLIHK---ATYATSKTLTIGLIPGDGIGKEVIPAGQRVLEAIGKKHDIRFSYE 57

Query: 61  DLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLF 120
            L AG+QTF ETG ALP  TV  L+++CQGALFGAVQSPTTKVEGYSSPIVALRR++GL+
Sbjct: 58  HLDAGWQTFLETGNALPGATVEALRERCQGALFGAVQSPTTKVEGYSSPIVALRRQLGLY 117

Query: 121 ANVRPVKSVEGSRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRR 180
           AN+RPVKSV G+  +P+D+VIVRENTEDLY++ E+TY+D ATG RVA+A KRISE AT R
Sbjct: 118 ANIRPVKSVSGT-GQPVDLVIVRENTEDLYVQQERTYVDAATGKRVAEAIKRISEPATER 176

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQ 240
           IA I+L +AL+R +  G   LTVTHKSNVLSQTDGLF+E+C+EVYE+NK  YG I+YNEQ
Sbjct: 177 IAEISLRLALQRQRMGGRGALTVTHKSNVLSQTDGLFKEVCREVYEANKKSYGSIEYNEQ 236

Query: 241 IVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCHG 300
           IVDSMVYRLF+EP CFDV+VAPNLYGD+LSDGAAALVGSLG+VPS NVG  I+IGEPCHG
Sbjct: 237 IVDSMVYRLFKEPHCFDVVVAPNLYGDLLSDGAAALVGSLGLVPSVNVGNNIIIGEPCHG 296

Query: 301 SAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKAST 360
           SAPDIAG+GIANPIATIRS +LML+FLG   AA DI +AV  NL++  + +PDLGGK +T
Sbjct: 297 SAPDIAGRGIANPIATIRSVSLMLQFLGLEEAASDIDQAVTGNLKDRQVVSPDLGGKNTT 356

Query: 361 QQVVDDVLSRL 371
           Q+V+DD+L+R+
Sbjct: 357 QEVLDDILARI 367

>KLLA0F04103g Chr6 (389159..390244) [1086 bp, 361 aa] {ON}
           uniprot|O94229 Kluyveromyces lactis KLLA0F04103g IDH1
           Isocitrate dehydrogenase subunit 1
          Length = 361

 Score =  188 bits (477), Expect = 8e-56,   Method: Compositional matrix adjust.
 Identities = 129/350 (36%), Positives = 187/350 (53%), Gaps = 25/350 (7%)

Query: 25  TIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFIDLYAGFQTFQETGKALPDETVNVL 84
           T+ LIPGDG+GKEV  +  ++ EN N    + +  ID+ +G +  +   +A     V  L
Sbjct: 31  TVTLIPGDGVGKEVTDSVVKIFENENIP--IDWETIDI-SGLENTENVQRA-----VESL 82

Query: 85  KKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLFANVRPVKSVEG--SRNKPIDMVIV 142
           K+   G L G   +P  +  G+ S  VALR+++ +FANV   KS+ G  +R   IDMVI+
Sbjct: 83  KRNKVG-LKGIWHTPADQT-GHGSLNVALRKQLDIFANVALFKSIPGVKTRLNNIDMVII 140

Query: 143 RENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALKRLQTRGEATLT 202
           RENTE  Y  +E   +       V ++ K ++   + RIA  A D ALK        ++ 
Sbjct: 141 RENTEGEYSGLEHESVPG-----VVESLKIMTRAKSERIARFAFDFALKN----NRKSVC 191

Query: 203 VTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFREPQCFDVIVAP 262
             HK+N++   DGLFR    E+     ++Y ++     IVD+   +   +P  FDV+V P
Sbjct: 192 AVHKANIMKLGDGLFRNTVNEI---GANEYPELDVKNIIVDNASMQAVAKPHQFDVLVTP 248

Query: 263 NLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEP-CHGSAPDIAGKGIANPIATIRSTA 321
           NLYG IL +  +AL+G  G+VP AN G E  + EP       DI G+ +ANP A I S+ 
Sbjct: 249 NLYGSILGNIGSALIGGPGLVPGANFGREYAVFEPGSRHVGLDIKGQNVANPTAMILSST 308

Query: 322 LMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKASTQQVVDDVLSRL 371
           LML  LG N  A  I KA    + EG  TT D+GG AST +  + V+ +L
Sbjct: 309 LMLRHLGLNAYADRISKATYDVISEGKSTTRDIGGSASTSEFTNAVIEKL 358

>ADL223W Chr4 (312893..313981) [1089 bp, 362 aa] {ON} Syntenic
           homolog of Saccharomyces cerevisiae YNL037C (IDH1)
          Length = 362

 Score =  188 bits (477), Expect = 9e-56,   Method: Compositional matrix adjust.
 Identities = 136/383 (35%), Positives = 198/383 (51%), Gaps = 36/383 (9%)

Query: 1   MFRSVATRVSACRGLATNAARKSL---------TIGLIPGDGIGKEVIPAGKQVLENLNS 51
           MFR+  + ++  RG A  A R+ L         T+ LIPGDGIGKEV  +  Q+ E  N 
Sbjct: 1   MFRNTLSHITK-RGYA--AGREQLLPKKYGGRYTVTLIPGDGIGKEVTDSVVQIFEAENV 57

Query: 52  KHGLSFNFIDLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIV 111
              + +  ++L A  +  +   KA     V  LK+   G L G   +P  +  G+ S  V
Sbjct: 58  P--VDWESVELSALEENHEGVQKA-----VESLKRNKVG-LKGIWHTPADQT-GHGSLNV 108

Query: 112 ALRREMGLFANVRPVKSVEGSRNK--PIDMVIVRENTEDLYIKIEKTYIDKATGTRVADA 169
           A R+++ +FANV   KS  G + K   +D+VI+RENTE  Y  +E   +       V ++
Sbjct: 109 AFRKQLDIFANVALFKSFPGVKTKLQDVDLVIIRENTEGEYSGLEHESVPG-----VVES 163

Query: 170 TKRISEIATRRIATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNK 229
            K +++  + RIA  A D ALK         +   HK+N++   DGLFR    E+     
Sbjct: 164 LKIMTKAKSERIARFAFDFALKN----NRKAVCAVHKANIMKLGDGLFRNTVSEI---GA 216

Query: 230 DKYGQIKYNEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVG 289
            +Y ++  +  IVD+   +   +P  FDV+V PNLYG IL +  AAL+G  G+VP AN G
Sbjct: 217 KEYPEVNVSSIIVDNASMQAVAKPHQFDVLVTPNLYGSILGNIGAALIGGPGLVPGANFG 276

Query: 290 PEIVIGEP-CHGSAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGA 348
            E  + EP C     DI G+ +ANP A I S+ LML  LG N  A  I +A    + EG 
Sbjct: 277 REYAVFEPGCRHVGLDIKGQDVANPTAMILSSTLMLRHLGLNEYADRISRATYETIAEGK 336

Query: 349 ITTPDLGGKASTQQVVDDVLSRL 371
            TT D+GG A+T +  + V+ +L
Sbjct: 337 RTTKDIGGTATTTEFTNAVIDKL 359

>NDAI0C01410 Chr3 complement(295178..296287) [1110 bp, 369 aa] {ON}
           Anc_5.473
          Length = 369

 Score =  187 bits (476), Expect = 1e-55,   Method: Compositional matrix adjust.
 Identities = 139/390 (35%), Positives = 199/390 (51%), Gaps = 40/390 (10%)

Query: 1   MFRSVATRVSACRGLAT-------------NAARKSLTIGLIPGDGIGKEVIPAGKQVLE 47
           MFR++  R +  R L+              N +    T+  I GDGIG E+  + KQ+ +
Sbjct: 1   MFRNIILRNTTRRFLSVKNQPSIGKFTGKPNPSTGKFTVSFIEGDGIGPEISQSVKQIFD 60

Query: 48  NLNSKHGLSFNFIDLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYS 107
              +K  + +   D+   F     T   +P+  V  + K    AL G + +P  K  G+ 
Sbjct: 61  A--AKVPIDWEPCDVSPLFINGLTT---IPEPAVQSINKNLV-ALKGPLATPIGK--GHR 112

Query: 108 SPIVALRREMGLFANVRPVKSVEGSRN--KPIDMVIVRENTEDLYIKIEKTYIDKATGTR 165
           S  + LR+  GLFANVRP KS+EG +     +D+VI+RENTE  Y  IE           
Sbjct: 113 SLNLTLRKTFGLFANVRPAKSIEGFKTIYDNVDLVIIRENTEGEYSGIEHVVTPG----- 167

Query: 166 VADATKRISEIATRRIATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVY 225
           V  + K I+  A+ R+   A + A    +  G   + V HKS +    DGLF ++ KE+ 
Sbjct: 168 VVQSIKLITRDASERVIRYAYEYA----RAIGRPRVIVVHKSTIQRLADGLFVDVAKELS 223

Query: 226 ESNKDKYGQIKYNEQIVDSMVYRLFREPQCFD--VIVAPNLYGDILSDGAAAL-VGSLGV 282
           +    +Y  I+   +++D+ V  +   P  +   V V PNLYGDILSD  + L  GSLG+
Sbjct: 224 Q----EYPDIQLETELIDNTVLNVVSNPSSYSNAVSVCPNLYGDILSDLNSGLSAGSLGL 279

Query: 283 VPSANVGPEIVIGEPCHGSAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDA 342
            PSAN+G E+ I E  HGSAPDIAG+  ANP A + S+ +ML  +G N  A  I KAV +
Sbjct: 280 TPSANIGHEVSIFEAVHGSAPDIAGQNKANPTALLLSSVMMLNHMGLNNHADKIEKAVLS 339

Query: 343 NLREGAI-TTPDLGGKASTQQVVDDVLSRL 371
            +  G    T DL GKA+T    D V+ RL
Sbjct: 340 TIASGPEGRTGDLAGKATTSSFTDAVIGRL 369

>Kwal_23.5012 s23 (964254..965339) [1086 bp, 361 aa] {ON} YNL037C
           (IDH1) - alpha-4-beta-4 subunit of mitochondrial
           isocitrate dehydrogenase 1 [contig 7] FULL
          Length = 361

 Score =  186 bits (472), Expect = 4e-55,   Method: Compositional matrix adjust.
 Identities = 134/370 (36%), Positives = 195/370 (52%), Gaps = 33/370 (8%)

Query: 13  RGLATNAARKSL--------TIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFIDLYA 64
           R LAT AA + L        T+ LIPGDG+GKEV  +   + E+ N    + +  +++ +
Sbjct: 11  RSLATMAAEQLLPKKYGGRYTVTLIPGDGVGKEVTDSVVSIFESENIP--IDWETVEI-S 67

Query: 65  GFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLFANVR 124
           G    +   KA     V  LK+   G L G   +P+ +  G+ S  VALR+++ +FANV 
Sbjct: 68  GLDNQEGVQKA-----VESLKRNKVG-LKGIWHTPSDQT-GHGSLNVALRKQLDIFANVA 120

Query: 125 PVKSVEG--SRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIA 182
             KSV G  SR+  +DMV++RENTE  Y  +E   +       V ++ K +++  + RI 
Sbjct: 121 LFKSVPGVPSRHSNVDMVVIRENTEGEYSGLEHESVPG-----VVESLKIMTKAKSERIG 175

Query: 183 TIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIV 242
             A D A+K        ++   HK+N++   DGLFR    EV      +Y +I     IV
Sbjct: 176 RFAFDFAVKN----NRKSVCAVHKANIMKLGDGLFRNCINEV---GAKEYPEIDVKNIIV 228

Query: 243 DSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEP-CHGS 301
           D+   +   +P  FDV+V PNLYG IL +  AAL+G  G+VP AN G E  + EP     
Sbjct: 229 DNASMQAVAKPHQFDVLVTPNLYGSILGNIGAALIGGPGLVPGANFGREYAVFEPGSRHV 288

Query: 302 APDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKASTQ 361
             DI G+ +ANP A I S++LML  LG N  A  I KA    + E   TT D+GG AST 
Sbjct: 289 GLDIKGQNVANPTAMILSSSLMLRHLGLNAYADRISKATYDVIAEAKTTTQDIGGSASTT 348

Query: 362 QVVDDVLSRL 371
           +  + ++S+L
Sbjct: 349 EFTEAIISKL 358

>SAKL0E07876g Chr5 complement(635705..636790) [1086 bp, 361 aa] {ON}
           highly similar to uniprot|P28834 Saccharomyces
           cerevisiae YNL037C IDH1 Subunit of mitochondrial NAD( )-
           dependent isocitrate dehydrogenase which catalyzes the
           oxidation of isocitrate to alpha-ketoglutarate in the
           TCA cycle
          Length = 361

 Score =  186 bits (471), Expect = 6e-55,   Method: Compositional matrix adjust.
 Identities = 141/382 (36%), Positives = 197/382 (51%), Gaps = 35/382 (9%)

Query: 1   MFRSVATRVSACRGLATNAARKSL--------TIGLIPGDGIGKEVIPAGKQVLENLNSK 52
           MFR+  T   + R LAT A  + L        T+ LIPGDG+GKEV  +   + E  N  
Sbjct: 1   MFRN--TFAVSKRSLATVATEQLLPKKYGGRYTVTLIPGDGVGKEVTDSVVSIFEAENVP 58

Query: 53  HGLSFNFIDLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVA 112
             + +  I++  G  + +   KA     V  LK+   G L G   +P  +  G+ S  VA
Sbjct: 59  --IDWETINI-TGVDSEEGVQKA-----VESLKRNKIG-LKGIWHTPADQT-GHGSLNVA 108

Query: 113 LRREMGLFANVRPVKSVEGSRNK--PIDMVIVRENTEDLYIKIEKTYIDKATGTRVADAT 170
            R+++ +FANV   K+V G + K   ID+V++RENTE  Y  +E   +       V ++ 
Sbjct: 109 FRKQLDIFANVALFKNVPGVKTKLSNIDLVVIRENTEGEYSGLEHESVPG-----VVESL 163

Query: 171 KRISEIATRRIATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKD 230
           K I++  + RIA  A D ALK        ++   HK+N++   DGLFR    EV  S   
Sbjct: 164 KIITKAKSERIARFAFDFALKN----NRKSVCAVHKANIMKLGDGLFRNTVNEVGAS--- 216

Query: 231 KYGQIKYNEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGP 290
           +Y +I     IVD+   +   +P  FDV+V PNLYG IL +  AAL+G  G+VP AN G 
Sbjct: 217 EYPEIDVKNIIVDNASMQAVAKPHQFDVLVTPNLYGSILGNIGAALIGGPGLVPGANFGR 276

Query: 291 EIVIGEP-CHGSAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAI 349
           E  + EP       DI GK +ANP A I S+ LML  LG NG A  I KA    + EG  
Sbjct: 277 EYAVFEPGSRHVGLDIKGKDLANPTAMILSSTLMLRHLGLNGYADRISKATYDVIAEGKH 336

Query: 350 TTPDLGGKASTQQVVDDVLSRL 371
           TT D+GG +ST +    V+ +L
Sbjct: 337 TTKDIGGSSSTTEFTKSVIDKL 358

>TPHA0D01560 Chr4 complement(321751..322833) [1083 bp, 360 aa] {ON}
           Anc_2.278 YNL037C
          Length = 360

 Score =  185 bits (470), Expect = 8e-55,   Method: Compositional matrix adjust.
 Identities = 131/352 (37%), Positives = 187/352 (53%), Gaps = 29/352 (8%)

Query: 25  TIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNF--IDLYAGFQTFQETGKALPDETVN 82
           T+ LIPGDGIGKEV  +  ++     +  GL  ++  ID+  G     E  KA     V 
Sbjct: 30  TVTLIPGDGIGKEVTDSVVKIF----ASQGLPIDWERIDV-PGMSNENEVKKA-----VE 79

Query: 83  VLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLFANVRPVKSVEGSRNK--PIDMV 140
            LK+   G     +   +    GY S  VALR+++ +FANV   KS++G + K   +D+V
Sbjct: 80  SLKRNKIG--LKGIWHTSADQTGYGSLNVALRKQLDIFANVAIFKSLKGVKTKIPDVDLV 137

Query: 141 IVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALKRLQTRGEAT 200
           ++RENTE  Y  +E   +       V ++ K I++  T RIA  A D AL+       +T
Sbjct: 138 VIRENTEGEYSGLEHESVPG-----VVESLKIITKPKTERIARFAFDFALEN----NRST 188

Query: 201 LTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFREPQCFDVIV 260
           +T  HK+N++  +DGLF+    EV E    +Y  IK N  IVD+   +   +P  FDV+V
Sbjct: 189 VTAVHKANIMKLSDGLFKNTVAEVGEK---EYPDIKVNTIIVDNASMQAVAKPHQFDVMV 245

Query: 261 APNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEP-CHGSAPDIAGKGIANPIATIRS 319
            P++YG IL +  AAL+G  G++P AN G E  + EP       DI  + IANP A I S
Sbjct: 246 TPSMYGTILGNIGAALIGGPGLIPGANYGREHAVFEPGSRHVGLDIENQNIANPTAMILS 305

Query: 320 TALMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKASTQQVVDDVLSRL 371
             LML  LG    ++ I  AV A + EG  TT D+GG AST +  D V+ +L
Sbjct: 306 ATLMLNQLGLREESKRISNAVYAVIEEGKTTTKDIGGNASTTEFTDAVIDKL 357

>KLLA0E03125g Chr5 (288825..289931) [1107 bp, 368 aa] {ON} highly
           similar to uniprot|P28241 Saccharomyces cerevisiae
           YOR136W IDH2 Subunit of mitochondrial NAD( )- dependent
           isocitrate dehydrogenase which catalyzes the oxidation
           of isocitrate to alpha-ketoglutarate in the TCA cycle
          Length = 368

 Score =  184 bits (466), Expect = 4e-54,   Method: Compositional matrix adjust.
 Identities = 141/395 (35%), Positives = 201/395 (50%), Gaps = 51/395 (12%)

Query: 1   MFRSVATRVSACRGLAT-------------NAARKSLTIGLIPGDGIGKEVIPAGKQVLE 47
           MFR    + S CR LAT             N      T+  I GDG+G E+  + K +  
Sbjct: 1   MFRQSIVKQS-CRFLATKKQPSIGRYTGKPNPKTGKYTVSFIEGDGVGPEISKSVKAIFS 59

Query: 48  NLNSKHGLSFNFIDLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYS 107
              +K  + +   D+   F     T   +PD  V  + K    AL G + +P  K  G+ 
Sbjct: 60  A--AKVPIEWESCDVSPIFVNGLTT---IPDPAVASINKNLI-ALKGPLATPIGK--GHR 111

Query: 108 SPIVALRREMGLFANVRPVKSVEGSRN--KPIDMVIVRENTEDLYIKIEKTYIDKATGTR 165
           S  + LR+  GLFANVRP KS+EG +   + +++V++RENTE  Y  IE      A G  
Sbjct: 112 SLNLTLRKTFGLFANVRPAKSIEGYKTTYENVNLVLIRENTEGEYSGIEHVV---APG-- 166

Query: 166 VADATKRISEIATRRIATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVY 225
           V  + K I++ A+ R+   A + A    +    + + V HKS +    DGLF ++ K++ 
Sbjct: 167 VVQSIKLITQDASERVIRYAFEYA----RAVDRSKVLVVHKSTIQRLADGLFVDVAKKL- 221

Query: 226 ESNKDKYGQIKYNEQIVDSMVYRLFREPQCFD--VIVAPNLYGDILSDGAAAL-VGSLGV 282
                +Y  I+   +++D+ V +  + P+ +D  V+V PNLYGDILSD  + L  GSLG+
Sbjct: 222 ---SSEYPDIELQTELLDNTVLKTVQHPEAYDDVVVVCPNLYGDILSDLNSGLSAGSLGL 278

Query: 283 VPSANVGPEIVIGEPCHGSAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAV-- 340
            PSAN+G  + I E  HGSAPDIAG+  ANP A + S+ +ML  +G    A  I KAV  
Sbjct: 279 TPSANIGHTVSIFEAVHGSAPDIAGQNKANPTALLLSSVMMLNHMGLTEHADKIEKAVLT 338

Query: 341 ----DANLREGAITTPDLGGKASTQQVVDDVLSRL 371
               DA  R G     DLGG AST    D V+ RL
Sbjct: 339 TIASDAKNRTG-----DLGGSASTSSFTDAVIERL 368

>Smik_15.316 Chr15 (541618..542727) [1110 bp, 369 aa] {ON} YOR136W
           (REAL)
          Length = 369

 Score =  180 bits (457), Expect = 9e-53,   Method: Compositional matrix adjust.
 Identities = 137/390 (35%), Positives = 194/390 (49%), Gaps = 40/390 (10%)

Query: 1   MFRSVATRVSACRGLAT-------------NAARKSLTIGLIPGDGIGKEVIPAGKQVLE 47
           M R+   R ++ R LAT             N +    T+  I GDGIG E+  + K++  
Sbjct: 1   MLRNTFFRNTSRRFLATVKQPSIGKYTGKPNPSTGKYTVSFIEGDGIGPEISKSVKKIFS 60

Query: 48  NLNSKHGLSFNFIDLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYS 107
             N    + + F D+   F     T   +PD  V  + K    AL G + +P  K  G+ 
Sbjct: 61  AANVP--IEWEFCDVNPIFVNGLTT---IPDPAVQSITKNLV-ALKGPLATPIGK--GHR 112

Query: 108 SPIVALRREMGLFANVRPVKSVEGSRN--KPIDMVIVRENTEDLYIKIEKTYIDKATGTR 165
           S  + LR+  GLFANVRP KSVEG +   + +D+V++RENTE  Y  IE           
Sbjct: 113 SLNLTLRKTFGLFANVRPAKSVEGFKTTYENVDLVLIRENTEGEYSGIEHIVCPG----- 167

Query: 166 VADATKRISEIATRRIATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVY 225
           V  + K I+  A+ R+   A + A    +  G   + V HKS +    DGLF  + KE+ 
Sbjct: 168 VVQSIKLITRDASERVIRYAFEYA----RAIGRPRVIVVHKSTIQRLADGLFVNVAKEL- 222

Query: 226 ESNKDKYGQIKYNEQIVDSMVYRLFREPQCFD--VIVAPNLYGDILSDGAAAL-VGSLGV 282
                +Y  I    +++D+ V ++   P  +   V V PNLYGDILSD  + L  GSLG+
Sbjct: 223 ---SKEYPDITLETELIDNSVLKVVTNPSAYTNAVSVCPNLYGDILSDLNSGLSAGSLGL 279

Query: 283 VPSANVGPEIVIGEPCHGSAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDA 342
            PSAN+G +I I E  HGSAPDIAG+  ANP A + S+ +ML  +G    A  I  AV +
Sbjct: 280 TPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNYADQIQNAVLS 339

Query: 343 NLREGAIT-TPDLGGKASTQQVVDDVLSRL 371
            +  G    T DL G A+T    + V+ RL
Sbjct: 340 TIASGPENRTGDLAGAATTSSFTEAVIKRL 369

>Ecym_3316 Chr3 (608744..609832) [1089 bp, 362 aa] {ON} similar to
           Ashbya gossypii ADL223W
          Length = 362

 Score =  180 bits (456), Expect = 1e-52,   Method: Compositional matrix adjust.
 Identities = 126/350 (36%), Positives = 182/350 (52%), Gaps = 24/350 (6%)

Query: 25  TIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFIDLYAGFQTFQETGKALPDETVNVL 84
           T+ LIPGDG+GKEV  +   + E  N    + +  ++L    +  +   KA     V  L
Sbjct: 31  TVTLIPGDGVGKEVTDSVVNIFEAENVP--IDWESVELSGLEENMEGVQKA-----VESL 83

Query: 85  KKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLFANVRPVKSVEGSRNK--PIDMVIV 142
           K+   G L G   +P  +  G+ S  VA R+++ +FANV   KS  G + K   +D+VI+
Sbjct: 84  KRNKVG-LKGIWSTPADQT-GHGSLNVAFRKQLDIFANVALFKSFPGVKTKLKDVDLVII 141

Query: 143 RENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALKRLQTRGEATLT 202
           RENTE  Y  +E   +       V ++ K +++  + RIA  A D ALK        ++ 
Sbjct: 142 RENTEGEYSGLEHESVPG-----VVESLKIMTKAKSERIARFAFDFALKN----NRRSVC 192

Query: 203 VTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFREPQCFDVIVAP 262
             HK+N++   DGLFR    E+      +Y +++    IVD+   +   +P  FDV+V P
Sbjct: 193 AVHKANIMKLGDGLFRNTVNEI---GAKEYPELEVKSIIVDNASMQAVAKPHQFDVLVTP 249

Query: 263 NLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEP-CHGSAPDIAGKGIANPIATIRSTA 321
           NLYG IL +  AAL+GS G+VP AN G E  + EP       DI G+ +ANP A I S+ 
Sbjct: 250 NLYGSILGNVGAALIGSPGLVPGANFGREYAVFEPGSRHVGLDIKGQDVANPTAMILSST 309

Query: 322 LMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKASTQQVVDDVLSRL 371
           LML  LG N  A  I KA    + EG  TT D+GG AST Q    ++ +L
Sbjct: 310 LMLRHLGLNDYADRISKATYEVIAEGKHTTKDIGGHASTTQFTKAIVDKL 359

>NCAS0H02250 Chr8 (441692..442960) [1269 bp, 422 aa] {ON} Anc_5.473
          Length = 422

 Score =  181 bits (459), Expect = 1e-52,   Method: Compositional matrix adjust.
 Identities = 134/390 (34%), Positives = 197/390 (50%), Gaps = 40/390 (10%)

Query: 1   MFRSVATRVSACRGLAT-------------NAARKSLTIGLIPGDGIGKEVIPAGKQVLE 47
           MFRS   R +  R L+              N +    T+  I GDGIG E+  + KQ+  
Sbjct: 54  MFRSSILRTTTRRLLSVKHQPSIGKYTGKPNPSTGKYTVSFIEGDGIGPEISNSVKQIFS 113

Query: 48  NLNSKHGLSFNFIDLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYS 107
              +K  + +   D+      F +    +P+  V  + K    AL G + +P  K  G+ 
Sbjct: 114 A--AKVPIEWETCDVTP---LFIDGLTTIPEPAVQSINKNLV-ALKGPLATPIGK--GHR 165

Query: 108 SPIVALRREMGLFANVRPVKSVEGSRN--KPIDMVIVRENTEDLYIKIEKTYIDKATGTR 165
           S  + LR+  GLFANVRP +SV+G +     +D+V++RENTE  Y  IE           
Sbjct: 166 SLNLTLRKTFGLFANVRPARSVKGFKTTYPNVDLVLIRENTEGEYSGIEHVVTPG----- 220

Query: 166 VADATKRISEIATRRIATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVY 225
           V  + K I+  A+ R+    +  A +  +  G   L V HKS +   +DGLF  + KE+ 
Sbjct: 221 VVQSIKLITREASERV----IRYAFEYCRAIGRPRLVVVHKSTIQRLSDGLFVNVAKEL- 275

Query: 226 ESNKDKYGQIKYNEQIVDSMVYRLFREPQCFD--VIVAPNLYGDILSDGAAAL-VGSLGV 282
                +Y  I++  +++D+ V ++   P  +   V V PNLYGDILSD  + L  GSLG+
Sbjct: 276 ---SKEYPDIQFETELIDNTVLKVVSNPSSYTDAVSVCPNLYGDILSDLNSGLSAGSLGL 332

Query: 283 VPSANVGPEIVIGEPCHGSAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDA 342
            PS N+G EI I E  HGSAPDIAGK +ANP A + S+ +ML  +G +  A  I  AV +
Sbjct: 333 TPSGNIGNEISIFEAVHGSAPDIAGKNMANPTALLLSSVMMLNHMGLSKHADQIENAVLS 392

Query: 343 NLREGAIT-TPDLGGKASTQQVVDDVLSRL 371
            +  G  + T DL G A+T    D V+ +L
Sbjct: 393 TIASGPESRTGDLAGTATTSTFTDAVIKKL 422

>KLTH0G10186g Chr7 (863151..864233) [1083 bp, 360 aa] {ON} highly
           similar to uniprot|P28834 Saccharomyces cerevisiae
           YNL037C IDH1 Subunit of mitochondrial NAD( )- dependent
           isocitrate dehydrogenase which catalyzes the oxidation
           of isocitrate to alpha-ketoglutarate in the TCA cycle
          Length = 360

 Score =  179 bits (454), Expect = 2e-52,   Method: Compositional matrix adjust.
 Identities = 125/350 (35%), Positives = 186/350 (53%), Gaps = 25/350 (7%)

Query: 25  TIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFIDLYAGFQTFQETGKALPDETVNVL 84
           T+ LIPGDG+GKEV  +   + E+ N    + +  +++ +G    +   KA     V+ L
Sbjct: 30  TVTLIPGDGVGKEVTDSVVSIFESENVP--IDWETVEI-SGLDNEEGVQKA-----VDSL 81

Query: 85  KKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLFANVRPVKSVEG--SRNKPIDMVIV 142
           K+   G L G   +P+ +  G+ S  VALR+++ +FANV   K+V G  SR+  +D+V++
Sbjct: 82  KRNKVG-LKGIWHTPSDQT-GHGSLNVALRKQLDIFANVALFKTVPGVPSRHSNVDLVVI 139

Query: 143 RENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALKRLQTRGEATLT 202
           RENTE  Y  +E   +       V ++ K +++  + RI   A D ALK        ++ 
Sbjct: 140 RENTEGEYSGLEHESVPG-----VVESLKIMTKAKSDRIGRFAFDFALKN----NRKSVC 190

Query: 203 VTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFREPQCFDVIVAP 262
             HK+N++   DGLFR    E+      +Y +I+    IVD+   +   +P  FDV+V P
Sbjct: 191 AVHKANIMKLGDGLFRNCINEI---GAKEYPEIEVKNIIVDNASMQAVAKPHQFDVLVTP 247

Query: 263 NLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEP-CHGSAPDIAGKGIANPIATIRSTA 321
           NLYG IL +  AAL+G  G+VP AN G E  + EP       DI G+ +ANP A I S+A
Sbjct: 248 NLYGSILGNIGAALIGGPGLVPGANFGREFAVFEPGSRHVGLDIKGQNVANPTAMILSSA 307

Query: 322 LMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKASTQQVVDDVLSRL 371
           LML  LG N  A  I KA    + E   TT D+GG AST      ++ +L
Sbjct: 308 LMLRHLGLNSYADRISKATYDVIAEAKNTTKDIGGSASTTDFTQAIIEKL 357

>Suva_8.188 Chr8 (335409..336518) [1110 bp, 369 aa] {ON} YOR136W
           (REAL)
          Length = 369

 Score =  178 bits (452), Expect = 5e-52,   Method: Compositional matrix adjust.
 Identities = 127/353 (35%), Positives = 183/353 (51%), Gaps = 27/353 (7%)

Query: 25  TIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFIDLYAGFQTFQETGKALPDETVNVL 84
           T+  I GDGIG E+  + K++    +    +++ F D+   F     T   +PD  V  +
Sbjct: 38  TVSFIEGDGIGPEISKSVKKIFSAADVP--INWEFCDVNPIFVNGLTT---IPDPAVQSI 92

Query: 85  KKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLFANVRPVKSVEGSRN--KPIDMVIV 142
            K    AL G + +P  K  G+ S  + LR+  GLFANVRP KS+EG +   + +D+V++
Sbjct: 93  TKNLV-ALKGPLATPIGK--GHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYENVDLVLI 149

Query: 143 RENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALKRLQTRGEATLT 202
           RENTE  Y  IE           V  + K I+  A+ R+   A + A    +  G   + 
Sbjct: 150 RENTEGEYSGIEHIVCPG-----VVQSIKLITREASERVIRYAFEYA----RAIGRPRII 200

Query: 203 VTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFREPQCFD--VIV 260
           V HKS +    DGLF  + KE+      +Y  I +  +++D+ V  +   P  +   V V
Sbjct: 201 VVHKSTIQRLADGLFVNVAKEL----SKEYPDITFETELIDNKVLNVVTNPSAYTNAVSV 256

Query: 261 APNLYGDILSDGAAAL-VGSLGVVPSANVGPEIVIGEPCHGSAPDIAGKGIANPIATIRS 319
            PNLYGDILSD  + L  GSLG+ PSAN+G ++ I E  HGSAPDIAGK  ANP A + S
Sbjct: 257 CPNLYGDILSDLNSGLSAGSLGLTPSANIGHKVSIFEAVHGSAPDIAGKDKANPTALLLS 316

Query: 320 TALMLEFLGHNGAAQDIYKAVDANLREGAIT-TPDLGGKASTQQVVDDVLSRL 371
           + +ML  +G    A  I  AV + +  G    T DL G A+T    + V+ RL
Sbjct: 317 SVMMLNHMGLTSHADQIQNAVLSTIASGPENRTGDLAGTATTSSFTEAVIKRL 369

>NCAS0B06290 Chr2 complement(1186838..1187917) [1080 bp, 359 aa]
           {ON} Anc_2.278
          Length = 359

 Score =  177 bits (450), Expect = 6e-52,   Method: Compositional matrix adjust.
 Identities = 130/383 (33%), Positives = 200/383 (52%), Gaps = 39/383 (10%)

Query: 1   MFRSVATRVSACRGLATNAARKS---------LTIGLIPGDGIGKEVIPAGKQVLENLNS 51
           MFR    +  A R LAT   +++         +T+ L+PGDG+GKE+  +   + +  N 
Sbjct: 1   MFR----QTIAKRTLATFIPKETILPKKYGGRMTVTLLPGDGVGKEITDSVVSIFQAENV 56

Query: 52  KHGLSFNFIDLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIV 111
              + +  +D+    Q   E G    +  V  LK+   G L G   +   +V G+ S  V
Sbjct: 57  P--IDWETVDIS---QLDHEDGV---NAAVESLKRNKIG-LKGIWHTSADQV-GHGSLNV 106

Query: 112 ALRREMGLFANVRPVKSVEGSRNK--PIDMVIVRENTEDLYIKIEKTYIDKATGTRVADA 169
           A R+++ ++ANV   KS+ G + K   +D+VI+RENTE  Y  +E   +       V ++
Sbjct: 107 AFRKQLDIYANVAFCKSIPGVKTKIPNVDLVIIRENTEGEYSGLEHESVPG-----VVES 161

Query: 170 TKRISEIATRRIATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNK 229
            K ++++ + RIA  A D A++         +T  HK+N++  +DGLFR     V E+  
Sbjct: 162 LKIVTKVNSERIAKFAFDFAMRH----DRKMVTAVHKANIMKLSDGLFRNTVARVGEA-- 215

Query: 230 DKYGQIKYNEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVG 289
             Y QIK +  IVD+   +   +P  FDV+V P++YG IL +  AAL+G  G+VP  N G
Sbjct: 216 --YPQIKNDSIIVDNASMQAVAKPHQFDVMVTPSMYGTILGNIGAALIGGPGLVPGVNYG 273

Query: 290 PEIVIGEP-CHGSAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGA 348
            E  + EP       DI G+ +ANP A I S+ L+L+ LG N  A  I KAV   ++EG 
Sbjct: 274 REYAVFEPGSRHVGLDIKGQNVANPTAMILSSTLLLQHLGLNDTASRISKAVYDVIKEGN 333

Query: 349 ITTPDLGGKASTQQVVDDVLSRL 371
            TT D+GG AST +    V+ +L
Sbjct: 334 ATTKDIGGNASTTEFTKAVIDKL 356

>YNL037C Chr14 complement(557920..559002) [1083 bp, 360 aa] {ON}
           IDH1Subunit of mitochondrial NAD(+)-dependent isocitrate
           dehydrogenase, which catalyzes the oxidation of
           isocitrate to alpha-ketoglutarate in the TCA cycle
          Length = 360

 Score =  177 bits (450), Expect = 9e-52,   Method: Compositional matrix adjust.
 Identities = 127/372 (34%), Positives = 197/372 (52%), Gaps = 26/372 (6%)

Query: 3   RSVATRVSACRGLATNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFIDL 62
           R++AT   A R L      +  T+ LIPGDG+GKE+  + + + E  N    + +  I++
Sbjct: 9   RTLATAAQAERTLPKKYGGR-FTVTLIPGDGVGKEITDSVRTIFEAENIP--IDWETINI 65

Query: 63  YAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLFAN 122
               QT  + G     E V  LK+   G L G   +P  +  G+ S  VALR+++ ++AN
Sbjct: 66  K---QTDHKEGVY---EAVESLKRNKIG-LKGLWHTPADQT-GHGSLNVALRKQLDIYAN 117

Query: 123 VRPVKSVEGSRNK--PIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRR 180
           V   KS++G + +   ID++++RENTE  +  +E   +       V ++ K ++   T R
Sbjct: 118 VALFKSLKGVKTRIPDIDLIVIRENTEGEFSGLEHESVPG-----VVESLKVMTRPKTER 172

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQ 240
           IA  A D A K        ++T  HK+N++   DGLFR I  E+    + +Y  I  +  
Sbjct: 173 IARFAFDFAKKY----NRKSVTAVHKANIMKLGDGLFRNIITEI---GQKEYPDIDVSSI 225

Query: 241 IVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEP-CH 299
           IVD+   +   +P  FDV+V P++YG IL +  AAL+G  G+V  AN G +  + EP   
Sbjct: 226 IVDNASMQAVAKPHQFDVLVTPSMYGTILGNIGAALIGGPGLVAGANFGRDYAVFEPGSR 285

Query: 300 GSAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKAS 359
               DI G+ +ANP A I S+ LML  LG N  A  I KAV   + EG  TT D+GG +S
Sbjct: 286 HVGLDIKGQNVANPTAMILSSTLMLNHLGLNEYATRISKAVHETIAEGKHTTRDIGGSSS 345

Query: 360 TQQVVDDVLSRL 371
           T    ++++++L
Sbjct: 346 TTDFTNEIINKL 357

>Smik_14.290 Chr14 (528131..529213) [1083 bp, 360 aa] {ON} YNL037C
           (REAL)
          Length = 360

 Score =  177 bits (449), Expect = 1e-51,   Method: Compositional matrix adjust.
 Identities = 128/372 (34%), Positives = 196/372 (52%), Gaps = 26/372 (6%)

Query: 3   RSVATRVSACRGLATNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFIDL 62
           R++AT   A R L      +  T+ LIPGDG+GKE+  + K + E    K  + +  +++
Sbjct: 9   RTLATAAQAERALPKKYGGR-FTVTLIPGDGVGKEITDSVKTIFEA--EKIPVDWETVNI 65

Query: 63  YAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLFAN 122
               QT  + G     E V  LK+   G L G   +P  +  G+ S  VALR+++ ++AN
Sbjct: 66  K---QTDHKEGVY---EAVESLKRNKIG-LKGLWHTPADQT-GHGSLNVALRKQLDIYAN 117

Query: 123 VRPVKSVEG--SRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRR 180
           V   KS++G  +R   ID++++RENTE  +  +E   +       V ++ K ++   T R
Sbjct: 118 VALFKSLKGVKTRIPDIDLIVIRENTEGEFSGLEHESVPG-----VVESLKIMTRPKTER 172

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQ 240
           IA  A D A K         +T  HK+N++   DGLFR I  E+    + +Y  I  +  
Sbjct: 173 IARFAFDFAKKY----NRKAVTAVHKANIMKLGDGLFRNIITEI---GQKEYPDIDVSSI 225

Query: 241 IVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEP-CH 299
           IVD+   +   +P  FDV+V P++YG IL +  AAL+G  G+V  AN G +  + EP   
Sbjct: 226 IVDNASMQAVAKPHQFDVLVTPSMYGTILGNIGAALIGGPGLVAGANFGRDYAVFEPGSR 285

Query: 300 GSAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKAS 359
               DI G+ +ANP A I S+ LML  LG N  A  I KAV   + EG  TT D+GG +S
Sbjct: 286 HVGLDIKGQNVANPTAMILSSVLMLNHLGLNEYATRISKAVHETIAEGKHTTKDIGGSSS 345

Query: 360 TQQVVDDVLSRL 371
           T    ++++++L
Sbjct: 346 TTDFTNEIINKL 357

>KLTH0F15048g Chr6 complement(1232566..1233672) [1107 bp, 368 aa]
           {ON} highly similar to uniprot|P28241 Saccharomyces
           cerevisiae YOR136W IDH2 Subunit of mitochondrial NAD( )-
           dependent isocitrate dehydrogenase which catalyzes the
           oxidation of isocitrate to alpha-ketoglutarate in the
           TCA cycle
          Length = 368

 Score =  177 bits (449), Expect = 1e-51,   Method: Compositional matrix adjust.
 Identities = 139/390 (35%), Positives = 200/390 (51%), Gaps = 41/390 (10%)

Query: 1   MFRSVATRVSACRGLAT-------------NAARKSLTIGLIPGDGIGKEVIPAGKQVLE 47
           MF+S   R SA R LAT             + A    T+  I GDG+G E+  A K +  
Sbjct: 1   MFKSSFVRNSA-RFLATKKQPSIGRYTGKPDPATGKYTVSFIEGDGVGPEISKAVKDIFA 59

Query: 48  NLNSKHGLSFNFIDLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYS 107
              +K  + +   D+   F     T   +P    + + K    AL G + +P  K  G+ 
Sbjct: 60  A--AKAPIQWESCDVSPLFINGLTT---IPQPAQDSINKNLI-ALKGPLATPIGK--GHR 111

Query: 108 SPIVALRREMGLFANVRPVKSVEGSRN--KPIDMVIVRENTEDLYIKIEKTYIDKATGTR 165
           S  + LR+  GLFANVRP KSV+G +     +D+V++RENTE  Y  IE           
Sbjct: 112 SLNLTLRKTFGLFANVRPAKSVQGYKTAYDNVDLVLIRENTEGEYSGIEHV-----VSPG 166

Query: 166 VADATKRISEIATRRIATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVY 225
           V  + K I++ A+ R+   A + A  R   R +  + V HKS +    DGLF  + +++ 
Sbjct: 167 VVQSIKLITQDASERVIRYAFEYA--RAVERPK--VVVVHKSTIQRLADGLFVSVAEQLS 222

Query: 226 ESNKDKYGQIKYNEQIVDSMVYRLFREPQCFD--VIVAPNLYGDILSDGAAAL-VGSLGV 282
           +    +Y  I+   +++D+ V    R+P  +   V+V PNLYGDILSD  + L  GSLG+
Sbjct: 223 K----EYPDIELQTELIDNTVLHTVRDPTKYSDVVVVCPNLYGDILSDMNSGLSAGSLGL 278

Query: 283 VPSANVGPEIVIGEPCHGSAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDA 342
            PSAN+G ++ I E  HGSAPDIAG+  ANP A + S+ +ML  +G    A  I KAV  
Sbjct: 279 TPSANIGHKVSIFEAVHGSAPDIAGQNKANPTALLLSSVMMLNHMGLTEHADKIEKAVFT 338

Query: 343 NLREGAIT-TPDLGGKASTQQVVDDVLSRL 371
            +  G  + T DLGG AST    + V+SRL
Sbjct: 339 TIAAGPESRTGDLGGSASTSSFAEAVISRL 368

>KNAG0B04070 Chr2 complement(778658..779779) [1122 bp, 373 aa] {ON}
           Anc_5.473 YOR136W
          Length = 373

 Score =  177 bits (448), Expect = 2e-51,   Method: Compositional matrix adjust.
 Identities = 131/360 (36%), Positives = 187/360 (51%), Gaps = 27/360 (7%)

Query: 18  NAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFIDLYAGFQTFQETGKALP 77
           N A     +  I GDGIG E+  + K + +   ++  +++ F D+   F     T   +P
Sbjct: 35  NPATGKFDVSFIEGDGIGPEISQSVKDIFKA--AEVPINWEFCDVTPIFVNGLTT---IP 89

Query: 78  DETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLFANVRPVKSVEGSRN--K 135
           D  V  + K    AL G + +P  K  G+ S  + LR+   LFANVRP KS+EG +    
Sbjct: 90  DPAVASINKNLI-ALKGPLATPIGK--GHRSLNLTLRKTFNLFANVRPAKSIEGFKTTYS 146

Query: 136 PIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALKRLQT 195
            +D+V++RENTE  Y  IE      A G  V  + K I+  A+ R+   A + A    + 
Sbjct: 147 DVDLVLIRENTEGEYSGIEHVV---APG--VVQSIKLITRDASERVIRYAFEYA----KA 197

Query: 196 RGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFREPQC 255
            G   + V HKS +    DGLF  + KE+ +    +Y +IK   +++D+ V  +   P  
Sbjct: 198 IGRPRVVVVHKSTIQRLADGLFVNVAKELSK----EYPEIKLETELIDNTVLNVVSNPAG 253

Query: 256 FD--VIVAPNLYGDILSDGAAAL-VGSLGVVPSANVGPEIVIGEPCHGSAPDIAGKGIAN 312
           +   V V PNLYGDILSD  + L  GSLG+ PSAN+G EI I E  HGSAPDIAG+  AN
Sbjct: 254 YTDAVSVCPNLYGDILSDLNSGLSAGSLGLTPSANIGNEISIFEAVHGSAPDIAGQNKAN 313

Query: 313 PIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAIT-TPDLGGKASTQQVVDDVLSRL 371
           P A + S+ +ML  +G    A  I +AV   +   +   T DLGG A+T    D V+  L
Sbjct: 314 PTALLLSSVMMLNHMGLVDQASRIERAVLTTIASSSKNRTGDLGGSATTSSFTDAVIKNL 373

>Skud_14.293 Chr14 (538202..539287) [1086 bp, 361 aa] {ON} YNL037C
           (REAL)
          Length = 361

 Score =  176 bits (446), Expect = 3e-51,   Method: Compositional matrix adjust.
 Identities = 127/372 (34%), Positives = 198/372 (53%), Gaps = 26/372 (6%)

Query: 3   RSVATRVSACRGLATNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFIDL 62
           R++AT   A R L      +  T+ LIPGDG+GKE+  + + + E    +  + +  I++
Sbjct: 9   RTLATAAQAERTLPKKYGGR-FTVTLIPGDGVGKEITDSVRTIFEA--ERIPVDWETINI 65

Query: 63  YAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLFAN 122
               QT  + G     E V  LK+   G L G   +P  +  G+ S  VALR+++ ++AN
Sbjct: 66  K---QTDHKEGVY---EAVESLKRNKIG-LKGLWHTPADQT-GHGSLNVALRKQLDIYAN 117

Query: 123 VRPVKSVEGSRNK--PIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRR 180
           V   KS++G + +   ID++++RENTE  +  +E   +       V ++ K +++  T R
Sbjct: 118 VALFKSLKGVKTRIPDIDLIVIRENTEGEFSGLEHESVPG-----VVESLKVMTKPKTER 172

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQ 240
           IA  A D A K         +T  HK+N++   DGLFR I  E+ ++   +Y  I  +  
Sbjct: 173 IARFAFDFAKKY----NRKAVTAVHKANIMKLGDGLFRNIITEIGQT---EYPDIDVSSI 225

Query: 241 IVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEP-CH 299
           IVD+   +   +P  FDV+V P++YG IL +  AAL+G  G+V  AN G +  + EP   
Sbjct: 226 IVDNASMQAVAKPHQFDVLVTPSMYGTILGNIGAALIGGPGLVAGANFGRDYAVFEPGSR 285

Query: 300 GSAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKAS 359
               DI G+ +ANP A I S+ LML  LG N  A  I KAV   + EG  TT D+GG +S
Sbjct: 286 HVGLDIKGQNVANPTAMILSSVLMLNHLGLNENATRISKAVHETIAEGKHTTRDIGGSSS 345

Query: 360 TQQVVDDVLSRL 371
           T    ++V+++L
Sbjct: 346 TTDFTNEVINKL 357

>TBLA0B02240 Chr2 complement(524111..525232) [1122 bp, 373 aa] {ON}
           Anc_5.473 YOR136W
          Length = 373

 Score =  176 bits (446), Expect = 4e-51,   Method: Compositional matrix adjust.
 Identities = 134/398 (33%), Positives = 200/398 (50%), Gaps = 52/398 (13%)

Query: 1   MFRSVATRVSACRGLAT-----------------NAARKSLTIGLIPGDGIGKEVIPAGK 43
           M R++A + SA R  +T                 N +    T+  I GDG+G E+  + K
Sbjct: 1   MLRTIAAKQSARRLFSTSSTLRVSGQVGKYKGSPNPSTGRFTVPFIEGDGVGPEISKSVK 60

Query: 44  QVLENLNSKHGLSFNFID----LYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSP 99
            + +   ++  + + + D    L  G  T       +P+  V  + K  + AL G + +P
Sbjct: 61  DIFKA--AQVPVDWEYCDVSPLLINGLTT-------IPEPAVQQINKH-KIALKGPLATP 110

Query: 100 TTKVEGYSSPIVALRREMGLFANVRPVKSVEG--SRNKPIDMVIVRENTEDLYIKIEKTY 157
             K  G+ S  + LR+  GLFANVRP +S+ G  +  K +D+V++RENTE  Y  IE   
Sbjct: 111 IGK--GHRSLNLTLRKTFGLFANVRPARSIRGYETTYKNVDLVLIRENTEGEYSGIEHVV 168

Query: 158 IDKATGTRVADATKRISEIATRRIATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLF 217
              A G  V  + K I+  A+ R+   A + A    +  G   L V HKS +    DGLF
Sbjct: 169 ---APG--VVQSIKLITRDASERVIRYAYEYA----RAIGRPRLVVVHKSTIQKLADGLF 219

Query: 218 REICKEVYESNKDKYGQIKYNEQIVDSMVYRLFREPQCFD--VIVAPNLYGDILSDGAAA 275
             I KE+      ++  IK   +++D+ V  + R+P  +   V V PNLYGDILSD  + 
Sbjct: 220 VNIAKEL----APEFPDIKLETELIDNTVLNVVRDPPSYTDAVTVCPNLYGDILSDLNSG 275

Query: 276 L-VGSLGVVPSANVGPEIVIGEPCHGSAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQ 334
           L  GSLG+ PSAN+G E+ I E  HGSAPDIAG+  ANP A + S+ +ML ++G    + 
Sbjct: 276 LSAGSLGLTPSANIGNEVSIFEAVHGSAPDIAGQNKANPTALLLSSCMMLNYMGLESYSN 335

Query: 335 DIYKAVDANLREGAIT-TPDLGGKASTQQVVDDVLSRL 371
            I  A+   +  G+   T DL G A+T    + V+  L
Sbjct: 336 KIENAILNTIASGSENRTGDLAGTATTSSFTESVIKNL 373

>YOR136W Chr15 (580250..581359) [1110 bp, 369 aa] {ON}  IDH2Subunit
           of mitochondrial NAD(+)-dependent isocitrate
           dehydrogenase, which catalyzes the oxidation of
           isocitrate to alpha-ketoglutarate in the TCA cycle;
           phosphorylated
          Length = 369

 Score =  176 bits (445), Expect = 6e-51,   Method: Compositional matrix adjust.
 Identities = 134/390 (34%), Positives = 193/390 (49%), Gaps = 40/390 (10%)

Query: 1   MFRSVATRVSACRGLAT-------------NAARKSLTIGLIPGDGIGKEVIPAGKQVLE 47
           M R+   R ++ R LAT             N +    T+  I GDGIG E+  + K++  
Sbjct: 1   MLRNTFFRNTSRRFLATVKQPSIGRYTGKPNPSTGKYTVSFIEGDGIGPEISKSVKKIFS 60

Query: 48  NLNSKHGLSFNFIDLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYS 107
             N    + +   D+   F     T   +PD  V  + K    AL G + +P  K  G+ 
Sbjct: 61  AANVP--IEWESCDVSPIFVNGLTT---IPDPAVQSITKNLV-ALKGPLATPIGK--GHR 112

Query: 108 SPIVALRREMGLFANVRPVKSVEGSRN--KPIDMVIVRENTEDLYIKIEKTYIDKATGTR 165
           S  + LR+  GLFANVRP KS+EG +   + +D+V++RENTE  Y  IE           
Sbjct: 113 SLNLTLRKTFGLFANVRPAKSIEGFKTTYENVDLVLIRENTEGEYSGIEHIVCPG----- 167

Query: 166 VADATKRISEIATRRIATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVY 225
           V  + K I+  A+ R+   A + A    +  G   + V HKS +    DGLF  + KE+ 
Sbjct: 168 VVQSIKLITRDASERVIRYAFEYA----RAIGRPRVIVVHKSTIQRLADGLFVNVAKEL- 222

Query: 226 ESNKDKYGQIKYNEQIVDSMVYRLFREPQCFD--VIVAPNLYGDILSDGAAAL-VGSLGV 282
                +Y  +    +++D+ V ++   P  +   V V PNLYGDILSD  + L  GSLG+
Sbjct: 223 ---SKEYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGLSAGSLGL 279

Query: 283 VPSANVGPEIVIGEPCHGSAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDA 342
            PSAN+G +I I E  HGSAPDIAG+  ANP A + S+ +ML  +G    A  I  AV +
Sbjct: 280 TPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNHADQIQNAVLS 339

Query: 343 NLREGAIT-TPDLGGKASTQQVVDDVLSRL 371
            +  G    T DL G A+T    + V+ RL
Sbjct: 340 TIASGPENRTGDLAGTATTSSFTEAVIKRL 369

>CAGL0I07227g Chr9 complement(696605..697711) [1107 bp, 368 aa] {ON}
           highly similar to uniprot|P28241 Saccharomyces
           cerevisiae YOR136w IDH2 isocitrate dehydrogenase
          Length = 368

 Score =  175 bits (443), Expect = 1e-50,   Method: Compositional matrix adjust.
 Identities = 133/382 (34%), Positives = 192/382 (50%), Gaps = 39/382 (10%)

Query: 8   RVSACRGLAT------------NAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGL 55
           R++A R LAT            N +    T+  I GDGIG E+  + K++ +  +    +
Sbjct: 8   RLNARRFLATAQPSIGRFTGKPNPSTGKFTVSFIEGDGIGPEISSSVKRIFQAADVP--V 65

Query: 56  SFNFIDLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRR 115
            +   D+   F     T   +PD  V  + K    AL G + +P  K  G+ S  + LR+
Sbjct: 66  EWETCDVTPIFVNGLTT---IPDPAVQSINKNLV-ALKGPLATPIGK--GHRSLNLTLRK 119

Query: 116 EMGLFANVRPVKSVEGSRN--KPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRI 173
              LFANVRP KS+EG +   + +D+V++RENTE  Y  IE           V  + K I
Sbjct: 120 TFNLFANVRPAKSIEGFKTTYENVDLVLIRENTEGEYSGIEHL-----VSPGVVQSIKLI 174

Query: 174 SEIATRRIATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYG 233
           +  A+ R+   A + A    +  G   L V HKS +    DGLF  + KE+      +Y 
Sbjct: 175 TRDASERVIRYAYEYA----RAIGRPRLIVVHKSTIQRLADGLFVNVAKEL----AAEYP 226

Query: 234 QIKYNEQIVDSMVYRLFREPQCFD--VIVAPNLYGDILSDGAAAL-VGSLGVVPSANVGP 290
            I+   +++D+    +   P  +   V V PNLYGDILSD  + L  GSLG+ PSAN+G 
Sbjct: 227 DIQLETELIDNTCLNVVSNPSSYTDAVSVCPNLYGDILSDLNSGLSAGSLGLTPSANIGH 286

Query: 291 EIVIGEPCHGSAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGA-I 349
           ++ I E  HGSAPDIAG+  ANP A + S+ +ML  +G    A  I KAV   +  G+  
Sbjct: 287 KVSIFEAVHGSAPDIAGQNKANPTALLLSSVMMLNHMGMTEHADRIEKAVLGTIAGGSEY 346

Query: 350 TTPDLGGKASTQQVVDDVLSRL 371
            T DLGG AST    D ++ +L
Sbjct: 347 RTGDLGGSASTTSFTDAIIKKL 368

>TDEL0C03840 Chr3 complement(673007..674092) [1086 bp, 361 aa] {ON}
           Anc_2.278 YNL037C
          Length = 361

 Score =  174 bits (442), Expect = 1e-50,   Method: Compositional matrix adjust.
 Identities = 133/374 (35%), Positives = 188/374 (50%), Gaps = 28/374 (7%)

Query: 1   MFRSVATRVSACRGLATNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFI 60
           MF SVA    A   +          + LIPGDG+GKEV  +   + E  N    + ++ +
Sbjct: 10  MFASVA----AAEKVLPKKYGGRFVVTLIPGDGVGKEVTDSVVSIFEAENLP--IDWDRV 63

Query: 61  DLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLF 120
           D+ +G     E G       V+ LK+   G L G   +      G  S  VALR+E+ ++
Sbjct: 64  DI-SGLD--HEEG---VQAAVDSLKRNKIG-LKGIWHTSAADQAGKGSLNVALRKELDIY 116

Query: 121 ANVRPVKSVEGSRNK--PIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIAT 178
           ANV   KSV G + K   +D+V++RENTE  Y  +E   +       V ++ K ++E  T
Sbjct: 117 ANVALFKSVPGVKTKIPNVDLVVIRENTEGEYSGLEHESVPG-----VVESLKIMTEDKT 171

Query: 179 RRIATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYN 238
            RIA  A D A K         +T  HK+N++   DGLFR +   V E    +Y  +K  
Sbjct: 172 ERIARFAFDFAKKY----NRHAVTAVHKANIMKLGDGLFRNVVTRVGEQ---EYPDVKVG 224

Query: 239 EQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEP- 297
             IVD+   +   +P  FDV+V P++YG IL +  AAL+G  G+V  AN G E  + EP 
Sbjct: 225 SIIVDNASMQTVAKPHQFDVLVTPSMYGTILGNIGAALIGGPGLVAGANYGREYAVFEPG 284

Query: 298 CHGSAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGK 357
                 DI  K IANP A I S +LML+ LG + +A  I  AV   + EG  TTPD+GG 
Sbjct: 285 SRHVGLDIKDKNIANPTAMILSASLMLDHLGLSTSATKISNAVHQVIAEGKSTTPDIGGS 344

Query: 358 ASTQQVVDDVLSRL 371
           AST +    V+ +L
Sbjct: 345 ASTTEFTQAVIEKL 358

>Kpol_543.8 s543 (21411..22517) [1107 bp, 368 aa] {ON}
           (21411..22517) [1107 nt, 369 aa]
          Length = 368

 Score =  174 bits (441), Expect = 2e-50,   Method: Compositional matrix adjust.
 Identities = 125/360 (34%), Positives = 188/360 (52%), Gaps = 27/360 (7%)

Query: 18  NAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFIDLYAGFQTFQETGKALP 77
           + A    T+  I GDG+G E+  + K++     +K  + +   D+   F   Q T   +P
Sbjct: 30  DPATGKFTVPFIEGDGVGPEISESVKKIFSA--AKVPIEWVPCDVGPIFVNGQTT---IP 84

Query: 78  DETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLFANVRPVKSVEGSRN--K 135
           +  V ++ K    AL G + +P  K  G+ S  + LR+   LFANVRP +S+   ++  +
Sbjct: 85  EPAVELINKHLI-ALKGPLATPIGK--GHRSLNLTLRKTFNLFANVRPARSIPNYKSTYE 141

Query: 136 PIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALKRLQT 195
            +D+V++RENTE  Y  IE           V  + K I+  AT R+   A +      Q 
Sbjct: 142 NVDLVLIRENTEGEYSGIEHVITPG-----VIQSIKLITREATERVVRYAFEYT----QA 192

Query: 196 RGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFREPQC 255
            G   L V HKS +    DGLF ++ +E+      +Y  IK   +I+D  +  +  +P+ 
Sbjct: 193 IGRPRLLVIHKSTIQRMADGLFVKVAEEL----ASEYPDIKLETEIIDKSILNVVSKPEL 248

Query: 256 FD--VIVAPNLYGDILSDGAAAL-VGSLGVVPSANVGPEIVIGEPCHGSAPDIAGKGIAN 312
           +   V V PNLYGDILSD  + L  GSLG+ PSAN+G ++ I E  HGSAPDIAG+  AN
Sbjct: 249 YSDAVSVCPNLYGDILSDLNSGLSAGSLGLTPSANIGDKVSIFEAVHGSAPDIAGQNKAN 308

Query: 313 PIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAIT-TPDLGGKASTQQVVDDVLSRL 371
           P A + S+ +ML+ +G +  A  I  AV   +  G+   T DL G AST    ++V+ RL
Sbjct: 309 PTALLLSSVMMLKHMGLDEHANKIENAVLTTIASGSENRTADLSGTASTSSFTEEVIQRL 368

>Skud_15.300 Chr15 (534346..535455) [1110 bp, 369 aa] {ON} YOR136W
           (REAL)
          Length = 369

 Score =  174 bits (440), Expect = 3e-50,   Method: Compositional matrix adjust.
 Identities = 136/390 (34%), Positives = 193/390 (49%), Gaps = 40/390 (10%)

Query: 1   MFRSVATRVSACRGLAT-------------NAARKSLTIGLIPGDGIGKEVIPAGKQVLE 47
           M RS   R ++ R LAT             N +    T+  I GDGIG E+  + K++  
Sbjct: 1   MLRSNLFRNTSRRFLATVKQPSIGRFTGKPNPSTGRYTVSFIEGDGIGPEISKSVKKIFN 60

Query: 48  NLNSKHGLSFNFIDLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYS 107
             N    + +   D+   F     T   +PD  V  +      AL G + +P  K  G+ 
Sbjct: 61  AANVP--IEWESCDVNPIFVNGLTT---IPDAAVQSITNNLI-ALKGPLATPIGK--GHR 112

Query: 108 SPIVALRREMGLFANVRPVKSVEGSRN--KPIDMVIVRENTEDLYIKIEKTYIDKATGTR 165
           S  + LR+  GLFANVRP KSVEG +   + +D+V++RENTE  Y  IE           
Sbjct: 113 SLNLTLRKTFGLFANVRPAKSVEGFKTTYENVDLVLIRENTEGEYSGIEHIVCPG----- 167

Query: 166 VADATKRISEIATRRIATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVY 225
           V  + K I+  A+ R+   A + A    +  G   + V HKS +    DGLF  + KE+ 
Sbjct: 168 VVQSIKLITRDASERVIRYAFEYA----RAIGRPRVIVVHKSTIQRLADGLFVNVAKELS 223

Query: 226 ESNKDKYGQIKYNEQIVDSMVYRLFREPQCFD--VIVAPNLYGDILSDGAAAL-VGSLGV 282
           +    +Y  I    +++D+ V ++   P  +   V V PNLYGDILSD  + L  GSLG+
Sbjct: 224 K----EYPDIILETELIDNSVLKVVTNPSAYTNAVSVCPNLYGDILSDLNSGLSAGSLGL 279

Query: 283 VPSANVGPEIVIGEPCHGSAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDA 342
            PSAN+G +I I E  HGSAPDIAG+  ANP A + S+ +ML  +G    A  I  AV +
Sbjct: 280 TPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNHADQIQNAVLS 339

Query: 343 NLREGAIT-TPDLGGKASTQQVVDDVLSRL 371
            +  G    T DL G A+T    + V+ RL
Sbjct: 340 TIASGPENRTGDLAGTATTSSFTEAVIKRL 369

>Ecym_2313 Chr2 complement(610493..611605) [1113 bp, 370 aa] {ON}
           similar to Ashbya gossypii AFR137C
          Length = 370

 Score =  174 bits (440), Expect = 3e-50,   Method: Compositional matrix adjust.
 Identities = 126/353 (35%), Positives = 183/353 (51%), Gaps = 27/353 (7%)

Query: 25  TIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFIDLYAGFQTFQETGKALPDETVNVL 84
           T+  I GDGIG E+  + K +     +K  + + + D+   F     T   +PD  V  +
Sbjct: 39  TVSFIEGDGIGPEISQSVKDIFSA--AKVPVEWEYCDVTPIFINGLTT---IPDPAVQSI 93

Query: 85  KKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLFANVRPVKSVEGSRN--KPIDMVIV 142
            K    AL G + +P  K  G+ S  + LR+  GLFANVRP KS+EG +   + +D+V++
Sbjct: 94  NKNLV-ALKGPLATPIGK--GHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYENVDLVLI 150

Query: 143 RENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALKRLQTRGEATLT 202
           RENTE  Y  IE           V  + K I+  A+ R+   A + A    +  G   + 
Sbjct: 151 RENTEGEYSGIEHV-----VSPGVVQSIKLITRDASERVIRYAFEYA----RAVGRPKVV 201

Query: 203 VTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFREPQCFD--VIV 260
           V HKS +    DGLF  + +EV      +Y  I+   +++D+ V  +  +P+ +   V V
Sbjct: 202 VVHKSTIQRLADGLFVNVAQEV----GKEYPDIELQPELIDNTVLNVVSKPEKYSDSVAV 257

Query: 261 APNLYGDILSDGAAAL-VGSLGVVPSANVGPEIVIGEPCHGSAPDIAGKGIANPIATIRS 319
            PNLYGDILSD  + L  GSLG+ PSAN+G  + I E  HGSAPDIAG+  ANP A + S
Sbjct: 258 CPNLYGDILSDLNSGLSAGSLGLTPSANIGHTVSIFEAVHGSAPDIAGQNCANPTALLLS 317

Query: 320 TALMLEFLGHNGAAQDIYKAVDANL-REGAITTPDLGGKASTQQVVDDVLSRL 371
           + +ML  +G +  A  I  AV A +  +    T DL G A+T      V+ RL
Sbjct: 318 SVMMLNHMGLHEHADQIESAVLATVASDKKNRTADLAGTATTSSFTKAVIERL 370

>AFR137C Chr6 complement(685586..686689) [1104 bp, 367 aa] {ON}
           Syntenic homolog of Saccharomyces cerevisiae YOR136W
           (IDH2)
          Length = 367

 Score =  174 bits (440), Expect = 3e-50,   Method: Compositional matrix adjust.
 Identities = 131/366 (35%), Positives = 191/366 (52%), Gaps = 40/366 (10%)

Query: 18  NAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFID----LYAGFQTFQETG 73
           NAA K  T+  I GDG+G E+  + K +    +    + + + D    L  G  T     
Sbjct: 30  NAAGK-YTVSFIEGDGVGPEISQSVKDIFSAASVP--VEWEYCDVTPLLVNGLTT----- 81

Query: 74  KALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLFANVRPVKSVEGSR 133
             +P+  V  + K    AL G + +P  K  G+ S  + LR+  GLFANVRP KS+EG +
Sbjct: 82  --IPEPAVASINKNLV-ALKGPLATPIGK--GHRSLNLTLRKTFGLFANVRPAKSIEGYK 136

Query: 134 N--KPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALK 191
                +D+V++RENTE  Y  IE           V  + K I+  A+ R+   A + A  
Sbjct: 137 TTYSDVDLVLIRENTEGEYSGIEHV-----VSPGVVQSIKLITREASERVIRYAFEYA-- 189

Query: 192 RLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFR 251
             +T G   + V HKS +    DGLF  + +E+      +Y  I+   +++D+ V  +  
Sbjct: 190 --RTVGRPKVVVVHKSTIQRLADGLFVNVAQEL----GREYPDIELQTELLDNTVLNVVT 243

Query: 252 EPQCFDVIVA--PNLYGDILSDGAAAL-VGSLGVVPSANVGPEIVIGEPCHGSAPDIAGK 308
           +P+ +  +VA  PNLYGDILSD  + L  GSLG+ PSAN+G ++ I E  HGSAPDIAG+
Sbjct: 244 KPEAYKDVVAVCPNLYGDILSDLNSGLSAGSLGLTPSANIGHQVSIFEAVHGSAPDIAGQ 303

Query: 309 GIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANL---REGAITTPDLGGKASTQQVVD 365
             ANP A + S+ +ML  +G +  A  I KAV + +   RE    T DL G AST    +
Sbjct: 304 NRANPTALLLSSVMMLNHMGLHEHAGRIEKAVLSTIASSREN--RTADLAGTASTSSFTN 361

Query: 366 DVLSRL 371
            V+ RL
Sbjct: 362 AVIERL 367

>SAKL0G03520g Chr7 (290768..291877) [1110 bp, 369 aa] {ON} highly
           similar to uniprot|P28241 Saccharomyces cerevisiae
           YOR136W IDH2 Subunit of mitochondrial NAD( )- dependent
           isocitrate dehydrogenase which catalyzes the oxidation
           of isocitrate to alpha-ketoglutarate in the TCA cycle
          Length = 369

 Score =  173 bits (439), Expect = 4e-50,   Method: Compositional matrix adjust.
 Identities = 128/360 (35%), Positives = 185/360 (51%), Gaps = 27/360 (7%)

Query: 18  NAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFIDLYAGFQTFQETGKALP 77
           N +    T+  I GDG+G E+  + K +     ++  + +   D+   F     T   +P
Sbjct: 31  NPSTGKYTVSFIEGDGVGPEISKSVKDIFAA--AEVPVEWESCDVTPLFINGLTT---IP 85

Query: 78  DETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLFANVRPVKSVEGSRN--K 135
              V+ + K    AL G + +P  K  G+ S  + LR+  GLFANVRP KSVEG +   +
Sbjct: 86  QPAVDSINKNLI-ALKGPLATPIGK--GHRSLNLTLRKTFGLFANVRPAKSVEGFKTTYE 142

Query: 136 PIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALKRLQT 195
            +D+V++RENTE  Y  IE           V  + K I+  A+ R+   A + A    + 
Sbjct: 143 NVDLVLIRENTEGEYSGIEHV-----VSPGVVQSIKLITRDASERVIRYAFEYA----RA 193

Query: 196 RGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFREPQC 255
            G   + V HKS +    DGLF ++ KE+      +Y  I+   Q++D+ V  +   P  
Sbjct: 194 VGRPKVMVVHKSTIQRLADGLFVDVAKEL----SSEYPDIQLQLQLLDNTVLNVVSNPGA 249

Query: 256 F--DVIVAPNLYGDILSDGAAAL-VGSLGVVPSANVGPEIVIGEPCHGSAPDIAGKGIAN 312
           +   V V PNLYGDILSD  + L  GSLG+ PSAN+G ++ I E  HGSAPDIAG+  AN
Sbjct: 250 YADTVSVCPNLYGDILSDLNSGLSAGSLGLTPSANIGHKVSIFEAVHGSAPDIAGQNKAN 309

Query: 313 PIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAIT-TPDLGGKASTQQVVDDVLSRL 371
           P A + S+ +ML  +G    A  I KAV + +  G    T DL G AST    + V+ RL
Sbjct: 310 PTALLLSSVMMLNHMGLYEKADSIEKAVLSTIASGPENRTADLAGSASTSSFTEAVIKRL 369

>TBLA0B06910 Chr2 (1634845..1635942) [1098 bp, 365 aa] {ON} 
          Length = 365

 Score =  172 bits (437), Expect = 8e-50,   Method: Compositional matrix adjust.
 Identities = 135/390 (34%), Positives = 203/390 (52%), Gaps = 47/390 (12%)

Query: 1   MFRSVATRVSACRGLATNAA---RKSL-----------TIGLIPGDGIGKEVIPAGKQVL 46
           MF++V     A RGLAT  A   R  L           T+ LIPGDG+GKEV  +   + 
Sbjct: 1   MFKTVL----AKRGLATVPATGFRGFLNPLPKEYGGRYTVTLIPGDGVGKEVTDSVVSIF 56

Query: 47  --ENLNSKHGLSFNFIDLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVE 104
             ENL     + +  +D+ +G     E G    +  VN LK+   G     +   +    
Sbjct: 57  NAENLP----IDWERVDI-SGLD--HEEGV---EAAVNSLKRNKIG--LKGIWHTSAGQS 104

Query: 105 GYSSPIVALRREMGLFANVRPVKSVEG--SRNKPIDMVIVRENTEDLYIKIEKTYIDKAT 162
            + S  VALR+++ ++ANV   K++ G  +R   +D+VI+RENTE  Y  +E   +    
Sbjct: 105 DHGSLNVALRKQLDIYANVAHFKTLPGVKTRIPDVDLVIIRENTEGEYSGLEHESVPG-- 162

Query: 163 GTRVADATKRISEIATRRIATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICK 222
              V ++ K I++  + RIA  A D A KR   +    +T  HK+N++   DGLFR    
Sbjct: 163 ---VVESLKIITKEKSERIARFAFDFA-KRFDRK---LVTAVHKANIMKLGDGLFRNSVT 215

Query: 223 EVYESNKDKYGQIKYNEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGV 282
            + E+   +Y  IK +  IVD+   +   +P  FDV+V P++YG IL +  AAL+G  G+
Sbjct: 216 SIGET---EYPDIKVSSIIVDNASMQSVAKPHQFDVLVTPSMYGTILGNIGAALIGGPGL 272

Query: 283 VPSANVGPEIVIGEP-CHGSAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVD 341
           VP AN G E  + EP       DI G+ +ANP A I S+ L+L+ LG N  A+ I  AV 
Sbjct: 273 VPGANYGTECAVFEPGSRHVGLDIKGQNVANPTAMILSSTLLLKHLGLNNEAKKIEDAVY 332

Query: 342 ANLREGAITTPDLGGKASTQQVVDDVLSRL 371
             + EG +TT D+GG AST +  ++++ +L
Sbjct: 333 KTIAEGKVTTRDIGGSASTTEFTNEIIKKL 362

>Kpol_1039.35 s1039 complement(108102..109181) [1080 bp, 359 aa]
           {ON} complement(108102..109181) [1080 nt, 360 aa]
          Length = 359

 Score =  172 bits (436), Expect = 8e-50,   Method: Compositional matrix adjust.
 Identities = 124/385 (32%), Positives = 197/385 (51%), Gaps = 43/385 (11%)

Query: 1   MFRSVATRVSACRGLATNAARKSL---------TIGLIPGDGIGKEVIPAGKQVLENLNS 51
           MFR++ ++    R   + A+R+++         T+ L+PGDG+G+E+  +   + E  N 
Sbjct: 1   MFRNLISK----RAFTSIASRENIIPKKYGGRYTVTLLPGDGVGREITDSVVSIFEAEN- 55

Query: 52  KHGLSFNFIDLYAGFQTFQETGKALPD--ETVNVLKKQCQGALFGAVQSPTTKVEGYSSP 109
                     L   ++  + +G    D    V  LK+   G     +   +   +G++S 
Sbjct: 56  ----------LPIDWERVELSGLEQEDVHTAVESLKRNKIG--LKGIWHTSADHDGHTSW 103

Query: 110 IVALRREMGLFANVRPVKSVEG--SRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVA 167
            VALR+E+ ++ANV   KS +G  +R   +D+VI+RENTE  Y  +E   +       V 
Sbjct: 104 NVALRKELDIYANVAIFKSFKGVDTRIPDVDLVIIRENTEGEYSGLEHESVPG-----VV 158

Query: 168 DATKRISEIATRRIATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYES 227
           ++ K ++   T RIA  A D A+K        ++T  HK+N++   DGLFR +  E+   
Sbjct: 159 ESLKIMTAQKTERIARFAFDYAMKY----NRKSVTAVHKANIMKLGDGLFRNLVTEI--- 211

Query: 228 NKDKYGQIKYNEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSAN 287
              +Y ++  +  IVD+   +   +P  FDV+VAP++YG IL +  AAL+G  G+VP AN
Sbjct: 212 GAKEYPEVGVSSIIVDNASMQAVAKPHQFDVMVAPSMYGTILGNIGAALIGGPGLVPGAN 271

Query: 288 VGPEIVIGEP-CHGSAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLRE 346
            G +  + EP       DI  + IANP A I S  LML  LG    A  I KAV   + E
Sbjct: 272 YGRDYAVFEPGSRHVGLDIENQNIANPTAMILSATLMLNHLGFRNDAARISKAVHEVIAE 331

Query: 347 GAITTPDLGGKASTQQVVDDVLSRL 371
           G  TT D+GG A+T +  + V+++L
Sbjct: 332 GKTTTRDIGGSATTTEFTNAVIAKL 356

>Kwal_55.21273 s55 complement(762121..763227) [1107 bp, 368 aa] {ON}
           YOR136W (IDH2) - NAD+-dependent isocitrate dehydrogenase
           [contig 130] FULL
          Length = 368

 Score =  172 bits (437), Expect = 8e-50,   Method: Compositional matrix adjust.
 Identities = 129/353 (36%), Positives = 188/353 (53%), Gaps = 27/353 (7%)

Query: 25  TIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFIDLYAGFQTFQETGKALPDETVNVL 84
           T+  I GDG+G E+  A K +     +K  + +   D+   F     T   +P    + +
Sbjct: 37  TVSFIEGDGVGPEISKAVKDIFAA--AKAPIQWETCDVTPLFINGLTT---IPQPAQDSI 91

Query: 85  KKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLFANVRPVKSVEGSRN--KPIDMVIV 142
            K    AL G + +P  K  G+ S  + LR+  GLFANVRP KS++G +     +D+V++
Sbjct: 92  NKNLI-ALKGPLATPIGK--GHRSLNLTLRKTFGLFANVRPAKSIQGFKTAYDNVDLVLI 148

Query: 143 RENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALKRLQTRGEATLT 202
           RENTE  Y  IE      A G  V  + K I++ A+ R+   A + A  R   R +  + 
Sbjct: 149 RENTEGEYSGIEHVV---APG--VVQSIKLITQDASERVIRYAFEYA--RAVERPK--VL 199

Query: 203 VTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFREPQCFD--VIV 260
           V HKS +    DGLF  + +++ +    +Y  I+   +++D+ V    R+P  +   V+V
Sbjct: 200 VVHKSTIQRLADGLFVSVAEKLAK----EYPDIELQTELIDNTVLHTVRDPLKYSDVVVV 255

Query: 261 APNLYGDILSDGAAAL-VGSLGVVPSANVGPEIVIGEPCHGSAPDIAGKGIANPIATIRS 319
            PNLYGDILSD  + L  GSLG+ PSAN+G E+ I E  HGSAPDIAG+  ANP A + S
Sbjct: 256 CPNLYGDILSDMNSGLSAGSLGLTPSANIGHEVSIFEAVHGSAPDIAGQNKANPTALLLS 315

Query: 320 TALMLEFLGHNGAAQDIYKAVDANLREGAIT-TPDLGGKASTQQVVDDVLSRL 371
           + +ML  +G    A  I KAV + +  G    T DL G AST    + V+SRL
Sbjct: 316 SVMMLNHMGLTEHADKIEKAVFSTIASGPENRTGDLAGSASTSSFAEAVISRL 368

>NDAI0B03590 Chr2 complement(901108..902187) [1080 bp, 359 aa] {ON}
           Anc_2.278
          Length = 359

 Score =  169 bits (429), Expect = 8e-49,   Method: Compositional matrix adjust.
 Identities = 117/351 (33%), Positives = 190/351 (54%), Gaps = 25/351 (7%)

Query: 24  LTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFIDLYAGFQTFQETGKALPDETVNV 83
            T+ L+PGDG+GKE+  +   + ++ N    + +  +D+     T  E  KA     V+ 
Sbjct: 28  FTVTLLPGDGVGKEITDSVVSIFKSENVP--IDWETVDISGLDHT--EGVKA----AVDS 79

Query: 84  LKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLFANVRPVKSVEGSRNK--PIDMVI 141
           LK+   G L G   +P  +V G+ S  VA R+++ ++ANV   KS+EG + K   +D+V+
Sbjct: 80  LKRNKIG-LKGIWHTPADQV-GHGSLNVAFRKQLDIYANVAIFKSIEGVKTKIPNVDLVV 137

Query: 142 VRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALKRLQTRGEATL 201
           +RENTE  Y  +E   +       V ++ K I++  + RIA  A D A    +     ++
Sbjct: 138 IRENTEGEYSGLEHESVPG-----VVESLKIITKSKSERIARFAFDFA----KRNNRKSV 188

Query: 202 TVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFREPQCFDVIVA 261
           T  HK+N++  +DGLFR    ++ E   ++Y +I+ +  IVD+   +   +P  FDV+V 
Sbjct: 189 TAVHKANIMKLSDGLFRNTVSKIGE---EEYPEIQTSSIIVDNASMQAVAKPHQFDVMVT 245

Query: 262 PNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEP-CHGSAPDIAGKGIANPIATIRST 320
           P++YG I+ +  AAL+G  G+VP  N G +  + EP       DI G+ +ANP A + S 
Sbjct: 246 PSMYGTIVGNIGAALIGGPGLVPGVNYGRDYAVFEPGSRHVGLDIKGQNVANPTAMLLSA 305

Query: 321 ALMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKASTQQVVDDVLSRL 371
            L+L+ LG   +A  I  AV   + EG  TT D+GG AST +    V+++L
Sbjct: 306 TLLLDHLGLEKSANRIKSAVYDVIAEGKATTQDIGGSASTTEFTQAVINKL 356

>ZYRO0D02838g Chr4 (223132..224217) [1086 bp, 361 aa] {ON} similar
           to uniprot|P28834 Saccharomyces cerevisiae YNL037C IDH1
           Subunit of mitochondrial NAD( )-dependent isocitrate
           dehydrogenase which catalyzes the oxidation of
           isocitrate to alpha-ketoglutarate in the TCA cycle
          Length = 361

 Score =  169 bits (429), Expect = 1e-48,   Method: Compositional matrix adjust.
 Identities = 127/383 (33%), Positives = 200/383 (52%), Gaps = 37/383 (9%)

Query: 1   MFRSVATRVSACRGLATNAARKSL---------TIGLIPGDGIGKEVIPAGKQVLENLNS 51
           MFR   T+    R LAT A  + +         T+ LIPGDG+GKEV  +   + +  N 
Sbjct: 1   MFRHSLTK----RTLATVATTEKMLPKKYGGRYTVTLIPGDGVGKEVTDSVVSIFKAENV 56

Query: 52  KHGLSFNFIDLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIV 111
              + ++ +D+ +G    ++   A     V  LK+   G L G   +      G+ S  V
Sbjct: 57  P--VDWDRVDI-SGVDRAEDVKSA-----VESLKRNRIG-LKGIWHTSPADQAGHGSLNV 107

Query: 112 ALRREMGLFANVRPVKSVEGSRNK--PIDMVIVRENTEDLYIKIEKTYIDKATGTRVADA 169
           ALR+E+ ++ANV   KS+ G + K   +D+V++RENTE  +  +E   +       V ++
Sbjct: 108 ALRKELDIYANVARFKSIPGVQVKIPDVDLVVIRENTEGEFSGLEHESVPG-----VVES 162

Query: 170 TKRISEIATRRIATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNK 229
            K +++    RIA  A D A K  + +    +   HK+N++   DGLF+ + +EV E   
Sbjct: 163 LKIMTQDNIERIARFAFDYAKKNDRKQ----VVAVHKANIMKMGDGLFKNLVQEVGEK-- 216

Query: 230 DKYGQIKYNEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVG 289
            +Y +++    IVD+   +    P  FDV+V P++YG IL +  AAL+G  G+V  AN G
Sbjct: 217 -EYPELQVGNIIVDNASMQTVANPHQFDVLVTPSMYGTILGNIGAALIGGPGLVAGANYG 275

Query: 290 PEIVIGEP-CHGSAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGA 348
            ++ + EP       DI G+ +ANP A I S+ L+L  LG N +A  I KAV A + EG 
Sbjct: 276 RDVALFEPGSRHVGLDIKGQNVANPTAMILSSVLLLNHLGLNTSADRISKAVHAVIAEGK 335

Query: 349 ITTPDLGGKASTQQVVDDVLSRL 371
             T D+GG AST +  + V+++L
Sbjct: 336 SVTRDIGGTASTTEFTEAVINKL 358

>CAGL0G02673g Chr7 complement(246455..247531) [1077 bp, 358 aa] {ON}
           highly similar to uniprot|P28834 Saccharomyces
           cerevisiae YNL037c IDH1 or uniprot|P28241 Saccharomyces
           cerevisiae YOR136w IDH2
          Length = 358

 Score =  169 bits (427), Expect = 2e-48,   Method: Compositional matrix adjust.
 Identities = 124/382 (32%), Positives = 194/382 (50%), Gaps = 38/382 (9%)

Query: 1   MFRSVATRVSACRGLATNAARKSL--------TIGLIPGDGIGKEVIPAGKQVLENLNSK 52
           MFR+V  R     G+A+ A    L        T+ LIPGDG+GKE+  +   + E  N  
Sbjct: 1   MFRTVQRR-----GMASMAKELVLPKKYGGRYTVTLIPGDGVGKEITDSVVSIFEAENIP 55

Query: 53  HGLSFNFIDLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVA 112
             + +  +D+       Q+  +A     V  LK+   G     +   +  +  + S  VA
Sbjct: 56  --VDWERVDISTS-DNIQDVSQA-----VESLKRNKIG--LKGIWHTSADIADHGSFNVA 105

Query: 113 LRREMGLFANVRPVKSVEGSRNK--PIDMVIVRENTEDLYIKIEKTYIDKATGTRVADAT 170
           LR+++ +FA+V   KSV G + K   +D+V++RENTE  Y  +E   +       V ++ 
Sbjct: 106 LRKQLDMFAHVAFFKSVPGVKTKIPNVDLVVIRENTEGEYSGLEHESVPG-----VVESL 160

Query: 171 KRISEIATRRIATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKD 230
           K I++  + RIA  A D A K        ++   HK+N++   DGLFR    E+     +
Sbjct: 161 KIITKAKSERIARFAFDFAKKY----NRKSVCAVHKANIMKMGDGLFRNTVTEI---GAN 213

Query: 231 KYGQIKYNEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGP 290
           +Y  I+ +  IVD+   +   +P  FDV+V P++YG I+ +  AAL+G  G+V  A+ G 
Sbjct: 214 EYPDIQTSSIIVDNASMQAVAKPHQFDVMVTPSMYGTIIGNIGAALIGGPGLVAGAHYGR 273

Query: 291 EIVIGEP-CHGSAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAI 349
           E  + EP       DI GK +ANP A I S+ LML+ LG   +A+ I KA    +  G +
Sbjct: 274 EHAVFEPGSQHVGLDIKGKNVANPTAMILSSTLMLQHLGLTESAKRIAKATHDVISLGQV 333

Query: 350 TTPDLGGKASTQQVVDDVLSRL 371
           TT D+GG AST +  + ++ RL
Sbjct: 334 TTKDIGGSASTTEFTEAIIKRL 355

>TPHA0J02770 Chr10 (617727..618857) [1131 bp, 376 aa] {ON} Anc_2.278
           YNL037C
          Length = 376

 Score =  169 bits (427), Expect = 2e-48,   Method: Compositional matrix adjust.
 Identities = 128/375 (34%), Positives = 191/375 (50%), Gaps = 27/375 (7%)

Query: 3   RSVATRVSACRGLATNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFIDL 62
           RS++ + +  R      +  + T+  I GDG+G E+  + K +    N    + +   D+
Sbjct: 23  RSISNQPTIGRFTGKTNSSGTYTVPFIEGDGVGPEISKSVKDIFSAANVP--IQWQPCDV 80

Query: 63  YAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLFAN 122
              F     T   +P+  V  +K+    AL G + +P  K  G+ S  + LR+   LFAN
Sbjct: 81  GPIFVNGLTT---IPEPAVKAIKESLV-ALKGPLATPVGK--GHRSLNLTLRKTFDLFAN 134

Query: 123 VRPVKSVEGSRN--KPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRR 180
           VRP KSV   ++  + +D+V++RENTE  Y  IE           V  + K I+  A+ +
Sbjct: 135 VRPAKSVPNYKSTYENVDLVLIRENTEGEYSGIEHIVTPG-----VVQSIKLITREASEK 189

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQ 240
           +   A + A+      G   L V HKS +    DGLF +I  E+    + +Y  IK   Q
Sbjct: 190 VIRYAYEYAI----AVGRPRLIVVHKSTIQRLGDGLFVQIANEL----QSEYPSIKLETQ 241

Query: 241 IVDSMVYRLFREPQCFD--VIVAPNLYGDILSDGAAAL-VGSLGVVPSANVGPEIVIGEP 297
           I+D+ V  +   P  +   V V PNLYGDILSD  + L  GSLG+ PSAN+G ++ I E 
Sbjct: 242 ILDNTVLNVVSNPTLYKDAVSVCPNLYGDILSDLNSGLSAGSLGLTPSANIGDKVSIFEA 301

Query: 298 CHGSAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAIT-TPDLGG 356
            HGSAPDIAG+  ANP A + S+ +ML  +G    A  I  AV + +  G  + T DLGG
Sbjct: 302 VHGSAPDIAGQNKANPTALLLSSVMMLNHMGLEEHASRIENAVLSTIASGPESRTGDLGG 361

Query: 357 KASTQQVVDDVLSRL 371
            A+T    + V+ +L
Sbjct: 362 SATTSSFTECVIKKL 376

>KAFR0B06370 Chr2 complement(1317952..1319088) [1137 bp, 378 aa]
           {ON} Anc_5.473 YOR136W
          Length = 378

 Score =  169 bits (427), Expect = 3e-48,   Method: Compositional matrix adjust.
 Identities = 125/357 (35%), Positives = 182/357 (50%), Gaps = 33/357 (9%)

Query: 25  TIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFID----LYAGFQTFQETGKALPDET 80
           T+  I GDGIG E+  + K + +  +    +++   D    L  G  T       +PDE 
Sbjct: 45  TVSFIEGDGIGPEISRSVKDIFQAASVP--ITWETCDVSPILVDGLTT-------IPDEA 95

Query: 81  VNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLFANVRPVKSVEGSRN--KPID 138
           V  + K   G L G + +P  K  G+ S  + LR+   LFANVRP KSV G +     +D
Sbjct: 96  VKSINKNLVG-LKGPLATPIGK--GHRSLNLTLRKTFNLFANVRPAKSVRGFKTTYDNVD 152

Query: 139 MVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALKRLQTRGE 198
           +V++RENTE  Y  IE           V  + K I+  A+ R+   A + A    +  G 
Sbjct: 153 LVLIRENTEGEYSGIEHVVTPG-----VVQSIKLITRDASERVIRYAFEYA----KAIGR 203

Query: 199 ATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFREPQCFD- 257
             + V HKS +   +DGLF  + KE+ +  +  +  I+ + +++D+ V  +   P  +  
Sbjct: 204 PKVIVVHKSTIQRLSDGLFVNVAKELQK--EKNFQNIELDTELIDNTVLNVVMNPSKYSD 261

Query: 258 -VIVAPNLYGDILSDGAAAL-VGSLGVVPSANVGPEIVIGEPCHGSAPDIAGKGIANPIA 315
            V V PNLYGDILSD  + L  GSLG+ PSAN+G +I I E  HGSAPDIAG+  ANP A
Sbjct: 262 AVFVCPNLYGDILSDLNSGLSAGSLGLTPSANIGDKISIFEAVHGSAPDIAGQNKANPTA 321

Query: 316 TIRSTALMLEFLGHNGAAQDIYKAVDANLREGAIT-TPDLGGKASTQQVVDDVLSRL 371
            + S+ +ML  +G N     I  AV   +   +   T DLGG A+T    + V+  L
Sbjct: 322 LLLSSVMMLHHMGLNEYGDKIENAVLKTIAASSKNRTGDLGGTATTTSFTEAVIDNL 378

>TDEL0A03370 Chr1 (599855..600970) [1116 bp, 371 aa] {ON} Anc_5.473
           YOR136W
          Length = 371

 Score =  167 bits (424), Expect = 6e-48,   Method: Compositional matrix adjust.
 Identities = 127/357 (35%), Positives = 183/357 (51%), Gaps = 35/357 (9%)

Query: 25  TIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFID----LYAGFQTFQETGKALPDET 80
           T+  I GDG+G E+  + K +     +K  + +        L  G  T  E  +    E+
Sbjct: 40  TVSFIEGDGVGPEISKSVKDIFA--AAKVPIVWESCPVTPLLVNGVTTIPEQAQ----ES 93

Query: 81  VNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLFANVRPVKSVEGSRN--KPID 138
           +N    +   AL G + +P  K  G+ S  + LR+  GLFANVRP KSVEG +   + +D
Sbjct: 94  IN----RNLVALKGPLATPIGK--GHRSMNLTLRKTFGLFANVRPAKSVEGFKTTYEDVD 147

Query: 139 MVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALKRLQTRGE 198
           +V++RENTE  Y  IE   +       V  + K I+  A+ R+   A + A    +  G 
Sbjct: 148 LVLIRENTEGEYAGIEHVIVPG-----VVQSIKLITREASERVIRYAYEYA----RAVGR 198

Query: 199 ATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFREPQCFD- 257
             L V HKS +    DGLF  + KE+      ++  I+   +++D+ V  +   P  +  
Sbjct: 199 PKLVVVHKSTIQRLADGLFVTVAKEL----AHEFPDIQLQTELIDNTVLNVVSNPSKYSD 254

Query: 258 -VIVAPNLYGDILSDGAAAL-VGSLGVVPSANVGPEIVIGEPCHGSAPDIAGKGIANPIA 315
            V V PNLYGDILSD  + L  GSLG+ PS N+G ++ I E  HGSAPDIAG+  ANP A
Sbjct: 255 VVYVCPNLYGDILSDLNSGLSAGSLGLTPSGNIGHKVSIFEAVHGSAPDIAGQNKANPTA 314

Query: 316 TIRSTALMLEFLGHNGAAQDIYKAVDANLREGAIT-TPDLGGKASTQQVVDDVLSRL 371
            + S+ +ML  +G    A  I KAV   +  G  + T DL G AST    + V+SRL
Sbjct: 315 LLLSSVMMLNHMGLFEHASKIEKAVLTTIAAGPESRTGDLAGSASTSSFTEAVISRL 371

>Kpol_440.12 s440 (32084..33190) [1107 bp, 368 aa] {ON}
           (32084..33190) [1107 nt, 369 aa]
          Length = 368

 Score =  166 bits (421), Expect = 1e-47,   Method: Compositional matrix adjust.
 Identities = 127/389 (32%), Positives = 192/389 (49%), Gaps = 39/389 (10%)

Query: 1   MFRSVATRVSACRGLAT------------NAARKSLTIGLIPGDGIGKEVIPAGKQVLEN 48
           M R+   R S  R + T            N      T+  I GDG+G E+  + K +   
Sbjct: 1   MLRNTIYRGSFARMMTTGQPNIGRFTGKPNPVTGKYTVPFIEGDGVGPEISKSVKDIFAA 60

Query: 49  LNSKHGLSFNFIDLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSS 108
             +K  + +   D+   F     T   +PD  V  + K    AL G + +P  K  G+ S
Sbjct: 61  --AKVPIEWEPCDVGPIFVNGLTT---IPDAAVQSINKHLV-ALKGPLATPIGK--GHRS 112

Query: 109 PIVALRREMGLFANVRPVKSVEGSRN--KPIDMVIVRENTEDLYIKIEKTYIDKATGTRV 166
             + LR+   LFANVRP +SV   +   + +D+V++RENTE  Y  IE           V
Sbjct: 113 LNLTLRKTFNLFANVRPARSVPNYKTTYQNVDLVLIRENTEGEYSGIEH-----VISPGV 167

Query: 167 ADATKRISEIATRRIATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYE 226
             + K I++ A+ R+    +  A +  +  G   L V HKS +    DGLF  + KE+  
Sbjct: 168 IQSIKLITKDASERV----IRYAFEYTRAIGRPRLVVVHKSTIQRMADGLFVNVAKEL-- 221

Query: 227 SNKDKYGQIKYNEQIVDSMVYRLFREPQCFD--VIVAPNLYGDILSDGAAAL-VGSLGVV 283
               +Y  I+   +++D+ +  +   P+ +   V V PNLYGDILSD  + L  GSLG+ 
Sbjct: 222 --ASEYPDIELQTELIDNTILNVVTHPESYTDAVSVCPNLYGDILSDLNSGLSAGSLGLT 279

Query: 284 PSANVGPEIVIGEPCHGSAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDAN 343
           PSAN+G ++ I E  HGSAPDIAG+  ANP A + S+ +ML  +G N  A  I  A+ + 
Sbjct: 280 PSANIGDKVSIFEAVHGSAPDIAGQNKANPTALLLSSVMMLNHMGLNEHATKIENAILST 339

Query: 344 LREGAIT-TPDLGGKASTQQVVDDVLSRL 371
           +  G+   T DL G A+T    + V+++L
Sbjct: 340 IASGSENRTGDLAGTATTSSFTEAVINKL 368

>ZYRO0D11220g Chr4 (946652..947758) [1107 bp, 368 aa] {ON} highly
           similar to uniprot|P28241 Saccharomyces cerevisiae
           YOR136W IDH2 Subunit of mitochondrial NAD( )- dependent
           isocitrate dehydrogenase which catalyzes the oxidation
           of isocitrate to alpha-ketoglutarate in the TCA cycle
          Length = 368

 Score =  164 bits (415), Expect = 1e-46,   Method: Compositional matrix adjust.
 Identities = 122/352 (34%), Positives = 182/352 (51%), Gaps = 27/352 (7%)

Query: 26  IGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFIDLYAGFQTFQETGKALPDETVNVLK 85
           +  I GDGIG E+  + K +     +K  + F  + +            ++P+E    + 
Sbjct: 38  VSFIEGDGIGPEISKSVKDIFAA--AKVPVDFESVVVKP---ILVNGVTSIPEEAQKSIN 92

Query: 86  KQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLFANVRPVKSVEGSRN--KPIDMVIVR 143
                AL G + +P  K  G+ S  + LR+  GLFAN+RP KSVEG +     +++V++R
Sbjct: 93  TNLV-ALKGPLATPVGK--GHRSMNLTLRKTFGLFANLRPAKSVEGFKTIYDNVNLVLIR 149

Query: 144 ENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALKRLQTRGEATLTV 203
           ENTE  Y  IE   +       V  + K I+  A+ R+   A + A    + R    L V
Sbjct: 150 ENTEGEYAGIEHAIVPG-----VVQSIKLITREASERVIRFAYEYARAAERPR----LIV 200

Query: 204 THKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFREPQCFD--VIVA 261
            HKS +   +DGLF ++ KE+    + ++  IK   +++D+ V     +P  +   V V 
Sbjct: 201 VHKSTIQRLSDGLFVDVAKEL----QSEFPDIKLETELIDNAVLNTVTDPTKYSDAVSVC 256

Query: 262 PNLYGDILSDGAAAL-VGSLGVVPSANVGPEIVIGEPCHGSAPDIAGKGIANPIATIRST 320
           PNLYGDILSD  + L  GSLG+ PS N+G ++ I E  HGSAPDIAGK  ANP A + S+
Sbjct: 257 PNLYGDILSDMNSGLSAGSLGLTPSGNIGHKVSIFEAVHGSAPDIAGKDKANPTALLLSS 316

Query: 321 ALMLEFLGHNGAAQDIYKAVDANLREGAIT-TPDLGGKASTQQVVDDVLSRL 371
            +ML  +G +  A  I KAV   +  G  + T DL G AST    + V+ +L
Sbjct: 317 VMMLHHMGLHEHASQIEKAVLTTIAAGPESRTGDLKGSASTSSFTEAVIKKL 368

>KAFR0J01410 Chr10 complement(256693..257745) [1053 bp, 350 aa] {ON}
           Anc_2.278 YNL037C
          Length = 350

 Score =  162 bits (410), Expect = 5e-46,   Method: Compositional matrix adjust.
 Identities = 122/377 (32%), Positives = 195/377 (51%), Gaps = 37/377 (9%)

Query: 1   MFRSVATRVSACRGLATNAARK---SLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSF 57
           M R+   R    R ++T + +K      I LIPG+GIGKEV  + + + +  N    + +
Sbjct: 1   MLRNTLLR----RSISTISPKKYGGRFQITLIPGNGIGKEVTDSVRSIFQAENLP--IDW 54

Query: 58  NFIDLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREM 117
             +++    ++ ++  K   D       K+ + AL G   S    ++G  S  VALR+++
Sbjct: 55  EIVNI----ESHRDGIKTAVDSI-----KRNKIALKGIWSS--DPIDG--SLNVALRKQL 101

Query: 118 GLFANVRPVKSVEG--SRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISE 175
            +FANV   KS +   +R   +D+V++RENTE  +  +E   +D      V ++ K +++
Sbjct: 102 DIFANVAIFKSFDNVNTRIPNVDLVVIRENTEGEFSGLEHESVDG-----VVESLKIVTK 156

Query: 176 IATRRIATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQI 235
             T RIA  A D A K  +      +T  HK+N++   DGLF+ I   +     ++Y +I
Sbjct: 157 PKTERIARFAFDFAKKHNRNH----VTAVHKANIMKLGDGLFKNIVAHI---GNNEYPEI 209

Query: 236 KYNEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIG 295
           K +  IVD+   +   +P  FDV+V+P++YG IL +  AAL+G  G+VP AN G +  + 
Sbjct: 210 KNSSIIVDNASMQAVAKPHQFDVLVSPSMYGTILGNIGAALIGGPGLVPGANFGRDYAVF 269

Query: 296 EP-CHGSAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAITTPDL 354
           EP       DI G+ +ANP A I S   ML  LG    A+ I  AV   + +G   T D+
Sbjct: 270 EPGSRHVGLDIKGQNVANPTAMILSATWMLRHLGLTSPAERITNAVKHVIAQGTTVTKDI 329

Query: 355 GGKASTQQVVDDVLSRL 371
           GG AST +  D V++ L
Sbjct: 330 GGTASTTEFTDAVINEL 346

>TPHA0E01480 Chr5 complement(300222..301355) [1134 bp, 377 aa] {ON}
           Anc_5.473 YOR136W
          Length = 377

 Score =  156 bits (394), Expect = 2e-43,   Method: Compositional matrix adjust.
 Identities = 118/360 (32%), Positives = 183/360 (50%), Gaps = 28/360 (7%)

Query: 18  NAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFIDLYAGFQTFQETGKALP 77
           N    + T+  I GDG+G E+  + + + +   +K  + +   D+       + T   +P
Sbjct: 39  NPETGNYTVPFIEGDGVGPEISKSVRTIFKA--AKVPIDWVNCDIGPLLINGETT---IP 93

Query: 78  DETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLFANVRPVKSVE--GSRNK 135
              V+ +      AL G + +P    +G+ S  + LR+  GLFANVRP KS+    S  +
Sbjct: 94  QTAVDQINNSLI-ALKGPLATPVG--QGHRSINLTLRKTFGLFANVRPAKSIPNLASTYE 150

Query: 136 PIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALKRLQT 195
            +D++++RENTE  Y  IE   +       V  + K I+  A+ ++    +  A +  ++
Sbjct: 151 NVDLIVIRENTEGEYSGIEHEIVPG-----VVQSIKLITRKASEKV----IKYAFEYTRS 201

Query: 196 RGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFREPQC 255
            G + L V HK+ +  + DGLF +  +E+     DKY  +    +++D+ V      P+ 
Sbjct: 202 IGRSNLIVVHKATIQRRGDGLFVQTAQEM----ADKYPDVNLKLELIDNTVLNCIMNPEK 257

Query: 256 F--DVIVAPNLYGDILSDGAAAL-VGSLGVVPSANVGPEIVIGEPCHGSAPDIAGKGIAN 312
           +   V V PNLYGDILSD  + L  GSLG+ PSAN+G E V+ E  HGSAPDIAG+  AN
Sbjct: 258 YADSVSVCPNLYGDILSDLNSGLSTGSLGLTPSANIG-ETVLYEAVHGSAPDIAGQDKAN 316

Query: 313 PIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGA-ITTPDLGGKASTQQVVDDVLSRL 371
           P A + S+ +ML  +G    A  I  AV   +  G    T DLGG A+T      V+  L
Sbjct: 317 PTALLLSSVMMLNHMGLQKYADMIETAVLTTITSGKEFRTADLGGSATTTSFTKAVIENL 376

>TBLA0C01500 Chr3 complement(347212..348309) [1098 bp, 365 aa] {ON}
           Anc_1.402 YCL018W
          Length = 365

 Score =  153 bits (386), Expect = 2e-42,   Method: Compositional matrix adjust.
 Identities = 125/369 (33%), Positives = 189/369 (51%), Gaps = 38/369 (10%)

Query: 25  TIGLIPGDGIGKEVIPAGKQVLENLNSK-HGLSFNFIDLYAGFQTFQETGKALPDETVNV 83
            I ++PGD +G+E++    +VL+ +  K HG+ FNF     G     +TG  LPDET+  
Sbjct: 6   NIVVLPGDHVGQEIVEEAVKVLKIVEEKRHGVKFNFQYHLIGGDAIDKTGDPLPDETLEA 65

Query: 84  LKKQCQGALFGAVQSP---TTKVEGYSSPIVALRREMGLFANVRPVKSVEGSR------- 133
             KQ    L GAV  P   T KV      ++ +R+E+GL+ N+RP K +           
Sbjct: 66  -AKQSDAVLLGAVGGPKWGTGKVRPEQG-LLKIRKELGLYGNLRPCKFISDKLIGLSPLK 123

Query: 134 ---NKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIAL 190
               K  D V+VRE    +Y   E+   D   G+ VA  +++ S    +RI  +A   A 
Sbjct: 124 EEVCKGTDFVVVRELVGGIYFG-ERQEDD---GSGVAWDSEKYSIEEVKRITKMA---AF 176

Query: 191 KRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLF 250
             LQ      +    K+NVL+ +  L+R    E       ++  +K   Q++DS    L 
Sbjct: 177 LSLQNDPPLPIWSLDKANVLASSR-LWRAAVDETIA----EFPNLKVQHQLIDSAAMMLV 231

Query: 251 REP-QCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVG--PE----IVIGEPCHGSAP 303
           + P Q   +I+  N++GDI+SD A+ + GSLG++PSA++   P+      + EPCHGSAP
Sbjct: 232 KNPTQLNGIILTNNMFGDIISDEASVIPGSLGLLPSASLASLPDKNKAFGLYEPCHGSAP 291

Query: 304 DIAGKGIANPIATIRSTALMLEF-LGHNGAAQDIYKAVDANLREGAITTPDLGGKASTQQ 362
           D+A +G  NP+ATI S A+ML+  L      + I +AV   L  G I T DLGG ++T +
Sbjct: 292 DLA-RGKVNPVATILSAAMMLKLSLDMVQEGEAIERAVSVVLDRG-IRTADLGGNSTTSE 349

Query: 363 VVDDVLSRL 371
           + D V   L
Sbjct: 350 LGDAVAQEL 358

>KNAG0A05280 Chr1 (780448..781533) [1086 bp, 361 aa] {ON} 
          Length = 361

 Score =  152 bits (384), Expect = 4e-42,   Method: Compositional matrix adjust.
 Identities = 116/374 (31%), Positives = 184/374 (49%), Gaps = 31/374 (8%)

Query: 8   RVSACRGLAT-------NAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFI 60
           R+ + R LAT       N      T+ L+PGDG+GKE   +   V    N    + +  +
Sbjct: 4   RLVSKRSLATLPETLFPNKYGGRYTVTLLPGDGVGKECTDSVVSVFNAENIP--IDWEIV 61

Query: 61  DLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLF 120
           ++ +G    +    A     V  L++   G L G   +      G+ S  VA R+++ ++
Sbjct: 62  NI-SGLDHKEGVAAA-----VQSLRRNKIG-LKGLWHTSNADQSGHGSLNVAFRKQLDIY 114

Query: 121 ANVRPVKSVEGSRNK--PIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIAT 178
           ANV   KS++G +     +D+V++RENTE  +  +E   ++      V ++ K  +   T
Sbjct: 115 ANVAVFKSLKGVKTMIPDVDLVVIRENTEGEFSGLEHESVEG-----VVESLKVTTLPKT 169

Query: 179 RRIATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYN 238
            RIA  A + A    Q  G   +   HK+N++   DGLFR     + E    +Y  I+ +
Sbjct: 170 ERIARFAFNYA----QKNGRKAVCAVHKANIMKLGDGLFRNTVTSIGEK---EYPDIETS 222

Query: 239 EQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEP- 297
             IVD+   +   +P  FDV+V P++YG I+ +  AAL+G  G+V  AN G E  + EP 
Sbjct: 223 SIIVDNASMQAVAKPHQFDVLVTPSMYGTIIGNIGAALIGGPGLVAGANFGREYAVFEPG 282

Query: 298 CHGSAPDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGK 357
                 DI G+ IANP A + S+ALML  LG   + + I  AV   + EG + T D+GG 
Sbjct: 283 SRHVGLDIKGQNIANPTAMLLSSALMLNHLGLTKSGKRISDAVREVIAEGDVRTKDIGGD 342

Query: 358 ASTQQVVDDVLSRL 371
           A+T +    V+ +L
Sbjct: 343 ATTTEFTQAVIEKL 356

>TDEL0B06000 Chr2 (1060828..1061916) [1089 bp, 362 aa] {ON}
           Anc_1.402 YCL018W
          Length = 362

 Score =  144 bits (363), Expect = 4e-39,   Method: Compositional matrix adjust.
 Identities = 124/369 (33%), Positives = 189/369 (51%), Gaps = 41/369 (11%)

Query: 23  SLTIGLIPGDGIGKEVIPAGKQVLENLNS-KHGLSFNFIDLYAGFQTFQETGKALPDETV 81
           S  I ++PGD +G+E+     +VL+ ++  +   +FNF     G      TG  LPDE +
Sbjct: 2   SKNIVVLPGDHVGQEITEEAIKVLKAISEVRPNATFNFQHHLIGGAAIDATGVPLPDEAL 61

Query: 82  NVLKKQCQGALFGAVQSPTTKVEGYSSP---IVALRREMGLFANVRP----------VKS 128
              KK     L GAV  P     G   P   ++ +R+E+ L+AN+RP          +  
Sbjct: 62  EASKK-ADAVLLGAVGGPKWGT-GAVRPEQGLLKIRKELQLYANLRPCNFASDSLLELSP 119

Query: 129 VEGSRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDI 188
           ++    +  D V+VRE    +Y    K    +  G  VA  +++ S    +RI  +A   
Sbjct: 120 LKAQYAQGTDFVVVRELVGGIYFGERK----EDEGDGVAWDSEQYSVPEVQRITRMA--- 172

Query: 189 ALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYR 248
           A   LQ      +    K+NVL+ +  L+R   K V ++ K+++  +  N Q++DS    
Sbjct: 173 AFLALQHNPPLPIWSLDKANVLASSR-LWR---KTVEKTIKEEFPTLSVNHQLIDSAAMI 228

Query: 249 LFREP-QCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVG--PE----IVIGEPCHGS 301
           L + P Q   +I+  N++GDI+SD A+ + GSLG++PSA++   P+      + EPCHGS
Sbjct: 229 LVKNPTQLNGIIITSNMFGDIISDEASVIPGSLGLLPSASLASLPDTNTAFGLYEPCHGS 288

Query: 302 APDIAGKGIANPIATIRSTALMLEF---LGHNGAAQDIYKAVDANLREGAITTPDLGGKA 358
           APD+A KG  NP+ATI S A+ML+    +   G A  I KAV   L +G I T DLGG  
Sbjct: 289 APDLA-KGKVNPVATILSAAMMLKLSLNMVEEGVA--IEKAVKKVLDDG-IRTGDLGGSN 344

Query: 359 STQQVVDDV 367
           ST +V D V
Sbjct: 345 STSEVGDAV 353

>Ecym_1296 Chr1 (602530..603621) [1092 bp, 363 aa] {ON} similar to
           Ashbya gossypii AAL012C
          Length = 363

 Score =  143 bits (360), Expect = 1e-38,   Method: Compositional matrix adjust.
 Identities = 125/366 (34%), Positives = 184/366 (50%), Gaps = 37/366 (10%)

Query: 28  LIPGDGIGKEVIPAGKQVLENLN-SKHGLSFNFIDLYAGFQTFQETGKALPDETVNVLKK 86
           ++PGD IG+EVI    +VL  +  ++  ++F F     G      TG  L D+T+    K
Sbjct: 9   VLPGDYIGQEVIAETIKVLNAIQEARPSINFEFEYHLIGGAAINATGAPLSDKTIEA-AK 67

Query: 87  QCQGALFGAVQSPTTKVEGYSSP---IVALRREMGLFANVRPV----KSVEG-SRNKP-- 136
                L GAV  P     G   P   ++A+R+E+GL+AN+RP     KS+ G S  KP  
Sbjct: 68  AADAVLLGAVGGPEWD-SGAVRPEQGLLAIRKELGLYANLRPCSFISKSLLGLSPLKPEI 126

Query: 137 ---IDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALKRL 193
               D VI+RE    +Y    K   D   G         +SE+   RI  +    A   L
Sbjct: 127 AQGTDFVILRELVGGIYFGERKE--DDGDGVAWDSEKYTVSEV--ERITRMG---AFLAL 179

Query: 194 QTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFREP 253
           Q      L    K+NVL+ +  L+R   + V E+ K ++ Q+    Q++DS    + + P
Sbjct: 180 QHDPPLPLWSFDKANVLASSR-LWR---RTVNETIKREFPQLSVQHQLIDSAAMIMIKNP 235

Query: 254 QCFD-VIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE------IVIGEPCHGSAPDIA 306
           + F+ +++  N++GDI+SD A+ + GSLG++PSA++  E        + EPCHGSAPD+ 
Sbjct: 236 RKFNGIVITSNIFGDIISDAASVIPGSLGLLPSASLASEPDKNNAFGLYEPCHGSAPDLE 295

Query: 307 GKGIANPIATIRSTALMLEF-LGHNGAAQDIYKAVDANLREGAITTPDLGGKASTQQVVD 365
            KG ANPIA I S A+ML+  L      + I  AV   +  G I T DLGG  +T +V D
Sbjct: 296 -KGQANPIACILSAAMMLKLSLNMVDEGKAIENAVKQVIESG-IRTGDLGGNNTTTEVGD 353

Query: 366 DVLSRL 371
            V   L
Sbjct: 354 AVTHAL 359

>AAL012C Chr1 complement(320148..321266) [1119 bp, 372 aa] {ON}
           Syntenic homolog of Saccharomyces cerevisiae YCL018W
           (LEU2)
          Length = 372

 Score =  143 bits (360), Expect = 1e-38,   Method: Compositional matrix adjust.
 Identities = 124/368 (33%), Positives = 196/368 (53%), Gaps = 45/368 (12%)

Query: 26  IGLIPGDGIGKEVIPAGKQVL----ENLNSKHGLSFNFIDLYAGFQTFQETGKALPDETV 81
           I ++PGD IG+EV+    +VL    ++L+  H   F+F     G      TG ALPDE +
Sbjct: 7   IVVLPGDHIGREVVEEAVKVLGAVEQSLSDVH---FDFQYHLVGGAAIDATGSALPDEAL 63

Query: 82  NVLKKQCQGALFGAVQSPTTKVEGYSSP---IVALRREMGLFANVRPVKS-----VEGSR 133
               K+    L GAV  P  +  G   P   ++ LR+E+G++AN+RP        +E S 
Sbjct: 64  GA-AKEADAVLLGAVGGPKWQ-GGAVRPEQGLLKLRQELGVYANLRPCNFAADSLLELSP 121

Query: 134 NKP-----IDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDI 188
            +P      D+++VRE     Y    + + D+  G  VA  T + +    +RIA +A  +
Sbjct: 122 LRPEIARDTDIMVVRELLGGSYFG--ERHEDEGDG--VAWDTDKYTVKEVQRIARMAGFL 177

Query: 189 ALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYR 248
           AL   Q      +    K+NVL+ +  L+R+  +E ++S   ++  ++   Q++DS    
Sbjct: 178 AL---QHDPPLPVWSLDKANVLASSR-LWRKTVEETFQS---EFPNVQLQHQLIDSAAMI 230

Query: 249 LFREPQCFD-VIVAPNLYGDILSDGAAALVGSLGVVPSANVG--PE----IVIGEPCHGS 301
           L + P+ F+ V+V  N++GDI+SD A+ + GSLG++PSA++   P+      + EPCHGS
Sbjct: 231 LVKNPRAFNGVVVTSNMFGDIISDEASVIPGSLGLLPSASLASLPDSKSAFGLYEPCHGS 290

Query: 302 APDI-AGKGIANPIATIRSTALMLEF-LGHNGAAQDIYKAVDANLREGAITTPDLGGKAS 359
           APD+ AGK  ANPI  I S A+ML+  L    A + + +AV   L  G + T DL G +S
Sbjct: 291 APDLPAGK--ANPIGCILSAAMMLKLSLNMVAAGEAVEQAVQEVLDSG-VRTGDLLGSSS 347

Query: 360 TQQVVDDV 367
           T +V D +
Sbjct: 348 TSEVGDAI 355

>KLLA0D04906g Chr4 (420903..421991) [1089 bp, 362 aa] {ON} highly
           similar to uniprot|P04173 Saccharomyces cerevisiae
           YCL018W LEU2 Beta-isopropylmalate dehydrogenase
           catalyzes the third step in the leucine biosynthesis
           pathway
          Length = 362

 Score =  142 bits (357), Expect = 3e-38,   Method: Compositional matrix adjust.
 Identities = 122/371 (32%), Positives = 184/371 (49%), Gaps = 45/371 (12%)

Query: 23  SLTIGLIPGDGIGKEVIPAGKQVLENLNS-KHGLSFNFIDLYAGFQTFQETGKALPDETV 81
           S  I ++PGD +GKEV     +VL  +   +  + FNF     G      TG  LPDE +
Sbjct: 2   SKNIVVLPGDHVGKEVTDEAIKVLNAIAEVRPEIKFNFQHHLIGGAAIDATGTPLPDEAL 61

Query: 82  NVLKKQCQGALFGAVQSPTTKVEGYSSP---IVALRREMGLFANVRP----------VKS 128
              KK     L GAV  P     G   P   ++ +R+E+GL+AN+RP          +  
Sbjct: 62  EASKK-ADAVLLGAVGGPKWGT-GAVRPEQGLLKIRKELGLYANLRPCNFASDSLLDLSP 119

Query: 129 VEGSRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDI 188
           ++    K  D V+VRE    +Y    K    +  G  VA  +++ S    +RI  +A   
Sbjct: 120 LKPEYAKGTDFVVVRELVGGIYFGERK----EDEGDGVAWDSEKYSVPEVQRITRMA--- 172

Query: 189 ALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYR 248
           A   LQ      +    K+NVL+ +  L+R   K V E+ K ++ Q+    Q++DS    
Sbjct: 173 AFLALQQNPPLPIWSLDKANVLASSR-LWR---KTVEETIKTEFPQLTVQHQLIDSAAMI 228

Query: 249 LFREPQCFD-VIVAPNLYGDILSDGAAALVGSLGVVPSANVG--PE----IVIGEPCHGS 301
           L + P   + V++  N++GDI+SD A+ + GSLG++PSA++   P+      + EPCHGS
Sbjct: 229 LVKSPTKLNGVVITNNMFGDIISDEASVIPGSLGLLPSASLASLPDTNKAFGLYEPCHGS 288

Query: 302 APDIAGKGIANPIATIRSTALMLEF---LGHNGAA--QDIYKAVDANLREGAITTPDLGG 356
           APD+    + NPIATI S A+ML+    L   G A  + +   +DA +R G     DLGG
Sbjct: 289 APDLPANKV-NPIATILSAAMMLKLSLDLVEEGRALEEAVRNVLDAGVRTG-----DLGG 342

Query: 357 KASTQQVVDDV 367
             ST +V D +
Sbjct: 343 SNSTTEVGDAI 353

>Kpol_1048.63 s1048 (182096..183190) [1095 bp, 364 aa] {ON}
           (182096..183190) [1095 nt, 365 aa]
          Length = 364

 Score =  141 bits (356), Expect = 4e-38,   Method: Compositional matrix adjust.
 Identities = 123/369 (33%), Positives = 185/369 (50%), Gaps = 46/369 (12%)

Query: 26  IGLIPGDGIGKEVIPAGKQVLENL--NSKHGLSFNFIDLYAGFQTFQETGKALPDETVNV 83
           I ++PGD +G+E++    +VLE +  +S  G+ F F     G  +   TG  LPDE ++ 
Sbjct: 6   IVVLPGDHVGEEIVDEAIKVLEAVASSSSKGIKFEFQRHLIGGASIDATGTPLPDEALDA 65

Query: 84  LKKQCQGALFGAVQSPTTKVEGYSSP---IVALRREMGLFANVRPVKSVEGSR------- 133
             K     L GAV  P     G   P   ++ +R+E+ L+AN+RP   V  S        
Sbjct: 66  -AKNSDAVLLGAVGGPKWGT-GDVRPEQGLLKIRKELQLYANLRPCNFVSDSLLGLSPLK 123

Query: 134 ---NKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIAL 190
               K  D  +VRE    +Y    K   D   G+        I E+  +RI  +A   A 
Sbjct: 124 EEIAKGTDFTVVRELVGGIYFGDRKE--DDGDGSAWDCEKYTIPEV--QRITRMA---AF 176

Query: 191 KRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLF 250
             LQ      +    K+NVL+ +  L+R   K V E+ K+++  +K   Q++DS    L 
Sbjct: 177 LALQHDPPLPIWSLDKANVLASSR-LWR---KTVEETIKNEFPNLKVQHQLIDSAAMILV 232

Query: 251 REPQCFD-VIVAPNLYGDILSDGAAALVGSLGVVPSANVG--PE----IVIGEPCHGSAP 303
           + P+  + +I+  N++GDI+SD A+ + GSLG++PSA++   P+      + EPCHGSAP
Sbjct: 233 KSPRQLNGIIITNNMFGDIISDEASVIPGSLGLLPSASLASLPDTNTAFGLYEPCHGSAP 292

Query: 304 DIAGKGIANPIATIRSTALMLEF---LGHNGAA--QDIYKAVDANLREGAITTPDLGGKA 358
           D+  KG  NPIATI S A+ML+    L   G A  Q + + +DA +R     T DL G  
Sbjct: 293 DLP-KGKVNPIATILSAAMMLKLSLNLVDEGIAIEQAVKQVLDAGIR-----TADLKGSN 346

Query: 359 STQQVVDDV 367
           ST +V D V
Sbjct: 347 STSEVGDAV 355

>Smik_3.66 Chr3 (89718..90812) [1095 bp, 364 aa] {ON} YCL018W (REAL)
          Length = 364

 Score =  141 bits (355), Expect = 6e-38,   Method: Compositional matrix adjust.
 Identities = 119/368 (32%), Positives = 188/368 (51%), Gaps = 45/368 (12%)

Query: 26  IGLIPGDGIGKEVIPAGKQVLENLNS-KHGLSFNFIDLYAGFQTFQETGKALPDETVNVL 84
           I ++PGD +G+E+     +VL+ ++  +  ++F+F +   G      TG  LPDE +   
Sbjct: 7   IVVLPGDHVGQEITAEAIKVLKAISEVRSDVNFDFENHLIGGAAIDATGVPLPDEALEAS 66

Query: 85  KKQCQGALFGAVQSPTTKVEGYSSP---IVALRREMGLFANVRP----------VKSVEG 131
           KK     L GAV  P     G   P   ++ +R+E+ L+AN+RP          +  ++ 
Sbjct: 67  KK-ADAVLLGAVGGPKWGT-GSVRPEQGLLKIRKELQLYANLRPCNFASDSLLDLSPIKP 124

Query: 132 SRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALK 191
              K  D V+VRE    +Y    K    +  G  VA  +++ +    +RI  +A   A  
Sbjct: 125 QFAKGTDFVVVRELVGGIYFGKRK----EDDGDGVAWDSEQYTVPEVQRITRMA---AFM 177

Query: 192 RLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFR 251
            LQ      +    K+NVL+ +  L+R   K V E+ K+++  +K   Q++DS    L +
Sbjct: 178 ALQHEPPLPIWSLDKANVLASSR-LWR---KTVEETIKNEFPTLKVQHQLIDSAAMILVK 233

Query: 252 EPQCFD-VIVAPNLYGDILSDGAAALVGSLGVVPSANVG--PE----IVIGEPCHGSAPD 304
            P   + +I+  N++GDI+SD A+ + GSLG++PSA++   P+      + EPCHGSAPD
Sbjct: 234 NPTHLNGIIITSNMFGDIISDEASVIPGSLGLLPSASLASLPDKNTAFGLYEPCHGSAPD 293

Query: 305 IAGKGIANPIATIRSTALMLEF---LGHNGAAQD--IYKAVDANLREGAITTPDLGGKAS 359
           +  K   NPIATI S A+ML+    L   G A +  + K +DA +R G     DLGG  S
Sbjct: 294 LP-KNKVNPIATILSAAMMLKLSLNLPEEGKAIEDAVKKVLDAGIRTG-----DLGGSNS 347

Query: 360 TQQVVDDV 367
           T +V D V
Sbjct: 348 TTEVGDAV 355

>YCL018W Chr3 (91324..92418) [1095 bp, 364 aa] {ON}
           LEU2Beta-isopropylmalate dehydrogenase (IMDH), catalyzes
           the third step in the leucine biosynthesis pathway
          Length = 364

 Score =  141 bits (355), Expect = 6e-38,   Method: Compositional matrix adjust.
 Identities = 119/368 (32%), Positives = 187/368 (50%), Gaps = 45/368 (12%)

Query: 26  IGLIPGDGIGKEVIPAGKQVLENLNS-KHGLSFNFIDLYAGFQTFQETGKALPDETVNVL 84
           I ++PGD +G+E+     +VL+ ++  +  + F+F +   G      TG  LPDE +   
Sbjct: 7   IVVLPGDHVGQEITAEAIKVLKAISDVRSNVKFDFENHLIGGAAIDATGVPLPDEALEAS 66

Query: 85  KKQCQGALFGAVQSPTTKVEGYSSP---IVALRREMGLFANVRP----------VKSVEG 131
           KK     L GAV  P     G   P   ++ +R+E+ L+AN+RP          +  ++ 
Sbjct: 67  KK-ADAVLLGAVGGPKWGT-GSVRPEQGLLKIRKELQLYANLRPCNFASDSLLDLSPIKP 124

Query: 132 SRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALK 191
              K  D V+VRE    +Y    K    +  G  VA  +++ +    +RI  +A   A  
Sbjct: 125 QFAKGTDFVVVRELVGGIYFGKRK----EDDGDGVAWDSEQYTVPEVQRITRMA---AFM 177

Query: 192 RLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFR 251
            LQ      +    K+NVL+ +  L+R   K V E+ K+++  +K   Q++DS    L +
Sbjct: 178 ALQHEPPLPIWSLDKANVLASSR-LWR---KTVEETIKNEFPTLKVQHQLIDSAAMILVK 233

Query: 252 EPQCFD-VIVAPNLYGDILSDGAAALVGSLGVVPSANVG--PE----IVIGEPCHGSAPD 304
            P   + +I+  N++GDI+SD A+ + GSLG++PSA++   P+      + EPCHGSAPD
Sbjct: 234 NPTHLNGIIITSNMFGDIISDEASVIPGSLGLLPSASLASLPDKNTAFGLYEPCHGSAPD 293

Query: 305 IAGKGIANPIATIRSTALMLEF---LGHNGAAQD--IYKAVDANLREGAITTPDLGGKAS 359
           +  K   NPIATI S A+ML+    L   G A +  + K +DA +R G     DLGG  S
Sbjct: 294 LP-KNKVNPIATILSAAMMLKLSLNLPEEGKAIEDAVKKVLDAGIRTG-----DLGGSNS 347

Query: 360 TQQVVDDV 367
           T +V D V
Sbjct: 348 TTEVGDAV 355

>KLTH0H12188g Chr8 (1039347..1040441) [1095 bp, 364 aa] {ON} highly
           similar to uniprot|P04173 Saccharomyces cerevisiae
           YCL018W LEU2 Beta-isopropylmalate dehydrogenase
           catalyzes the third step in the leucine biosynthesis
           pathway
          Length = 364

 Score =  139 bits (350), Expect = 3e-37,   Method: Compositional matrix adjust.
 Identities = 117/368 (31%), Positives = 186/368 (50%), Gaps = 45/368 (12%)

Query: 26  IGLIPGDGIGKEVIPAGKQVLENLNS-KHGLSFNFIDLYAGFQTFQETGKALPDETVNVL 84
           I ++PGD +G+E+     +VL+ ++  +  + F F     G      TG+ LPD ++   
Sbjct: 7   IVVLPGDHVGQEITDEAIKVLKAISEVRSSVKFEFQQHLIGGAAIDATGEPLPDASLEAA 66

Query: 85  KKQCQGALFGAVQSPTTKVEGYSSP---IVALRREMGLFANVRP----------VKSVEG 131
           KK     L GAV  P     G   P   ++ +R+E+ L+AN+RP          +  ++ 
Sbjct: 67  KK-ADAVLLGAVGGPKWGT-GAVRPEQGLLKIRKELQLYANLRPCNFASESLLDLSPLKA 124

Query: 132 SRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALK 191
              +  D V+VRE    +Y    K    +  G  VA  +++ S    +RI  +A   A  
Sbjct: 125 EHARGTDFVVVRELVGGIYFGERK----EDEGDGVAWDSEKYSVPEVQRITRMA---AFL 177

Query: 192 RLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFR 251
            LQ      +    K+NVL+ +  L+R   K V E+ K+++  +    Q++DS    + +
Sbjct: 178 ALQHNPPLPVWSLDKANVLASSR-LWR---KTVEETIKNEFPTLTVQHQLIDSAAMIMVK 233

Query: 252 EP-QCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVG--PE----IVIGEPCHGSAPD 304
            P Q   VI+  N++GDI+SD A+ + GSLG++PSA++   P+      + EPCHGSAPD
Sbjct: 234 NPTQLNGVIITNNMFGDIISDEASVIPGSLGLLPSASLASLPDTNTAFGLYEPCHGSAPD 293

Query: 305 IAGKGIANPIATIRSTALMLEF---LGHNGAA--QDIYKAVDANLREGAITTPDLGGKAS 359
           +  KG  NPIATI S A+MLE    +   G A  + + + +D+ +R G     DL G  S
Sbjct: 294 LE-KGKVNPIATILSAAMMLELSLDMFEEGTAVEEAVRRVLDSGIRTG-----DLRGSNS 347

Query: 360 TQQVVDDV 367
           TQ+V D V
Sbjct: 348 TQEVGDAV 355

>NDAI0G04230 Chr7 complement(1015689..1016780) [1092 bp, 363 aa]
           {ON} Anc_1.402
          Length = 363

 Score =  138 bits (348), Expect = 5e-37,   Method: Compositional matrix adjust.
 Identities = 120/368 (32%), Positives = 184/368 (50%), Gaps = 45/368 (12%)

Query: 26  IGLIPGDGIGKEVIPAGKQVLENLNS-KHGLSFNFIDLYAGFQTFQETGKALPDETVNVL 84
           I ++PGD +G+E+     +VL+ +    + ++F+F     G      TG  LPDE +   
Sbjct: 6   IVVLPGDHVGEEITAEAVKVLKAIAEVDNSINFDFQYHLIGGAAIDATGVPLPDEALEA- 64

Query: 85  KKQCQGALFGAVQSPTTKVEGYSSP---IVALRREMGLFANVRPVKSVEGSR-------- 133
            K     L GAV  P     G   P   ++ +R+E+GL+AN+RP      S         
Sbjct: 65  SKNSDAVLLGAVGGPKWGT-GAVRPEQGLLKIRKELGLYANLRPCNFASESLLGLSPLRP 123

Query: 134 --NKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALK 191
              K  D ++VRE    +Y    K    +  G  VA  +++ S    +RI  +A   A  
Sbjct: 124 EIAKGTDFMVVRELVGGIYFGKRK----EDEGDGVAWDSEQYSVPEVQRITRMA---AFL 176

Query: 192 RLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFR 251
            LQ      +    K+NVL+ +  L+R   K V E+ K+++  +    Q++DS    L +
Sbjct: 177 ALQHNPPLPIWSLDKANVLASSR-LWR---KTVEETIKNEFPTLTVQNQLIDSAAMILVK 232

Query: 252 EP-QCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVG--PE----IVIGEPCHGSAPD 304
            P Q   +I+  N++GDI+SD A+ + GSLG++PSA++   P+      + EPCHGSAPD
Sbjct: 233 NPTQLNGIIITSNMFGDIISDEASVIPGSLGLLPSASLASLPDTNTAFGLYEPCHGSAPD 292

Query: 305 IAGKGIANPIATIRSTALMLEF---LGHNGAA--QDIYKAVDANLREGAITTPDLGGKAS 359
           +  KG  NPIATI S A+ML+    L   G A  + + K +DA +R G     DLGG  S
Sbjct: 293 LP-KGKVNPIATILSAAMMLKLSLNLVKQGDAIEEAVKKVLDAGIRTG-----DLGGSNS 346

Query: 360 TQQVVDDV 367
           T +V D +
Sbjct: 347 TTEVGDAI 354

>Skud_3.43 Chr3 (70293..71387) [1095 bp, 364 aa] {ON} YCL018W (REAL)
          Length = 364

 Score =  138 bits (348), Expect = 7e-37,   Method: Compositional matrix adjust.
 Identities = 117/368 (31%), Positives = 186/368 (50%), Gaps = 45/368 (12%)

Query: 26  IGLIPGDGIGKEVIPAGKQVLENLNS-KHGLSFNFIDLYAGFQTFQETGKALPDETVNVL 84
           I ++PGD +G+E+     +VL+ ++  +  + F+F +   G      TG  LPDE +   
Sbjct: 7   IVVLPGDHVGQEITAEAIKVLKAISDVRSNVKFDFENHLIGGAAIDATGVPLPDEALEAS 66

Query: 85  KKQCQGALFGAVQSPTTKVEGYSSP---IVALRREMGLFANVRP----------VKSVEG 131
           KK     L GAV  P     G   P   ++ +R+E+ L+AN+RP          +  ++ 
Sbjct: 67  KK-ADAVLLGAVGGPKWGT-GSVRPEQGLLKIRKELQLYANLRPCNFASESLLDLSPIKP 124

Query: 132 SRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALK 191
              K  D V+VRE    +Y    K    +  G  VA   ++ +    +RI  +A   A  
Sbjct: 125 QFAKGTDFVVVRELVGGIYFGERK----EDDGDGVAWDCEQYTVPEVQRITRMA---AFM 177

Query: 192 RLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFR 251
            LQ      +    K+NVL+ +  L+R   K V E+ K+++  +K   Q++DS    L +
Sbjct: 178 ALQHEPPLPIWSLDKANVLASSR-LWR---KTVEETIKNEFPTLKVQHQLIDSAAMILVK 233

Query: 252 EPQCFD-VIVAPNLYGDILSDGAAALVGSLGVVPSANVG--PE----IVIGEPCHGSAPD 304
            P   + +I+  N++GDI+SD A+ + GSLG++PSA++   P+      + EPCHGSAPD
Sbjct: 234 NPTHLNGIIITSNMFGDIISDEASVIPGSLGLLPSASLASLPDKNTAFGLYEPCHGSAPD 293

Query: 305 IAGKGIANPIATIRSTALMLEF---LGHNGAAQD--IYKAVDANLREGAITTPDLGGKAS 359
           +  K   NP+ATI S A+ML+    L   G A +  + + +DA +R G     DLGG  S
Sbjct: 294 LP-KNKVNPVATILSAAMMLKLSLNLPEEGKAIEDAVKRVLDAGIRTG-----DLGGSNS 347

Query: 360 TQQVVDDV 367
           T +V D V
Sbjct: 348 TTEVGDAV 355

>Suva_14.302 Chr14 (546468..547370) [903 bp, 300 aa] {ON} YNL037C
           (REAL)
          Length = 300

 Score =  136 bits (343), Expect = 7e-37,   Method: Compositional matrix adjust.
 Identities = 106/318 (33%), Positives = 164/318 (51%), Gaps = 34/318 (10%)

Query: 8   RVSACRGLATNAARKSL---------TIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFN 58
           R  A R LAT A  + +         T+ LIPGDG+GKEV  + K + E  N    + + 
Sbjct: 4   RTIAKRSLATAAQVEHILPKKYGGRFTVTLIPGDGVGKEVTDSVKTIFEAENIP--IDWE 61

Query: 59  FIDLYAGFQTFQETGKALPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSPIVALRREMG 118
            I++    QT  + G    +E V  L++   G L G   +P  +  G+ S  VALR+++ 
Sbjct: 62  TINIK---QTDHKEGV---NEAVESLRRNKIG-LKGLWHTPADQT-GHGSLNVALRKQLD 113

Query: 119 LFANVRPVKSVEG--SRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEI 176
           ++ANV   KS++G  +R   ID++++RENTE  +  +E   +       V ++ K +++ 
Sbjct: 114 IYANVALFKSLKGVKTRIPDIDLIVIRENTEGEFSGLEHESVPG-----VVESLKIMTKP 168

Query: 177 ATRRIATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIK 236
            T RIA  A D A K         +T  HK+N++   DGLFR I  E+    + +Y  I 
Sbjct: 169 KTERIARFAFDFAKKY----NRKAVTAVHKANIMKLGDGLFRNIITEI---GQKEYPDID 221

Query: 237 YNEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGE 296
            +  IVD+   +   +P  FDV+V P++YG IL +  AAL+G  G+V  AN G +  + E
Sbjct: 222 VSSIIVDNASMQAVAKPHQFDVLVTPSMYGTILGNIGAALIGGPGLVAGANFGRDYAVFE 281

Query: 297 P-CHGSAPDIAGKGIANP 313
           P       DI G+ +ANP
Sbjct: 282 PGSRHVGLDIKGQNVANP 299

>Suva_3.3 Chr3 (1464..2558) [1095 bp, 364 aa] {ON} YCL018W (REAL)
          Length = 364

 Score =  136 bits (343), Expect = 4e-36,   Method: Compositional matrix adjust.
 Identities = 123/364 (33%), Positives = 184/364 (50%), Gaps = 37/364 (10%)

Query: 26  IGLIPGDGIGKEVIPAGKQVLENLNS-KHGLSFNFIDLYAGFQTFQETGKALPDETVNVL 84
           I ++PGD +G+E+     +VL+ ++  +  + F+F     G      TG  L DE +   
Sbjct: 7   IVVLPGDHVGQEITEEAIKVLKAISEVRPNVKFDFEYHLIGGAAIDATGVPLTDEALEAS 66

Query: 85  KKQCQGALFGAVQSPTTKVEGYSSP---IVALRREMGLFANVRPVKS-----VEGSRNKP 136
           KK     L GAV  P     G   P   ++ +R+E+ L+AN+RP        +E S  KP
Sbjct: 67  KK-ADAVLLGAVGGPKWGT-GSVRPEQGLLKIRKELQLYANLRPCNFASESLLELSPIKP 124

Query: 137 -----IDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALK 191
                 D V+VRE    +Y    K    +  G  VA  +++ +    +RI  +A   A  
Sbjct: 125 QFARGTDFVVVRELVGGIYFGKRK----EDDGDGVAWDSEQYTVPEVQRITRMA---AFM 177

Query: 192 RLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFR 251
            LQ +    +    K+NVL+ +  L+R   K V E+ K+++  +K   Q++DS    L +
Sbjct: 178 ALQHQPPLPIWSLDKANVLASSR-LWR---KTVEETIKNEFPTLKVQHQLIDSAAMILVK 233

Query: 252 EP-QCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVG--PE----IVIGEPCHGSAPD 304
            P Q   +I+  N++GDI+SD A+ + GSLG++PSA++   P+      + EPCHGSAPD
Sbjct: 234 NPTQLNGIIITSNMFGDIISDEASCIPGSLGLLPSASLASLPDKNTAFGLYEPCHGSAPD 293

Query: 305 IAGKGIANPIATIRSTALMLEF-LGHNGAAQDIYKAVDANLREGAITTPDLGGKASTQQV 363
           +  K   NPIATI S A+ML+  L      Q I  AV   L  G I T DLGG  ST +V
Sbjct: 294 LP-KNKVNPIATILSAAMMLKLSLNMTAEGQAIEDAVKKVLDAG-IRTGDLGGSNSTIEV 351

Query: 364 VDDV 367
            D V
Sbjct: 352 GDAV 355

>CAGL0H03795g Chr8 (356535..357632) [1098 bp, 365 aa] {ON}
          Length = 365

 Score =  135 bits (341), Expect = 6e-36,   Method: Compositional matrix adjust.
 Identities = 122/366 (33%), Positives = 183/366 (50%), Gaps = 38/366 (10%)

Query: 25  TIGLIPGDGIGKEVIPAGKQVLENLNS--KHGLSFNFIDLYAGFQTFQETGKALPDETVN 82
           TI ++PGD +G+E+     +VL  +       ++F F     G      TG  LPDE + 
Sbjct: 6   TIVVLPGDHVGQEITEEAIKVLNAIQECRPDKVNFKFDHHLIGGAAIDATGVPLPDEALE 65

Query: 83  VLKKQCQGALFGAVQSPTTKVEGYSSP---IVALRREMGLFANVRPVKS-----VEGSRN 134
             KK     L GAV  P     G   P   ++ +R+E+ L+AN+RP        ++ S  
Sbjct: 66  ASKK-ADAVLLGAVGGPKWGT-GAVRPEQGLLKIRKELQLYANLRPCNFASDSLLDLSPL 123

Query: 135 KP-----IDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIA 189
           KP      D V+VRE    +Y    K    +  G  VA  +++ S    +RI  +A   A
Sbjct: 124 KPEIARGTDFVVVRELVGGIYFGERK----EDEGDGVAWDSEKYSVPEVQRITRMA---A 176

Query: 190 LKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRL 249
              LQ      +    K+NVL+ +  L+R   K V E+ K+++ Q+    Q++DS    L
Sbjct: 177 FMALQHNPPLPIWSLDKANVLASSR-LWR---KTVEETIKNEFPQLTVQHQLIDSAAMIL 232

Query: 250 FREPQCFD-VIVAPNLYGDILSDGAAALVGSLGVVPSANVG--PE----IVIGEPCHGSA 302
            + P   + +I+  N++GDI+SD A+ + GSLG++PSA++   P+      + EPCHGSA
Sbjct: 233 VKNPTHLNGIIITNNMFGDIISDEASVIPGSLGLLPSASLASLPDKNTAFGLYEPCHGSA 292

Query: 303 PDIAGKGIANPIATIRSTALMLEF-LGHNGAAQDIYKAVDANLREGAITTPDLGGKASTQ 361
           PD+  KG  NP+ATI S A+ML+  L      + I +AV   L  G I T DL G  ST 
Sbjct: 293 PDLP-KGKVNPVATILSAAMMLKLSLDLFEEGEIIEQAVKKVLDSG-IRTADLKGTNSTT 350

Query: 362 QVVDDV 367
           +V D V
Sbjct: 351 EVGDAV 356

>KNAG0I01280 Chr9 complement(245603..246946) [1344 bp, 447 aa] {ON}
           Anc_1.402 YCL018W
          Length = 447

 Score =  136 bits (343), Expect = 1e-35,   Method: Compositional matrix adjust.
 Identities = 122/373 (32%), Positives = 189/373 (50%), Gaps = 37/373 (9%)

Query: 17  TNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNS-KHGLSFNFIDLYAGFQTFQETGKA 75
           T  A+ +  I ++PGD +G+E+     +VL  ++S +  ++F+F     G      TG  
Sbjct: 81  TAMAQTTKHIVVLPGDHVGQEITEEAIKVLNAISSVRPNVNFDFQHHLIGGAAIDATGVP 140

Query: 76  LPDETVNVLKKQCQGALFGAVQSPTTKVEGYSSP---IVALRREMGLFANVRPVKS---- 128
           LPDE +   KK     L GAV  P     G   P   ++ +R+E+ L+AN+RP       
Sbjct: 141 LPDEALEASKK-ADAVLLGAVGGPKWGT-GSVRPEQGLLKIRKELQLYANLRPCNFASDS 198

Query: 129 -VEGSRNKP-----IDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIA 182
            ++ S  KP      D+ IVRE    +Y    K   D+  G         +SE+  +RI 
Sbjct: 199 LLDLSPLKPEIVKGTDICIVRELVGGIYFGERKE--DEGDGVAWDSEKYSVSEV--QRIT 254

Query: 183 TIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIV 242
            +A  +AL   Q      +    K+NVL+ +  L+R   K V E+ K+++  +    Q++
Sbjct: 255 RMAGFLAL---QHNPPLPVWSLDKANVLASSR-LWR---KTVEETIKNEFPTLTVQHQLI 307

Query: 243 DSMVYRLFREPQCFD-VIVAPNLYGDILSDGAAALVGSLGVVPSANVG--PE----IVIG 295
           DS    L + P   + V++A N++GDI+SD A+ + GSLG++PSA++   P+      + 
Sbjct: 308 DSAAMILVKNPTHLNGVVIANNMFGDIISDEASVIPGSLGLLPSASLASLPDTNTAFGLY 367

Query: 296 EPCHGSAPDIAGKGIANPIATIRSTALMLEF-LGHNGAAQDIYKAVDANLREGAITTPDL 354
           EPCHGSAPD+  KG  NP+ATI S A+ML+  L        + KAV   L  G + T DL
Sbjct: 368 EPCHGSAPDLP-KGKVNPVATILSVAMMLKLSLNMTEEGIAVEKAVKQVLDSG-VRTADL 425

Query: 355 GGKASTQQVVDDV 367
            G  ST +V D +
Sbjct: 426 RGSNSTSEVGDAI 438

>ZYRO0E04796g Chr5 (362881..363969) [1089 bp, 362 aa] {ON}
           uniprot|Q96WI0 Zygosaccharomyces rouxii LEU2 3-
           isopropylmalate dehydrogenase
          Length = 362

 Score =  134 bits (338), Expect = 1e-35,   Method: Compositional matrix adjust.
 Identities = 121/367 (32%), Positives = 186/367 (50%), Gaps = 37/367 (10%)

Query: 23  SLTIGLIPGDGIGKEVIPAGKQVLENLNS-KHGLSFNFIDLYAGFQTFQETGKALPDETV 81
           S  I ++PGD  G+E+     +VLE ++       FNF     G      TG  LPD+ +
Sbjct: 2   SKNIVVLPGDHAGQEIAQEAIKVLEAISEVSPEAKFNFQHHLIGGAAIDATGSPLPDDAL 61

Query: 82  NVLKKQCQGALFGAVQSPTTKVEGYSSP---IVALRREMGLFANVRP----------VKS 128
              KK     L GAV  P     G   P   ++ +R+E+ L+AN+RP          +  
Sbjct: 62  AAAKKADA-VLLGAVGGPKWGT-GSVRPEQGLLKIRKELQLYANLRPCNFASESLLDLSP 119

Query: 129 VEGSRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDI 188
           ++    K  D V+VRE    +Y    K    +  G  VA  +++ ++   +R+  +A   
Sbjct: 120 LKPQHAKGTDFVVVRELVGGIYFGERK----EDEGDGVAWDSEKYTKPEVQRLTRMA--- 172

Query: 189 ALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYR 248
           A   LQ      +    K+NVL+ +  L+R   K V E+ K+++ Q+K N Q++DS    
Sbjct: 173 AFLALQHNPPLPIWSLDKANVLASSR-LWR---KTVEETIKNEFPQLKLNHQLIDSAAMI 228

Query: 249 LFREP-QCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVG--PE----IVIGEPCHGS 301
           L + P Q   +++  NL+GDI+SD A+ + GSLG++PSA++   P+      + EPCHGS
Sbjct: 229 LVKSPTQLNGIVLTSNLFGDIISDEASVIPGSLGLLPSASLASLPDTNEAFGLYEPCHGS 288

Query: 302 APDIAGKGIANPIATIRSTALMLEF-LGHNGAAQDIYKAVDANLREGAITTPDLGGKAST 360
           APD+  KG  NPIA I S A+ML+  L  +   + + KAV   L  G + T DLGG  ST
Sbjct: 289 APDLP-KGKVNPIAMILSAAMMLKLSLNLSKEGEAVEKAVKQVLDSG-VRTGDLGGSNST 346

Query: 361 QQVVDDV 367
            +V D +
Sbjct: 347 SEVGDAI 353

>Kwal_0.225 s0 (111017..112111) [1095 bp, 364 aa] {ON} YCL018W
           (LEU2) - beta-IPM (isopropylmalate) dehydrogenase
           [contig 82] FULL
          Length = 364

 Score =  134 bits (336), Expect = 3e-35,   Method: Compositional matrix adjust.
 Identities = 121/372 (32%), Positives = 190/372 (51%), Gaps = 45/372 (12%)

Query: 26  IGLIPGDGIGKEVIPAGKQVLENLNS-KHGLSFNFIDLYAGFQTFQETGKALPDETVNVL 84
           I ++PGD +G+E+     +VL+ ++  +    F F     G      TG+ LPD ++   
Sbjct: 7   IVVLPGDHVGQEITEEAVKVLKAISEVRPEKQFEFQYHLIGGAAIDATGEPLPDASLEAA 66

Query: 85  KKQCQGALFGAVQSPTTKVEGYSSP---IVALRREMGLFANVRPVKS-----VEGSRNKP 136
           KK     L GAV  P     G   P   ++ +R+E+ L+AN+RP        ++ S  KP
Sbjct: 67  KK-SDAVLLGAVGGPKWGT-GAVRPEQGLLKIRKELQLYANLRPCNFASESLLDLSPLKP 124

Query: 137 -----IDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALK 191
                 D V+VRE    +Y    K    + TG  VA  +++ S    +RI  +A   A  
Sbjct: 125 ECARGTDFVVVRELVGGIYFGERK----EDTGDGVAWDSEQYSVPEVQRITRMA---AFL 177

Query: 192 RLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFR 251
            LQ      +    K+NVL+ +  L+R   K V E+ K+++  +    Q++DS    L +
Sbjct: 178 ALQHSPPLPVWSLDKANVLASSR-LWR---KTVEETIKNEFPTLTVQHQLIDSAAMILVK 233

Query: 252 EP-QCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVG--PE----IVIGEPCHGSAPD 304
            P Q   VI+  N++GDI+SD A+ + GSLG++PSA++   P+      + EPCHGSAPD
Sbjct: 234 NPTQLNGVIITNNMFGDIISDEASVIPGSLGLLPSASLASLPDSNTAFGLYEPCHGSAPD 293

Query: 305 IAGKGIANPIATIRSTALMLEF---LGHNGAA--QDIYKAVDANLREGAITTPDLGGKAS 359
           +  KG  NPIATI S A+ML+    +   GAA  + + K +D+ +R     T DL G ++
Sbjct: 294 LP-KGKVNPIATILSAAMMLKLSLDMFEEGAAVEEAVRKVLDSGVR-----TADLKGTST 347

Query: 360 TQQVVDDVLSRL 371
           T +V + V+  L
Sbjct: 348 TSEVGEAVVKAL 359

>KAFR0I02200 Chr9 (449737..450834) [1098 bp, 365 aa] {ON} Anc_1.402
           YCL018W
          Length = 365

 Score =  128 bits (322), Expect = 3e-33,   Method: Compositional matrix adjust.
 Identities = 116/364 (31%), Positives = 181/364 (49%), Gaps = 45/364 (12%)

Query: 26  IGLIPGDGIGKEVIPAGKQVLENLNS-KHGLSFNFIDLYAGFQTFQETGKALPDETVNVL 84
           I + PGD IG E++    +VL+ +      +SF +     G      TG+ L DE + V 
Sbjct: 7   ITVFPGDHIGTEIVRETVKVLDAIAEVSPNVSFKYNYQLIGGAAIDATGEPLTDEALQV- 65

Query: 85  KKQCQGALFGAVQSPTTKVEGYSSP---IVALRREMGLFANVRPVKSVEGS--RNKPI-- 137
            K     L GAV  P     G   P   ++ +R+E+G++AN+RP + V  +     P+  
Sbjct: 66  AKNSDAILLGAVGGPKWG-HGLVRPEQGLLKIRKELGVYANLRPCQFVSETLLDLSPLKR 124

Query: 138 ------DMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALK 191
                 D VIVRE    +Y    +   D   G      +  + EI  +RI  +A   A  
Sbjct: 125 EIVQGTDFVIVRELVGGIYFGERQEAGDD--GVAWDKESYSVPEI--QRITRMA---AFL 177

Query: 192 RLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFR 251
            LQ      +    K+NVL+ T  L+R   K V E+ K+++  +  N  ++DS    L +
Sbjct: 178 ALQHNPPLPVWSLDKANVLA-TSRLWR---KTVEETIKNEFPTLTINHHLIDSAAMTLVQ 233

Query: 252 EPQCFD-VIVAPNLYGDILSDGAAALVGSLGVVPSANVG--PE----IVIGEPCHGSAPD 304
            P   + V++  N++GDI+SD A+ + GSLG++PSA++   P+    + + EPCHGSAPD
Sbjct: 234 NPTKLNGVVITTNMFGDIISDEASVIPGSLGLLPSASLASLPDKNDALGLYEPCHGSAPD 293

Query: 305 IAGKGIANPIATIRSTALMLEF---LGHNGAA--QDIYKAVDANLREGAITTPDLGGKAS 359
           +     ANPIATI S A+M +    L   G A  + + + +DA ++ G     DLGGK +
Sbjct: 294 LPADH-ANPIATILSAAMMCKLSLNLTKEGNAIEEAVKRTIDAGIKTG-----DLGGKNT 347

Query: 360 TQQV 363
           T +V
Sbjct: 348 TTEV 351

>NCAS0C04870 Chr3 complement(993177..994274) [1098 bp, 365 aa] {ON}
           Anc_1.402
          Length = 365

 Score =  126 bits (316), Expect = 2e-32,   Method: Compositional matrix adjust.
 Identities = 114/369 (30%), Positives = 179/369 (48%), Gaps = 46/369 (12%)

Query: 26  IGLIPGDGIGKEVIPAGKQVLENLN--SKHGLSFNFIDLYAGFQTFQETGKALPDETVNV 83
           I ++PGD +G E+     +VL+ +       + F+F     G       G  L DE +  
Sbjct: 7   IVVLPGDHVGGEITEEAIKVLKAIEQVESSKVKFDFQYHLIGGAAIDAAGVPLTDEALEA 66

Query: 84  LKKQCQGALFGAVQSPTTKVEGYSSP---IVALRREMGLFANVRP----------VKSVE 130
            KK     L GAV  P     G   P   ++ +R+E+GL+AN+RP          +  + 
Sbjct: 67  SKK-ADAVLLGAVGGPKWGT-GAVRPEQGLLKIRKELGLYANLRPCNFASEPLLGLSPLR 124

Query: 131 GSRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIAL 190
               K  D ++VRE    +Y    K    +  G  VA  +++ S     RI  +A   A 
Sbjct: 125 PEIAKGTDFMVVRELVGGIYFGERK----EDDGDGVAWDSEKYSVPEVERITRMA---AF 177

Query: 191 KRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLF 250
             LQ      +    K+NVL+ +  L+R   K V  + K+++  +    Q++DS    L 
Sbjct: 178 LALQHNPPLPIWSLDKANVLASSR-LWR---KTVEATIKNEFPTLTVQNQLIDSAAMILV 233

Query: 251 REP-QCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVG--PE----IVIGEPCHGSAP 303
           + P Q   +I+  N++GDI+SD A+ + GSLG++PSA++   P+      + EPCHGSAP
Sbjct: 234 KNPTQLNGIIITSNMFGDIISDEASVIPGSLGLLPSASLASLPDSNTAFGLYEPCHGSAP 293

Query: 304 DIAGKGIANPIATIRSTALMLEF---LGHNGAA--QDIYKAVDANLREGAITTPDLGGKA 358
           D+  K   NP+ATI S A+ML+    +   G A  + + + +DA +R G     DLGG  
Sbjct: 294 DLP-KNKVNPVATILSAAMMLKLSLNMVKEGEAVEEAVRRVLDAGVRTG-----DLGGSN 347

Query: 359 STQQVVDDV 367
           STQ+V D +
Sbjct: 348 STQEVGDAI 356

>SAKL0D08690g Chr4 complement(723302..724396) [1095 bp, 364 aa] {ON}
           highly similar to uniprot|P04173 Saccharomyces
           cerevisiae YCL018W LEU2 Beta-isopropylmalate
           dehydrogenase catalyzes the third step in the leucine
           biosynthesis pathway
          Length = 364

 Score =  125 bits (315), Expect = 3e-32,   Method: Compositional matrix adjust.
 Identities = 113/369 (30%), Positives = 186/369 (50%), Gaps = 45/369 (12%)

Query: 26  IGLIPGDGIGKEVIPAGKQVLENLNS-KHGLSFNFIDLYAGFQTFQETGKALPDETVNVL 84
           I ++PGD +G+E+     +VL+ ++  +  + F++     G      TG  LPDE ++  
Sbjct: 7   IVVLPGDHVGQEITAEAIRVLDAISEVRPDVKFDYQYHLIGGAAIDATGVPLPDEALDAA 66

Query: 85  KKQCQGALFGAVQSPTTKVEGYSSP---IVALRREMGLFANVRP----------VKSVEG 131
           KK     L GAV  P     G   P   ++ +R+E+ L+AN+RP          +  ++ 
Sbjct: 67  KKADA-VLLGAVGGPKWGT-GQVRPEQGLLKIRKELQLYANLRPCNFASDSLLDLSPLKP 124

Query: 132 SRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALK 191
              K  D V+VRE    +Y    K    +  G  VA  +++ S    +RI  +A   A  
Sbjct: 125 EYAKGTDFVVVRELVGGIYFGERK----EDEGDGVAWDSEKYSVPEVQRITRMA---AFL 177

Query: 192 RLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFR 251
            LQ      +    K+NVL+ +  L+R   K V E+ K+++  +    Q++DS    L +
Sbjct: 178 ALQQNPPLPIWSLDKANVLASSR-LWR---KTVEETIKNEFPTLTVQHQLIDSAAMILVK 233

Query: 252 EPQCFD-VIVAPNLYGDILSDGAAALVGSLGVVPSANVG--PE----IVIGEPCHGSAPD 304
            P   + +++  N++GDI+SD A+ + GSLG++PSA++   P+      + EPCHGSAPD
Sbjct: 234 SPTKLNGIVITSNMFGDIISDEASVIPGSLGLLPSASLASLPDSNTAFGLYEPCHGSAPD 293

Query: 305 IAGKGIANPIATIRSTALMLEFLGH-----NGAAQDIYKAVDANLREGAITTPDLGGKAS 359
           +  K   NPIATI S A+ML+   +     N   + + + +DA +R     T DL G+ S
Sbjct: 294 LP-KNKVNPIATILSAAMMLKLSLNLVEEGNAVEEAVRRVLDAGIR-----TADLRGENS 347

Query: 360 TQQVVDDVL 368
           T +V D V+
Sbjct: 348 TSEVGDAVV 356

>TPHA0B03730 Chr2 complement(878199..879296) [1098 bp, 365 aa] {ON}
           Anc_1.402 YCL018W
          Length = 365

 Score =  119 bits (298), Expect = 7e-30,   Method: Compositional matrix adjust.
 Identities = 113/372 (30%), Positives = 177/372 (47%), Gaps = 50/372 (13%)

Query: 25  TIGLIPGDGIGKEVIPAGKQVLENLNS--KHGLSFNFIDLYAGFQTFQETGKALPDETVN 82
            I ++PGD +G EV     ++L+ +     + + FNF     G      TG  LPDE++ 
Sbjct: 6   NIVVLPGDHVGGEVTEEAVKILKAIEEVRNNKVKFNFEYHLIGGAAIDATGNPLPDESLE 65

Query: 83  VLKKQCQGALFGAVQSPTTKVEGYSSP---IVALRREMGLFANVRP----------VKSV 129
              K+    L GAV  P     G   P   ++ +R+E+ L+AN+RP          +  +
Sbjct: 66  A-SKRADAVLLGAVGGPKWGT-GSVRPEQGLLKIRKELQLYANLRPCNFASDSLLDLSPL 123

Query: 130 EGSRNKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIA 189
           +    K  D  +VRE    +Y    K    +  G  VA  +++ S    +RI  +A   A
Sbjct: 124 KEKYAKGTDFTVVRELVGGIYFGKRK----EDDGDGVAWDSEQYSVPEVQRITRMA---A 176

Query: 190 LKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRL 249
              +Q      +    K+NVL+ +  L+R   K V E+ ++++  +K + Q++DS    L
Sbjct: 177 FLAMQHNPPLPIWSLDKANVLASSR-LWR---KTVEETIQNEFPSLKVSHQLIDSAAMIL 232

Query: 250 FREP-QCFDVIVAPNLYGDILSDGAAALVG--------SLGVVPSANVGPEIVIGEPCHG 300
            + P Q   +I+  N++GDI+SD A+ + G        SL  +P  N      + EPCHG
Sbjct: 233 VKNPTQLNGIIITNNMFGDIISDEASVIPGSLGLLPSASLSSLPDTNSA--FGLYEPCHG 290

Query: 301 SAPDIAGKGIANPIATIRSTALMLEF---LGHNGAA--QDIYKAVDANLREGAITTPDLG 355
           SAPD+  KG  NPI TI S A+ML+    L   G A  + + + +D N+R     T DLG
Sbjct: 291 SAPDLP-KGKVNPIGTILSVAMMLKLSLNLKEEGIAVEEAVRRVLDNNIR-----TADLG 344

Query: 356 GKASTQQVVDDV 367
           G  ST  + D V
Sbjct: 345 GSNSTSDIGDAV 356

>KAFR0H03160 Chr8 complement(602807..604072) [1266 bp, 421 aa] {ON}
           Anc_1.396 YLR174W
          Length = 421

 Score = 59.7 bits (143), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 43/127 (33%), Positives = 67/127 (52%), Gaps = 13/127 (10%)

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNK----DKYGQIK 236
            A  + ++ALKR     +  L  T K+ VL + DG F++I +E+YES+     D+ G I 
Sbjct: 195 FARASFEMALKR-----KMPLFFTTKNTVLKRYDGKFKDIFQEMYESDYKVQFDEIG-IL 248

Query: 237 YNEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVI 294
           Y  +++D MV ++ +    F +I   N  GD+ SD  A   GSLG++ S  V P+     
Sbjct: 249 YEHRLIDDMVAQMLKSTGGF-IIAMKNYDGDVQSDIVAQGFGSLGLMTSMLVAPDGKTFE 307

Query: 295 GEPCHGS 301
            E  HG+
Sbjct: 308 SEAAHGT 314

>Kwal_23.4210 s23 (619516..620784) [1269 bp, 422 aa] {ON} YDL066W
           (IDP1) - Mitochondrial form of NADP-specific isocitrate
           dehydrogenase [contig 1] FULL
          Length = 422

 Score = 58.2 bits (139), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 60/206 (29%), Positives = 95/206 (46%), Gaps = 20/206 (9%)

Query: 103 VEGYSSPIVALRREMGLFANVRPVKSVEGSRNKPIDMVIVRENTEDLYIKIEKTYIDKAT 162
           V G+  PI+     +G  A+    ++ +    K   + +V    +    KI + +  K T
Sbjct: 129 VPGWQKPII-----IGRHAHGDQYRATDAIIEKAGKLELVHRPADGSEPKILQVHEFKGT 183

Query: 163 GTR-VADATKRISEIATRRIATIALDIAL-KRLQTRGEATLTVTHKSNVLSQTDGLFREI 220
           G R VA A     E + R  A  +  +AL KRL       L ++ K+ +L Q DG F++I
Sbjct: 184 GARGVALAMYNTDE-SIRGFAHASFKLALSKRL------NLFMSTKNTILKQYDGRFKDI 236

Query: 221 CKEVYESNKDKYGQ---IKYNEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALV 277
            +EVY        +   I Y  +++D MV ++ +    F V+   N  GD+LSD  A   
Sbjct: 237 FQEVYAQEYQTQFRDEGISYEHRLIDDMVAQMIKSRGGF-VMALKNYDGDVLSDIVAQGF 295

Query: 278 GSLGVVPSANVGPE--IVIGEPCHGS 301
           GSLG++ S  V P+      E  HG+
Sbjct: 296 GSLGLMTSMLVTPDGKTFESEAAHGT 321

>Kpol_1055.78 s1055 (207889..209172) [1284 bp, 427 aa] {ON}
           (207889..209172) [1284 nt, 428 aa]
          Length = 427

 Score = 57.4 bits (137), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 59/209 (28%), Positives = 97/209 (46%), Gaps = 32/209 (15%)

Query: 192 RLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESN-KDKYGQ--IKYNEQIVDSMVYR 248
           +L    +  L ++ K+ +L + DG F++I +E+YES+ K ++    I Y  +++D MV +
Sbjct: 209 KLAINKKLNLFLSTKNTILKKYDGRFKDIFQEIYESDYKSQFENLGISYEHRLIDDMVAQ 268

Query: 249 LFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIGEPCHGSAP--- 303
           + +    F ++   N  GD+ SD  A   GSLG++ S  V P+      E  HG+     
Sbjct: 269 MIKSKGGF-IMALKNYDGDVQSDIVAQGFGSLGLMTSVLVTPDGKTFESEAAHGTVTRHY 327

Query: 304 ---DIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGA---------ITT 351
              +   +   N IA+I + +  L   G   +  D+ K   ANL E A         I T
Sbjct: 328 RQYEQGKETSTNSIASIFAWSRGLAKRGELDSTPDVIKF--ANLLESATLNTVQQDGIMT 385

Query: 352 PDLG---GKA------STQQVVDDVLSRL 371
            DL    GK       +T + +D V +RL
Sbjct: 386 KDLALACGKTERSAYVTTDEFLDAVATRL 414

>CAGL0H03663g Chr8 (337533..338789) [1257 bp, 418 aa] {ON} highly
           similar to uniprot|P41939 Saccharomyces cerevisiae
           YLR174w IDP2 isocitrate dehydrogenase or uniprot|P53982
           Saccharomyces cerevisiae YNL009w IDP3 or uniprot|P21954
           Saccharomyces cerevisiae YDL066w IDP1
          Length = 418

 Score = 56.2 bits (134), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 39/126 (30%), Positives = 67/126 (53%), Gaps = 11/126 (8%)

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVY-ESNKDKYGQ--IKY 237
            A  + ++A+KR     +  L  T K+ +L + DG F++I +++Y E  K K+ +  I Y
Sbjct: 193 FARASFELAIKR-----KLPLFFTTKNTILKKYDGRFKDIFQKMYDEDYKGKFKELGISY 247

Query: 238 NEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIG 295
             +++D MV ++ +    F +I   N  GD+ SD  A   GSLG++ S  + P+  I   
Sbjct: 248 EHRLIDDMVAQMIKSKGGF-IIAMKNYDGDVQSDIVAQGFGSLGLMTSTLLTPDGKIFES 306

Query: 296 EPCHGS 301
           E  HG+
Sbjct: 307 EAAHGT 312

>YDL066W Chr4 (334835..336121) [1287 bp, 428 aa] {ON}
           IDP1Mitochondrial NADP-specific isocitrate
           dehydrogenase, catalyzes the oxidation of isocitrate to
           alpha-ketoglutarate; not required for mitochondrial
           respiration and may function to divert
           alpha-ketoglutarate to biosynthetic processes
          Length = 428

 Score = 56.2 bits (134), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 36/106 (33%), Positives = 59/106 (55%), Gaps = 6/106 (5%)

Query: 201 LTVTHKSNVLSQTDGLFREICKEVYESN-KDKYGQ--IKYNEQIVDSMVYRLFREPQCFD 257
           L ++ K+ +L + DG F++I +EVYE+  K K+ Q  I Y  +++D MV ++ +    F 
Sbjct: 224 LFLSTKNTILKKYDGRFKDIFQEVYEAQYKSKFEQLGIHYEHRLIDDMVAQMIKSKGGF- 282

Query: 258 VIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIGEPCHGS 301
           ++   N  GD+ SD  A   GSLG++ S  V P+      E  HG+
Sbjct: 283 IMALKNYDGDVQSDIVAQGFGSLGLMTSILVTPDGKTFESEAAHGT 328

>CAGL0D00770g Chr4 (95715..96986) [1272 bp, 423 aa] {ON} highly
           similar to uniprot|P21954 Saccharomyces cerevisiae
           YDL066w IDP1 isocitrate dehydrogenase or uniprot|P41939
           Saccharomyces cerevisiae YLR174w IDP2 or uniprot|P53982
           Saccharomyces cerevisiae YNL009w IDP3
          Length = 423

 Score = 55.8 bits (133), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 35/115 (30%), Positives = 63/115 (54%), Gaps = 6/115 (5%)

Query: 192 RLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESN-KDKYGQ--IKYNEQIVDSMVYR 248
           +L  + +  L ++ K+ +L + DG F++I +EVY+S  K K+ +  I Y  +++D MV +
Sbjct: 210 KLALQKKLNLFLSTKNTILKKYDGRFKDIFQEVYDSEYKQKFAELNITYEHRLIDDMVAQ 269

Query: 249 LFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIGEPCHGS 301
           + +    F ++   N  GD+ SD  A   GSLG++ S  + P+      E  HG+
Sbjct: 270 MIKSKGGF-IMALKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKTFESEAAHGT 323

>TPHA0B02210 Chr2 (509945..511246) [1302 bp, 433 aa] {ON} Anc_4.254
           YDL066W
          Length = 433

 Score = 55.5 bits (132), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 51/173 (29%), Positives = 84/173 (48%), Gaps = 19/173 (10%)

Query: 201 LTVTHKSNVLSQTDGLFREICKEVYESN-KDKYG--QIKYNEQIVDSMVYRLFREPQCFD 257
           L ++ K+ +L + DG F+++ +EV++S  KDK+    IKY  +++D MV ++ +    + 
Sbjct: 229 LFLSTKNTILKKYDGRFKDVFQEVFDSTYKDKFEALNIKYEHRLIDDMVAQMIKSKGGY- 287

Query: 258 VIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIGEPCHGSAP-----DIAGKGI 310
           ++   N  GD+ SD  A   GSLG++ S  V P+      E  HG+          GK  
Sbjct: 288 IMALKNYDGDVQSDIVAQGFGSLGLMTSILVTPDGKTFESEAAHGTVTRHYRQHQQGKQT 347

Query: 311 A-NPIATIRSTALMLEFLGH-------NGAAQDIYKAVDANLREGAITTPDLG 355
           + N IA+I + +  L   G           AQ + KA    ++E  I T DL 
Sbjct: 348 STNSIASIFAWSRGLAKRGELDNTPDVMKFAQTLEKATLDTVQEDGIMTKDLA 400

>Skud_4.189 Chr4 (330300..331589) [1290 bp, 429 aa] {ON} YDL066W
           (REAL)
          Length = 429

 Score = 54.3 bits (129), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 36/115 (31%), Positives = 62/115 (53%), Gaps = 6/115 (5%)

Query: 192 RLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESN-KDKYGQ--IKYNEQIVDSMVYR 248
           +L    +  L ++ K+ +L + DG F++I +EVYE+  K K+ +  I Y  +++D MV +
Sbjct: 216 KLAIDKKLNLFLSTKNTILKKYDGRFKDIFQEVYEAEYKSKFEKLGIHYEHRLIDDMVAQ 275

Query: 249 LFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIGEPCHGS 301
           + +    F ++   N  GD+ SD  A   GSLG++ S  V P+      E  HG+
Sbjct: 276 MIKSKGGF-IMALKNYDGDVQSDIVAQGFGSLGLMTSILVTPDGKTFESEAAHGT 329

>NDAI0D04360 Chr4 (1024297..1025571) [1275 bp, 424 aa] {ON}
           Anc_4.254
          Length = 424

 Score = 54.3 bits (129), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 35/115 (30%), Positives = 62/115 (53%), Gaps = 6/115 (5%)

Query: 192 RLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESN-KDKYGQ--IKYNEQIVDSMVYR 248
           +L    +  L ++ K+ +L + DG F++I + +YE++ K K+ Q  I Y  +++D MV +
Sbjct: 215 KLAIDKKLNLFLSTKNTILKKYDGRFKDIFQSIYETHYKAKFQQLNINYEHRLIDDMVAQ 274

Query: 249 LFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIGEPCHGS 301
           + +    F ++   N  GD+ SD  A   GSLG++ S  V P+      E  HG+
Sbjct: 275 MIKSKGGF-IMALKNYDGDVQSDIVAQGFGSLGLMTSILVTPDGKTFESEAAHGT 328

>KNAG0H01670 Chr8 (298481..299755) [1275 bp, 424 aa] {ON} Anc_1.396
           YLR174W
          Length = 424

 Score = 54.3 bits (129), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 37/126 (29%), Positives = 68/126 (53%), Gaps = 11/126 (8%)

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESN-KDKYGQ--IKY 237
            A  + ++ALKR     +  L    K+ +L + DGLF++I +++Y+ + K K+ +  I +
Sbjct: 195 FAKSSFELALKR-----KLPLFFATKNTILKEYDGLFKDIFEKLYKDHYKTKFEELGITF 249

Query: 238 NEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIG 295
             +++D MV ++ +    F ++   N  GD+ SD  A   GSLG++ S  V P+  +   
Sbjct: 250 EHRLIDDMVAQMLKSNGGF-ILSLKNYDGDVQSDIVAQGFGSLGLMTSMLVTPDDSVFES 308

Query: 296 EPCHGS 301
           E  HG+
Sbjct: 309 EAAHGT 314

>SAKL0H02860g Chr8 (280944..282209) [1266 bp, 421 aa] {ON} highly
           similar to uniprot|P21954 Saccharomyces cerevisiae
           YDL066W IDP1 Mitochondrial NADP-specific isocitrate
           dehydrogenase catalyzes the oxidation of isocitrate to
           alpha-ketoglutarate not required for mitochondrial
           respiration and may function to divert alpha-
           ketoglutarate to biosynthetic processes
          Length = 421

 Score = 53.9 bits (128), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 53/206 (25%), Positives = 97/206 (47%), Gaps = 24/206 (11%)

Query: 103 VEGYSSPIVALRREMGLFANVRPVKSVEGSRNKP--IDMVIVRENTEDLYIKIEKTYIDK 160
           V G+  PI+     +G  A+    K+ +     P  +++V   EN  +   K+ + Y  K
Sbjct: 133 VPGWEKPII-----IGRHAHGDQYKATDAVIPGPGKLELVYKPENGPE---KVMEVYDYK 184

Query: 161 ATGTRVADATKRISEIATRRIATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREI 220
             G  +A      +E + R  A  +  +AL +     +  L ++ K+ +L + DG F++I
Sbjct: 185 GPGVALAMYN---TEESIRGFAHASFKLALTK-----KLNLYLSTKNTILKKYDGRFKDI 236

Query: 221 CKEVYESNKDKYGQ---IKYNEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALV 277
            +E+Y++   K  +   I Y  +++D MV ++ +    F ++   N  GD+ SD  A   
Sbjct: 237 FQELYDAEYKKQFEAAGIYYEHRLIDDMVAQMIKSKGGF-IMALKNYDGDVQSDIVAQGF 295

Query: 278 GSLGVVPSANVGPE--IVIGEPCHGS 301
           GSLG++ S  V P+      E  HG+
Sbjct: 296 GSLGLMTSVLVTPDGKTFESEAAHGT 321

>TBLA0C01290 Chr3 complement(283624..284880) [1257 bp, 418 aa] {ON}
           Anc_1.396 YLR174W
          Length = 418

 Score = 53.9 bits (128), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 39/126 (30%), Positives = 65/126 (51%), Gaps = 11/126 (8%)

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVY-ESNKDKYG--QIKY 237
            A  + + AL+R     +  L  T K+ +L Q DG F++I +E+Y +  +DK+    I Y
Sbjct: 198 FAKASFEFALER-----KIPLYSTTKNTILKQYDGKFKDIFEEMYAKEYEDKFKVLNIWY 252

Query: 238 NEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIG 295
             +++D MV ++ +    F +I   N  GD+ SD  A   GSLG++ S  + P+      
Sbjct: 253 EHRLIDDMVAQMLKSKGGF-IIAMKNYDGDVESDVVAQGFGSLGLMTSVLLTPDGSSFES 311

Query: 296 EPCHGS 301
           E  HG+
Sbjct: 312 EAAHGT 317

>ZYRO0E05016g Chr5 complement(379654..380889) [1236 bp, 411 aa] {ON}
           highly similar to uniprot|P41939 Saccharomyces
           cerevisiae YLR174W IDP2 Cytosolic NADP-specific
           isocitrate dehydrogenase catalyzes oxidation of
           isocitrate to alpha- ketoglutarate levels are elevated
           during growth on non- fermentable carbon sources and
           reduced during growth on glucose
          Length = 411

 Score = 53.5 bits (127), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 40/127 (31%), Positives = 65/127 (51%), Gaps = 13/127 (10%)

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYE----SNKDKYGQIK 236
            A  + ++AL+R Q      L  T K+ +L + DG F++I + +YE    S  +K G I 
Sbjct: 193 FAKASFELALERKQP-----LYSTTKNTILKKYDGKFKDIFEAMYEKEYRSQFEKLG-IW 246

Query: 237 YNEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVI 294
           Y  +++D MV ++ +    + +I   N  GD+ SD  A   GSLG++ S  V P+     
Sbjct: 247 YEHRLIDDMVAQMLKSKGGY-IIAMKNYDGDVQSDIVAQGFGSLGLMTSVLVTPDGKTFE 305

Query: 295 GEPCHGS 301
            E  HG+
Sbjct: 306 SEAAHGT 312

>Ecym_1306 Chr1 complement(619565..620812) [1248 bp, 415 aa] {ON}
           similar to Ashbya gossypii AAL022W
          Length = 415

 Score = 53.1 bits (126), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 39/126 (30%), Positives = 64/126 (50%), Gaps = 11/126 (8%)

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESN-KDKYGQ--IKY 237
            A  + ++AL+R     +  L  T K+ +L + DG F++I + +YE   K K+    I Y
Sbjct: 194 FAKSSFELALER-----KMPLYSTTKNTILKKYDGQFKDIFEGMYEREYKQKFEAVGIWY 248

Query: 238 NEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIG 295
             +++D MV ++ +    F +I   N  GD+ SD  A   GSLG++ S  V P+      
Sbjct: 249 EHRLIDDMVAQMLKSKGGF-IIAMKNYDGDVQSDIVAQGFGSLGLMTSVLVSPDGKTFES 307

Query: 296 EPCHGS 301
           E  HG+
Sbjct: 308 EAAHGT 313

>KAFR0I02130 Chr9 (438428..439654) [1227 bp, 408 aa] {ON} Anc_1.396
           YLR174W
          Length = 408

 Score = 52.8 bits (125), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 35/106 (33%), Positives = 56/106 (52%), Gaps = 6/106 (5%)

Query: 201 LTVTHKSNVLSQTDGLFREICKEVYESN-KDKYGQ--IKYNEQIVDSMVYRLFREPQCFD 257
           L  T K+ +L Q DG F++I K VYE+  K+ + +  I Y  +++D MV ++ +    F 
Sbjct: 205 LYSTTKNTILKQYDGQFKDIFKTVYENEYKETFEELGIWYEHRLIDDMVAQMLKSKGGF- 263

Query: 258 VIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIGEPCHGS 301
           +I   N  GD+ SD  A   GSLG++ S  +  +      E  HG+
Sbjct: 264 IIAMKNYDGDVQSDIVAQGFGSLGLMTSTLIAADGKTFESEAAHGT 309

>KNAG0I01320 Chr9 complement(255478..256716) [1239 bp, 412 aa] {ON}
           Anc_1.396 YLR174W
          Length = 412

 Score = 52.4 bits (124), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 33/106 (31%), Positives = 58/106 (54%), Gaps = 6/106 (5%)

Query: 201 LTVTHKSNVLSQTDGLFREICKEVYESN-KDKYGQ--IKYNEQIVDSMVYRLFREPQCFD 257
           L  T K+ +L + DG+F++I + +YE   K+K+ +  I Y  +++D MV ++ +    + 
Sbjct: 210 LYSTTKNTILKKYDGMFKDIFEGMYEREYKEKFEELGIWYEHRLIDDMVAQMLKSSGGY- 268

Query: 258 VIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIGEPCHGS 301
           +I   N  GD+ SD  A   GSLG++ S  + P+      E  HG+
Sbjct: 269 IIAMKNYDGDVQSDIVAQGFGSLGLMTSVLITPDGKTFESEAAHGT 314

>KLTH0H12012g Chr8 (1026586..1027827) [1242 bp, 413 aa] {ON} highly
           similar to uniprot|P41939 Saccharomyces cerevisiae
           YLR174W IDP2 Cytosolic NADP-specific isocitrate
           dehydrogenase catalyzes oxidation of isocitrate to
           alpha- ketoglutarate levels are elevated during growth
           on non- fermentable carbon sources and reduced during
           growth on glucose
          Length = 413

 Score = 52.4 bits (124), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 60/220 (27%), Positives = 98/220 (44%), Gaps = 33/220 (15%)

Query: 179 RRIATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESN-KDKYGQ--I 235
           R  A  + ++AL+R     +  L  T K+ +L + DG F++  + +YE+  ++++ +  I
Sbjct: 192 RGFARASFELALQR-----KMPLYSTTKNTILKRYDGRFKDEFEAMYEAEYRERFERAGI 246

Query: 236 KYNEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IV 293
            Y  +++D MV ++ +    F VI   N  GD+ SD  A   GSLG++ S  V P+    
Sbjct: 247 WYEHRLIDDMVAQMLKSAGGF-VIAMKNYDGDVQSDIVAQGFGSLGLMTSVLVTPDGRAF 305

Query: 294 IGEPCHGSAP-----DIAGKGIA-NPIATIRSTALMLEFLGH-------NGAAQDIYKAV 340
             E  HG+          GK  + N IA+I +    L   G         G A+ +  A 
Sbjct: 306 ESEAAHGTVTRHFRLHQQGKETSTNSIASIFAWTRGLLQRGRLDGTPEVEGFARALETAT 365

Query: 341 DANLREGAITTPDL---------GGKASTQQVVDDVLSRL 371
            A + E  I T DL             +T+  +D V  RL
Sbjct: 366 VATVNEDGIMTKDLALMLGRTDRASYVTTEDFIDAVEQRL 405

>NCAS0G03620 Chr7 complement(675224..676480) [1257 bp, 418 aa] {ON}
           Anc_1.396
          Length = 418

 Score = 52.4 bits (124), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 34/106 (32%), Positives = 56/106 (52%), Gaps = 6/106 (5%)

Query: 201 LTVTHKSNVLSQTDGLFREICKEVY-ESNKDKYGQ--IKYNEQIVDSMVYRLFREPQCFD 257
           L  T K+ +L + DG F++I  E+Y    KD++ +  I Y  +++D MV ++ +    F 
Sbjct: 211 LYFTTKNTILKKYDGTFKDIFMEMYLNEYKDEFDKLGIFYEHRLIDDMVAQMLKSKGGF- 269

Query: 258 VIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIGEPCHGS 301
           +I   N  GD+ SD  A   GSLG++ S  + P+      E  HG+
Sbjct: 270 IIAMKNYDGDVQSDIVAQGFGSLGLMTSVLITPDGKTFQSEAAHGT 315

>KLLA0B03355g Chr2 (303444..304733) [1290 bp, 429 aa] {ON} highly
           similar to uniprot|P21954 Saccharomyces cerevisiae
           YDL066W IDP1 Mitochondrial NADP-specific isocitrate
           dehydrogenase catalyzes the oxidation of isocitrate to
           alpha-ketoglutarate not required for mitochondrial
           respiration and may function to divert alpha-
           ketoglutarate to biosynthetic processes
          Length = 429

 Score = 52.4 bits (124), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 54/204 (26%), Positives = 97/204 (47%), Gaps = 19/204 (9%)

Query: 103 VEGYSSPIVALRREMGLFANVRPVKSVEGSRNKPIDMVIVRENTEDLYIKIEKTYIDKAT 162
           V G+  PIV     +G  A+    K+ +     P  + +V + T+    K  + Y  K  
Sbjct: 140 VPGWEKPIV-----IGRHAHGDQYKATDLVVPGPGKLELVYKPTDGSETKTLEVYDYKGP 194

Query: 163 GTRVADATKRISEIATRRIATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICK 222
           G  +A A     E + R  A  +  +A+ +     +  L ++ K+ +L + DG F++I +
Sbjct: 195 G--IALAMYNTDE-SIRGFAHASFKLAITK-----KLNLYLSTKNTILKKYDGRFKDIFQ 246

Query: 223 EVYESN-KDKYGQ--IKYNEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGS 279
           E+Y+S  K ++ +  I Y  +++D MV ++ +    F ++   N  GD+ SD  A   GS
Sbjct: 247 EIYDSEYKSEFEKLGIWYEHRLIDDMVAQMIKSKGGF-ILAFKNYDGDVQSDIVAQGFGS 305

Query: 280 LGVVPSANVGPE--IVIGEPCHGS 301
           LG++ S  V P+      E  HG+
Sbjct: 306 LGLMTSVLVTPDGKAFESEAAHGT 329

>SAKL0D08426g Chr4 (705189..706424) [1236 bp, 411 aa] {ON} highly
           similar to uniprot|P41939 Saccharomyces cerevisiae
           YLR174W IDP2 Cytosolic NADP-specific isocitrate
           dehydrogenase catalyzes oxidation of isocitrate to
           alpha- ketoglutarate levels are elevated during growth
           on non- fermentable carbon sources and reduced during
           growth on glucose
          Length = 411

 Score = 52.0 bits (123), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 38/126 (30%), Positives = 66/126 (52%), Gaps = 11/126 (8%)

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESN-KDKYG--QIKY 237
            A  + ++AL+R     +  L  T K+ +L + DG F++I + +Y S+ +DK+    I Y
Sbjct: 192 FAKASFELALER-----KLPLYSTTKNTILKRYDGKFKDIFESMYASDYQDKFEVIGIWY 246

Query: 238 NEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIG 295
             +++D MV ++ +    + +I   N  GD+ SD  A   GSLG++ S  V P+      
Sbjct: 247 EHRLIDDMVAQMLKSKGGY-IIAMKNYDGDVESDIVAQGFGSLGLMSSVLVTPDGKTFES 305

Query: 296 EPCHGS 301
           E  HG+
Sbjct: 306 EAAHGT 311

>AER061C Chr5 complement(749709..750986) [1278 bp, 425 aa] {ON}
           Syntenic homolog of Saccharomyces cerevisiae YDL066W
           (IDP1)
          Length = 425

 Score = 52.0 bits (123), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 34/115 (29%), Positives = 62/115 (53%), Gaps = 6/115 (5%)

Query: 192 RLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESN-KDKYGQ--IKYNEQIVDSMVYR 248
           RL    +  L ++ K+ +L Q DG F+++ +E+Y++  K ++ +  I Y  +++D MV +
Sbjct: 215 RLALAKQLNLFLSTKNTILKQYDGRFKDVFEELYQAQYKAEFERLGIYYEHRLIDDMVAQ 274

Query: 249 LFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIGEPCHGS 301
           + +    F ++   N  GD+ SD  A   GSLG++ S  V P+      E  HG+
Sbjct: 275 MVKSKGGF-IMALKNYDGDVQSDIVAQGFGSLGLMTSVLVTPDGKTFESEAAHGT 328

>AAL022W Chr1 (302946..304193) [1248 bp, 415 aa] {ON} Syntenic
           homolog of Saccharomyces cerevisiae YLR174W (IDP2) and
           YNL009W (IDP3)
          Length = 415

 Score = 52.0 bits (123), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 38/126 (30%), Positives = 65/126 (51%), Gaps = 11/126 (8%)

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESN-KDKY--GQIKY 237
            A  + ++AL+R     +  L  T K+ +L + DG F++I + +Y +  K+K+    I Y
Sbjct: 194 FAKSSFELALQR-----KMPLYSTTKNTILKKYDGKFKDIFEGMYAAEYKEKFEAAGIWY 248

Query: 238 NEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIG 295
             +++D MV ++ +    F +I   N  GD+ SD  A   GSLG++ S  V P+      
Sbjct: 249 EHRLIDDMVAQMLKSKGGF-IIAMKNYDGDVQSDIVAQGFGSLGLMTSVLVSPDGKTFES 307

Query: 296 EPCHGS 301
           E  HG+
Sbjct: 308 EAAHGT 313

>Smik_4.169 Chr4 (311244..312530) [1287 bp, 428 aa] {ON} YDL066W
           (REAL)
          Length = 428

 Score = 52.0 bits (123), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 34/106 (32%), Positives = 58/106 (54%), Gaps = 6/106 (5%)

Query: 201 LTVTHKSNVLSQTDGLFREICKEVYESN-KDKYGQ--IKYNEQIVDSMVYRLFREPQCFD 257
           L ++ K+ +L + DG F++I ++VYE+  K K+    I Y  +++D MV ++ +    F 
Sbjct: 224 LFLSTKNTILKKYDGRFKDIFQKVYEAQYKSKFEALGIHYEHRLIDDMVAQMIKSKGGF- 282

Query: 258 VIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIGEPCHGS 301
           ++   N  GD+ SD  A   GSLG++ S  V P+      E  HG+
Sbjct: 283 IMALKNYDGDVQSDIVAQGFGSLGLMTSILVTPDGKTFESEAAHGT 328

>KAFR0G03260 Chr7 complement(675642..676907) [1266 bp, 421 aa] {ON}
           Anc_4.254 YDL066W
          Length = 421

 Score = 51.6 bits (122), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 52/198 (26%), Positives = 90/198 (45%), Gaps = 28/198 (14%)

Query: 201 LTVTHKSNVLSQTDGLFREICKEVYESN-KDKYGQ--IKYNEQIVDSMVYRLFREPQCFD 257
           L +  K+ +L + DG F++I +++Y    K K+ Q  I Y  +++D MV ++ +    F 
Sbjct: 219 LFLATKNTILKKYDGRFKDIFQQIYNGQYKAKFEQLGITYEHRLIDDMVAQMIKSKGGF- 277

Query: 258 VIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIGEPCHGSAP------DIAGKG 309
           ++   N  GD+ SD  A   GSLG++ S  V P+      E  HG+         +  + 
Sbjct: 278 IMALKNYDGDVQSDIVAQGFGSLGLMTSILVSPDGKTFESEAAHGTVTRHFRRHQMGEET 337

Query: 310 IANPIATIRSTALMLEFLGHNGAAQDIYKAVDA-------NLREGAITTPDLG---GK-- 357
             N IA+I + +  L   G     +D+    +        +++E  I T DL    GK  
Sbjct: 338 STNSIASIFAWSRGLAKRGELDGTKDVIAFANKLEAATLDSVQEDGIMTKDLALASGKNN 397

Query: 358 ----ASTQQVVDDVLSRL 371
                +T + +D V +RL
Sbjct: 398 RSDYVNTDEFIDAVEARL 415

>YNL009W Chr14 (614821..616083) [1263 bp, 420 aa] {ON}
           IDP3Peroxisomal NADP-dependent isocitrate dehydrogenase,
           catalyzes oxidation of isocitrate to alpha-ketoglutarate
           with the formation of NADP(H+), required for growth on
           unsaturated fatty acids
          Length = 420

 Score = 51.6 bits (122), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 57/220 (25%), Positives = 95/220 (43%), Gaps = 37/220 (16%)

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESN-KDKYGQIK--Y 237
            A  + ++ALKR     +  L  T K+ +L   D  F++I   +++   K+K+  +K  Y
Sbjct: 192 FAKASFELALKR-----KLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQALKITY 246

Query: 238 NEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIG 295
             +++D MV ++ +    F +I   N  GD+ SD  A   GSLG++ S  + P+      
Sbjct: 247 EHRLIDDMVAQMLKSKGGF-IIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKTFES 305

Query: 296 EPCHGSAPDIAGKG------IANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLREGA- 348
           E  HG+      K         N IA+I +    +   G      D+ K    NL E A 
Sbjct: 306 EAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKF--GNLLEKAT 363

Query: 349 ITTPDLGGK-----------------ASTQQVVDDVLSRL 371
           + T  +GGK                  +T++ +D+V  RL
Sbjct: 364 LDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRL 403

>NCAS0A08720 Chr1 complement(1722511..1723752) [1242 bp, 413 aa]
           {ON} Anc_1.396
          Length = 413

 Score = 51.2 bits (121), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 38/129 (29%), Positives = 63/129 (48%), Gaps = 17/129 (13%)

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQ------ 234
            A  +  +AL+R     +  L  T K+ +L + DG F+ + +++YE    +Y Q      
Sbjct: 194 FARSSFQLALER-----QLPLYSTTKNTILKKYDGKFKSVFEDMYER---EYKQQFEDLG 245

Query: 235 IKYNEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--I 292
           I Y  +++D MV ++ +    F +I   N  GD+ SD  A   GSLG++ S  V P+   
Sbjct: 246 IWYEHRLIDDMVAQMLKSKGGF-IIAMKNYDGDVQSDIVAQGFGSLGLMTSVLVAPDGKT 304

Query: 293 VIGEPCHGS 301
              E  HG+
Sbjct: 305 FESEAAHGT 313

>CAGL0B04917g Chr2 complement(477939..479174) [1236 bp, 411 aa] {ON}
           highly similar to uniprot|P41939 Saccharomyces
           cerevisiae YLR174w IDP2 isocitrate dehydrogenase or
           uniprot|P53982 Saccharomyces cerevisiae YNL009w IDP3 or
           uniprot|P21954 Saccharomyces cerevisiae YDL066w IDP1
          Length = 411

 Score = 51.2 bits (121), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 37/130 (28%), Positives = 66/130 (50%), Gaps = 11/130 (8%)

Query: 177 ATRRIATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESN-KDKYGQ- 234
           + R  A  + ++AL+      E  L  T K+ +L + DG F++  + +YE+  K+++   
Sbjct: 188 SIRGFARASFNMALEH-----EMPLYSTTKNTILKKYDGKFKDTFESMYEAEYKEQFEAK 242

Query: 235 -IKYNEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE-- 291
            I Y  +++D MV ++ +    F +I   N  GD+ SD  A   GSLG++ S  + P+  
Sbjct: 243 GIWYEHRLIDDMVAQMLKSKGGF-IIAMKNYDGDVESDIVAQGFGSLGLMTSVLISPDGK 301

Query: 292 IVIGEPCHGS 301
               E  HG+
Sbjct: 302 TFESEAAHGT 311

>Suva_4.184 Chr4 (324382..325671) [1290 bp, 429 aa] {ON} YDL066W
           (REAL)
          Length = 429

 Score = 51.2 bits (121), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 33/106 (31%), Positives = 58/106 (54%), Gaps = 6/106 (5%)

Query: 201 LTVTHKSNVLSQTDGLFREICKEVYESN-KDKYGQ--IKYNEQIVDSMVYRLFREPQCFD 257
           L ++ K+ +L + DG F++I + +YE+  K K+ +  I Y  +++D MV ++ +    F 
Sbjct: 225 LFLSTKNTILKKYDGRFKDIFQNIYEAQYKPKFEELGIHYEHRLIDDMVAQMVKSKGGF- 283

Query: 258 VIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIGEPCHGS 301
           ++   N  GD+ SD  A   GSLG++ S  V P+      E  HG+
Sbjct: 284 IMALKNYDGDVQSDIVAQGFGSLGLMTSILVTPDGKTFESEAAHGT 329

>Smik_14.319 Chr14 (573167..574423) [1257 bp, 418 aa] {ON} YLR174W
           (REAL)
          Length = 418

 Score = 51.2 bits (121), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 38/126 (30%), Positives = 63/126 (50%), Gaps = 11/126 (8%)

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVY-ESNKDKYGQ--IKY 237
            A  + ++ALKR     +  L  T K+ +L   D  F++I   ++ E  ++K+    IKY
Sbjct: 192 FAKASFELALKR-----KLPLFFTTKNTILKNYDNQFKQIFDGLFNEKYREKFQALGIKY 246

Query: 238 NEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIG 295
             +++D MV ++ +    F +I   N  GD+ SD  A   GSLG++ S  V P+      
Sbjct: 247 EHRLIDDMVAQMLKSKGGF-IIAMKNYDGDVQSDIVAQGFGSLGLMTSILVTPDGKTFES 305

Query: 296 EPCHGS 301
           E  HG+
Sbjct: 306 EAAHGT 311

>KLTH0D14476g Chr4 complement(1184813..1186075) [1263 bp, 420 aa]
           {ON} highly similar to uniprot|P21954 Saccharomyces
           cerevisiae YDL066W IDP1 Mitochondrial NADP-specific
           isocitrate dehydrogenase catalyzes the oxidation of
           isocitrate to alpha-ketoglutarate not required for
           mitochondrial respiration and may function to divert
           alpha- ketoglutarate to biosynthetic processes
          Length = 420

 Score = 51.2 bits (121), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 47/182 (25%), Positives = 80/182 (43%), Gaps = 19/182 (10%)

Query: 192 RLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQ---IKYNEQIVDSMVYR 248
           RL    +  L +  K+ +L Q DG F+++ +++Y++   +  +   I Y  +++D MV +
Sbjct: 207 RLALSKQLNLFLATKNTILKQYDGRFKDLFQQLYDAEYREAFERAGISYEHRLIDDMVAQ 266

Query: 249 LFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIGEPCHGS----- 301
           + +    F V+   N  GD+ SD  A   GSLG++ S  + P+      E  HG+     
Sbjct: 267 MIKSRGGF-VLALKNYDGDVQSDIVAQGFGSLGLMSSVLITPDGNAFESEAAHGTVTRHF 325

Query: 302 -----APDIAGKGIANPIATIRSTALMLEFLGHNGAAQDIYKAVDANLR---EGAITTPD 353
                  + +   IA+  A  R  A   +  G    A   +    A LR   + AI T D
Sbjct: 326 RLHQQGKETSTNSIASIFAWTRGLARRADLDGTPAVADFAHALEGATLRTVQDDAIMTKD 385

Query: 354 LG 355
           L 
Sbjct: 386 LA 387

>KNAG0D04410 Chr4 complement(799414..800700) [1287 bp, 428 aa] {ON}
           Anc_4.254 YDL066W
          Length = 428

 Score = 51.2 bits (121), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 36/128 (28%), Positives = 67/128 (52%), Gaps = 12/128 (9%)

Query: 201 LTVTHKSNVLSQTDGLFREICKEVYESN-KDKYGQ--IKYNEQIVDSMVYRLFREPQCFD 257
           L ++ K+ +L + DG F+++ +E++++  K ++ +  I+Y  +++D MV ++ +    F 
Sbjct: 224 LFLSTKNTILKRYDGRFKDLFQEIFDAEYKQQFEESGIQYQHRLIDDMVAQMIKSKGGF- 282

Query: 258 VIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIGEPCHGSAPDIAGK------G 309
           ++   N  GD+ SD  A   GSLG++ S  V P+      E  HG+      K       
Sbjct: 283 IMALKNYDGDVQSDIVAQGFGSLGLMTSVLVTPDGKTFESEAAHGTVTRHYRKYQRGEET 342

Query: 310 IANPIATI 317
             NPIA+I
Sbjct: 343 STNPIASI 350

>TDEL0B06100 Chr2 complement(1076365..1077609) [1245 bp, 414 aa]
           {ON} Anc_1.396 YLR174W
          Length = 414

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 37/127 (29%), Positives = 66/127 (51%), Gaps = 13/127 (10%)

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVY----ESNKDKYGQIK 236
            A  + ++AL+R     +  L  T K+ +L + DG F+++ +++Y    +S  ++ G I 
Sbjct: 191 FAKASFELALER-----KLPLYSTTKNTILKKYDGKFKDVFEQMYADQYQSRFEELG-IW 244

Query: 237 YNEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVI 294
           Y  +++D MV ++ +    F +I   N  GD+ SD  A   GSLG++ S  V P+     
Sbjct: 245 YEHRLIDDMVAQMLKSKGGF-IIAMKNYDGDVESDIVAQGFGSLGLMTSVLVTPDGKTFE 303

Query: 295 GEPCHGS 301
            E  HG+
Sbjct: 304 SEAAHGT 310

>Kpol_1048.70 s1048 complement(198298..199557) [1260 bp, 419 aa]
           {ON} complement(198298..199557) [1260 nt, 420 aa]
          Length = 419

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 34/106 (32%), Positives = 56/106 (52%), Gaps = 6/106 (5%)

Query: 201 LTVTHKSNVLSQTDGLFREICKEVYESN-KDKYGQ--IKYNEQIVDSMVYRLFREPQCFD 257
           L  T K+ +L + DG +++I  ++YE + KDK+    I Y  +++D MV ++ +    F 
Sbjct: 212 LYSTTKNTILKKYDGQYKDIFNDMYEKDYKDKFEAKGIWYEHRLIDDMVAQMLKSKGGF- 270

Query: 258 VIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIGEPCHGS 301
           VI   N  GD+ SD  A   GSLG++ S  +  +      E  HG+
Sbjct: 271 VIAMKNYDGDVQSDVVAQGFGSLGLMSSILISDDGKTFESEAAHGT 316

>TDEL0E01160 Chr5 (234217..235488) [1272 bp, 423 aa] {ON} Anc_4.254
           YDL066W
          Length = 423

 Score = 50.4 bits (119), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 32/115 (27%), Positives = 61/115 (53%), Gaps = 6/115 (5%)

Query: 192 RLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESN-KDKY--GQIKYNEQIVDSMVYR 248
           +L    +  L ++ K+ +L + DG F++I +E++++  K ++    I Y  +++D MV +
Sbjct: 210 KLALNKKLNLFLSTKNTILKKYDGRFKDIFQEIFDAEYKTQFEAANISYEHRLIDDMVAQ 269

Query: 249 LFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIGEPCHGS 301
           + +    F ++   N  GD+ SD  A   GSLG++ S  V P+      E  HG+
Sbjct: 270 MIKSKGGF-IMALKNYDGDVQSDIVAQGFGSLGLMTSVLVTPDGKTFESEAAHGT 323

>Smik_12.235 Chr12 (451719..452957) [1239 bp, 412 aa] {ON} YLR174W
           (REAL)
          Length = 412

 Score = 50.4 bits (119), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 59/218 (27%), Positives = 100/218 (45%), Gaps = 33/218 (15%)

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVY-ESNKDKYGQ--IKY 237
            A  + ++A++R     +  L  T K+ +L + DG F+++ + +Y ES K+K+    I Y
Sbjct: 192 FAKASFELAIER-----KLPLYSTTKNTILKKYDGKFKDVFEGMYAESYKEKFESLGIWY 246

Query: 238 NEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIG 295
             +++D MV ++ +    + +I   N  GD+ SD  A   GSLG++ S  + P+      
Sbjct: 247 EHRLIDDMVAQMLKSKGGY-IIAMKNYDGDVESDIVAQGFGSLGLMTSVLITPDGKTFES 305

Query: 296 EPCHGSA-----PDIAGKGIA-NPIATIRSTALMLEFLGHNGAAQDIYK-------AVDA 342
           E  HG+          GK  + N IA+I +    +   G      D+ K       A   
Sbjct: 306 EAAHGTVTRHFRQHQQGKETSTNSIASIFAWTRGIIQRGKLDNTPDVVKFGQILESATVN 365

Query: 343 NLREGAITTPDLG---GKA------STQQVVDDVLSRL 371
            ++E  I T DL    GK       +T++ +D V SRL
Sbjct: 366 TVQEDGIMTKDLALILGKTERSAYVTTEEFIDAVESRL 403

>NDAI0G00850 Chr7 (179074..180333) [1260 bp, 419 aa] {ON} Anc_1.396
          Length = 419

 Score = 50.4 bits (119), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 52/205 (25%), Positives = 94/205 (45%), Gaps = 17/205 (8%)

Query: 103 VEGYSSPIVALRREMGLFANVRPVKSVEGSRNKPIDMVIV-RENTEDLYIKIEKTYIDKA 161
           V  +  PI+  R   G   +      +E   NK I ++I  + + ED  I    ++ +  
Sbjct: 121 VSNWEKPIIIGRHAYG---DQYKATDLEIPPNKDIKLLIQDKADKEDSKIINVFSFPNDG 177

Query: 162 TGTRVADATKRISEIATRRIATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREIC 221
           TG         +  I  +  A  +  +ALKR     +  L +  K+ +L + DG F+ I 
Sbjct: 178 TGGIAMVMYNTVDSI--KGFAKASFIMALKR-----KLPLFLATKNTILKKYDGRFKSIF 230

Query: 222 KEVYESN-KDKYGQI--KYNEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVG 278
            ++Y++  K+K+ ++   Y  +++D MV ++ +    F +I   N  GD+ SD  A   G
Sbjct: 231 DDMYQNEFKEKFEKLGLTYEHRLIDDMVAQMLKSKGGF-IIAMKNYDGDVQSDIVAQGFG 289

Query: 279 SLGVVPSANVGPE--IVIGEPCHGS 301
           SLG++ S  + P+      E  HG+
Sbjct: 290 SLGLMTSQLITPDGKTFQSEAAHGT 314

>NCAS0A02510 Chr1 complement(476363..477643) [1281 bp, 426 aa] {ON}
           Anc_4.254
          Length = 426

 Score = 50.4 bits (119), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 32/106 (30%), Positives = 57/106 (53%), Gaps = 6/106 (5%)

Query: 201 LTVTHKSNVLSQTDGLFREICKEVYESN-KDKYGQ--IKYNEQIVDSMVYRLFREPQCFD 257
           L ++ K+ +L + DG F++I +E+++   K K+    I Y  +++D MV ++ +    F 
Sbjct: 222 LFLSTKNTILKKYDGRFKDIFQEIFDMEYKTKFANLGISYEHRLIDDMVAQMIKSKGGF- 280

Query: 258 VIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIGEPCHGS 301
           ++   N  GD+ SD  A   GSLG++ S  V P+      E  HG+
Sbjct: 281 IMALKNYDGDVQSDIVAQGFGSLGLMTSILVTPDGKTFESEAAHGT 326

>Skud_14.318 Chr14 (581597..582859) [1263 bp, 420 aa] {ON} YNL009W
           (REAL)
          Length = 420

 Score = 50.4 bits (119), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 36/126 (28%), Positives = 63/126 (50%), Gaps = 11/126 (8%)

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESN-KDKYGQ--IKY 237
            A  + ++ALKR        L  T K+ +L   D  F+EI  +++++  K+K+    I Y
Sbjct: 192 FAKASFELALKR-----RLPLFFTTKNTILKSYDNQFKEIFDKLFDAEYKEKFQALGITY 246

Query: 238 NEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIG 295
             +++D MV ++ +    F ++   N  GD+ SD  A   GSLG++ S  + P+      
Sbjct: 247 EHRLIDDMVAQMLKSRGGF-IVAMKNYDGDVQSDIVAQGFGSLGLMTSLLITPDAKTFES 305

Query: 296 EPCHGS 301
           E  HG+
Sbjct: 306 EAAHGT 311

>Suva_14.339 Chr14 (594794..596047) [1254 bp, 417 aa] {ON} YNL009W
           (REAL)
          Length = 417

 Score = 50.1 bits (118), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 35/126 (27%), Positives = 62/126 (49%), Gaps = 11/126 (8%)

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQ---IKY 237
            A  + ++ALKR     +  L  T K+ +L   D  F++I  +++++   +  Q   I Y
Sbjct: 192 FAKASFELALKR-----KLPLFFTTKNTILKNYDNQFKQIFDKLFDAEYKEQFQALGITY 246

Query: 238 NEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIG 295
             +++D MV ++ +    F +I   N  GD+ SD  A   GSLG++ S  + P+      
Sbjct: 247 EHRLIDDMVAQMLKSKGGF-IIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKTFES 305

Query: 296 EPCHGS 301
           E  HG+
Sbjct: 306 EAAHGT 311

>Skud_12.239 Chr12 (451342..452580) [1239 bp, 412 aa] {ON} YLR174W
           (REAL)
          Length = 412

 Score = 49.7 bits (117), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 35/126 (27%), Positives = 65/126 (51%), Gaps = 11/126 (8%)

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESN-KDKYGQ--IKY 237
            A  + ++A++R     +  L  T K+ +L + DG F+++ + +Y  N K+K+    I Y
Sbjct: 192 FAKASFELAIER-----KLPLYSTTKNTILKKYDGKFKDVFEAMYAENYKEKFESLGIWY 246

Query: 238 NEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIG 295
             +++D MV ++ +    + +I   N  GD+ SD  A   GSLG++ S  + P+      
Sbjct: 247 EHRLIDDMVAQMLKSKGGY-IIAMKNYDGDVESDIVAQGFGSLGLMTSMLITPDGKTFES 305

Query: 296 EPCHGS 301
           E  HG+
Sbjct: 306 EAAHGT 311

>Kwal_0.191 s0 (98033..99268) [1236 bp, 411 aa] {ON} YLR174W (IDP2)
           - Cytosolic form of NADP-dependent isocitrate
           dehydrogenase [contig 82] FULL
          Length = 411

 Score = 49.7 bits (117), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 37/127 (29%), Positives = 64/127 (50%), Gaps = 13/127 (10%)

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVY----ESNKDKYGQIK 236
            A  + ++AL+R        L  T K+ +L + DG F+++ + +Y    +S  ++ G I 
Sbjct: 192 FARASFELALQR-----RMPLYSTTKNTILKKYDGKFKDVFEAMYAAEYQSRFEELG-IW 245

Query: 237 YNEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVI 294
           Y  +++D MV ++ +    F +I   N  GD+ SD  A   GSLG++ S  V P+     
Sbjct: 246 YEHRLIDDMVAQMLKSTGGF-IIAMKNYDGDVQSDIVAQGFGSLGLMTSVLVTPDGKTFE 304

Query: 295 GEPCHGS 301
            E  HG+
Sbjct: 305 SEAAHGT 311

>TBLA0A08010 Chr1 (1981576..1982862) [1287 bp, 428 aa] {ON}
           Anc_4.254 YDL066W
          Length = 428

 Score = 49.7 bits (117), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 31/106 (29%), Positives = 55/106 (51%), Gaps = 6/106 (5%)

Query: 201 LTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQ---IKYNEQIVDSMVYRLFREPQCFD 257
           L +  K+ +L + DG F++I +E+YE+   K  +   I Y  +++D MV ++ +    + 
Sbjct: 222 LFLATKNTILKKYDGRFKDIFQEIYENEYKKEFERLNITYEHRLIDDMVAQMIKSKGGY- 280

Query: 258 VIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIGEPCHGS 301
           ++   N  GD+ SD  A   GSLG++ S    P+      E  HG+
Sbjct: 281 IMALKNYDGDVQSDIVAQGFGSLGLMTSILASPDGKTFESEAAHGT 326

>YLR174W Chr12 (504591..505829) [1239 bp, 412 aa] {ON}
           IDP2Cytosolic NADP-specific isocitrate dehydrogenase,
           catalyzes oxidation of isocitrate to
           alpha-ketoglutarate; levels are elevated during growth
           on non-fermentable carbon sources and reduced during
           growth on glucose
          Length = 412

 Score = 49.3 bits (116), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 58/218 (26%), Positives = 100/218 (45%), Gaps = 33/218 (15%)

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVY-ESNKDKYGQ--IKY 237
            A  + ++A++R     +  L  T K+ +L + DG F+++ + +Y  S K+K+    I Y
Sbjct: 192 FAKASFELAIER-----KLPLYSTTKNTILKKYDGKFKDVFEAMYARSYKEKFESLGIWY 246

Query: 238 NEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIG 295
             +++D MV ++ +    + +I   N  GD+ SD  A   GSLG++ S  + P+      
Sbjct: 247 EHRLIDDMVAQMLKSKGGY-IIAMKNYDGDVESDIVAQGFGSLGLMTSVLITPDGKTFES 305

Query: 296 EPCHGSA-----PDIAGKGIA-NPIATIRSTALMLEFLGHNGAAQDIYK-------AVDA 342
           E  HG+          GK  + N IA+I +    +   G      D+ K       A   
Sbjct: 306 EAAHGTVTRHFRQHQQGKETSTNSIASIFAWTRGIIQRGKLDNTPDVVKFGQILESATVN 365

Query: 343 NLREGAITTPDLG---GKA------STQQVVDDVLSRL 371
            ++E  I T DL    GK+      +T++ +D V SRL
Sbjct: 366 TVQEDGIMTKDLALILGKSERSAYVTTEEFIDAVESRL 403

>Suva_10.271 Chr10 (476726..477964) [1239 bp, 412 aa] {ON} YLR174W
           (REAL)
          Length = 412

 Score = 48.9 bits (115), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 36/126 (28%), Positives = 65/126 (51%), Gaps = 11/126 (8%)

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVY-ESNKDKYGQ--IKY 237
            A  + ++AL+R     +  L  T K+ +L + DG F+++ + +Y E  K+K+    I Y
Sbjct: 192 FAKASFELALER-----KLPLYSTTKNTILKKYDGKFKDVFEAMYAEVYKEKFEALGIWY 246

Query: 238 NEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIG 295
             +++D MV ++ +    + +I   N  GD+ SD  A   GSLG++ S  + P+      
Sbjct: 247 EHRLIDDMVAQMLKSKGGY-IIAMKNYDGDVESDIVAQGFGSLGLMTSLLITPDGKTFES 305

Query: 296 EPCHGS 301
           E  HG+
Sbjct: 306 EAAHGT 311

>KLLA0F12342g Chr6 (1137608..1138855) [1248 bp, 415 aa] {ON} highly
           similar to uniprot|P41939 Saccharomyces cerevisiae
           YLR174W IDP2 Cytosolic NADP-specific isocitrate
           dehydrogenase catalyzes oxidation of isocitrate to
           alpha- ketoglutarate levels are elevated during growth
           on non- fermentable carbon sources and reduced during
           growth on glucose
          Length = 415

 Score = 48.9 bits (115), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 31/106 (29%), Positives = 54/106 (50%), Gaps = 6/106 (5%)

Query: 201 LTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQ---IKYNEQIVDSMVYRLFREPQCFD 257
           L  T K+ +L + DG F+++ + +YES      +   I Y  +++D MV ++ +    + 
Sbjct: 210 LYSTTKNTILKKYDGKFKDVFESLYESQYKSAFEAKGIWYEHRLIDDMVAQMLKSKGGY- 268

Query: 258 VIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIGEPCHGS 301
           +I   N  GD+ SD  A   GSLG++ S  + P+      E  HG+
Sbjct: 269 IIAMKNYDGDVESDIVAQGFGSLGLMTSVLITPDGKAFESEAAHGT 314

>ZYRO0B12496g Chr2 complement(1007086..1008354) [1269 bp, 422 aa]
           {ON} highly similar to uniprot|P21954 Saccharomyces
           cerevisiae YDL066W IDP1 Mitochondrial NADP-specific
           isocitrate dehydrogenase catalyzes the oxidation of
           isocitrate to alpha-ketoglutarate not required for
           mitochondrial respiration and may function to divert
           alpha- ketoglutarate to biosynthetic processes
          Length = 422

 Score = 48.9 bits (115), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 32/107 (29%), Positives = 58/107 (54%), Gaps = 8/107 (7%)

Query: 201 LTVTHKSNVLSQTDGLFREICKEVYESNK----DKYGQIKYNEQIVDSMVYRLFREPQCF 256
           L ++ K+ +L + DG F++I +E+Y++      +K G I Y  +++D MV ++ +    F
Sbjct: 218 LYLSTKNTILKKYDGRFKDIFQELYDTQYKAEFEKAG-IFYEHRLIDDMVAQMVKSKGGF 276

Query: 257 DVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIGEPCHGS 301
            ++   N  GD+ SD  A   GSLG++ S  + P+      E  HG+
Sbjct: 277 -IMALKNYDGDVQSDIVAQGFGSLGLMTSVLITPDGKTFESEAAHGT 322

>TPHA0B03660 Chr2 (863280..864548) [1269 bp, 422 aa] {ON} Anc_1.396
           YLR174W
          Length = 422

 Score = 48.1 bits (113), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 36/126 (28%), Positives = 63/126 (50%), Gaps = 11/126 (8%)

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVY-ESNKDKYG--QIKY 237
            A  + + AL+R     +  L  T K+ +L + DG F++I + +Y E  ++K+    I Y
Sbjct: 203 FARSSFEFALER-----KLPLYSTTKNTILKKYDGQFKDIFESMYKEEYEEKFKALNIWY 257

Query: 238 NEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIG 295
             +++D MV ++ +    F +I   N  GD+ SD  A   GSLG++ S  +  +      
Sbjct: 258 EHRLIDDMVAQMLKSKGGF-IIAMKNYDGDVQSDIVAQGFGSLGLMTSVLISDDGKTFES 316

Query: 296 EPCHGS 301
           E  HG+
Sbjct: 317 EAAHGT 322

>Ecym_3265 Chr3 (504267..505541) [1275 bp, 424 aa] {ON} similar to
           Ashbya gossypii AER061C
          Length = 424

 Score = 47.0 bits (110), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 31/107 (28%), Positives = 56/107 (52%), Gaps = 8/107 (7%)

Query: 201 LTVTHKSNVLSQTDGLFREICKEVYESNK----DKYGQIKYNEQIVDSMVYRLFREPQCF 256
           L ++ K+ +L   DG F++I +E+Y++      + +G I Y  +++D MV ++ +    F
Sbjct: 220 LFLSTKNTILKTYDGRFKDIFQELYDTQYKTEFENHG-IYYEHRLIDDMVAQMIKSKGGF 278

Query: 257 DVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIGEPCHGS 301
            ++   N  GD+ SD  A   GSLG++ S    P+      E  HG+
Sbjct: 279 -IMALKNYDGDVQSDIVAQGFGSLGLMTSILATPDGKTFESEAAHGT 324

>Suva_14.303 Chr14 (547367..547525) [159 bp, 53 aa] {ON} YNL037C
           (REAL)
          Length = 53

 Score = 40.4 bits (93), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 21/50 (42%), Positives = 31/50 (62%)

Query: 322 LMLEFLGHNGAAQDIYKAVDANLREGAITTPDLGGKASTQQVVDDVLSRL 371
           LML  LG N +A  I KAV   + EG  TT D+GG +ST    ++++++L
Sbjct: 1   LMLNHLGLNESATRISKAVHETIAEGKHTTRDIGGSSSTTDFTNEIINKL 50

>NDAI0G05160 Chr7 complement(1250883..1252145) [1263 bp, 420 aa]
           {ON} Anc_1.396
          Length = 420

 Score = 42.7 bits (99), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 35/126 (27%), Positives = 61/126 (48%), Gaps = 11/126 (8%)

Query: 181 IATIALDIALKRLQTRGEATLTVTHKSNVLSQTDGLFREICKEVYESNKDKYGQ---IKY 237
            A  +  +AL+R     +  L  T K+ +L + DG F++I + +YE    +  +   I Y
Sbjct: 200 FALSSFKLALER-----KMPLYSTTKNTILKRYDGKFKDIFENMYEEQFREQFEELGIWY 254

Query: 238 NEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIG 295
             +++D MV ++ +    F +I   N  GD+ SD  A   GSLG++ S  +  +      
Sbjct: 255 EHRLIDDMVAQMLKSKGGF-IIAMKNYDGDVQSDIVAQGFGSLGLMTSVLISSDGKSFES 313

Query: 296 EPCHGS 301
           E  HG+
Sbjct: 314 EAAHGT 319

>NCAS0F03500 Chr6 complement(700666..702330) [1665 bp, 554 aa] {ON} 
          Length = 554

 Score = 32.7 bits (73), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 20/55 (36%), Positives = 30/55 (54%), Gaps = 5/55 (9%)

Query: 178 TRRIATIALDIALKRLQTRGEATLTVTHKSN-VLSQTDGLFREICKEVYESNKDK 231
           T R   ++L    K+L +RG+ TL V+ K+   L Q    F++ C+  YES K K
Sbjct: 50  TYRFLVVSLFQIFKKLFSRGDLTLRVSDKTTPELKQ----FKQWCRRTYESFKTK 100

>KNAG0A03750 Chr1 (487451..489943) [2493 bp, 830 aa] {ON} Anc_8.531
           YBR202W
          Length = 830

 Score = 32.3 bits (72), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 19/65 (29%), Positives = 34/65 (52%)

Query: 141 IVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALKRLQTRGEAT 200
           +VR + E LY    KT  D+   TR+ +  KR+S+       T++ D  +K +++RG   
Sbjct: 722 LVRVSKESLYQDNTKTREDQNPTTRIYNLIKRMSQDTLENRGTLSYDTIVKTVRSRGFTM 781

Query: 201 LTVTH 205
           L + +
Sbjct: 782 LQLNN 786

>Ecym_8110 Chr8 (234106..235344) [1239 bp, 412 aa] {ON} similar to
          Ashbya gossypii AEL130C
          Length = 412

 Score = 31.2 bits (69), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 7/72 (9%)

Query: 15 LATNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFIDLYAGFQTFQETGK 74
          +AT  A + L +G +     G+ V+P   Q+    NSK   + +F+++  GF     TG 
Sbjct: 4  IATALASQVLLLGTVKSVDNGESVLPVKSQIFNTENSKLCQAIDFVNV--GF-----TGS 56

Query: 75 ALPDETVNVLKK 86
           LP  ++N ++K
Sbjct: 57 YLPVSSLNDIEK 68

  Database: Seq/AA.fsa
    Posted date:  Aug 24, 2012  3:22 PM
  Number of letters in database: 53,481,399
  Number of sequences in database:  114,666
  
Lambda     K      H
   0.317    0.134    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 114666
Number of Hits to DB: 34,865,437
Number of extensions: 1439639
Number of successful extensions: 4217
Number of sequences better than 10.0: 142
Number of HSP's gapped: 3982
Number of HSP's successfully gapped: 142
Length of query: 371
Length of database: 53,481,399
Length adjustment: 111
Effective length of query: 260
Effective length of database: 40,753,473
Effective search space: 10595902980
Effective search space used: 10595902980
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)