Gene Ontology (GO) Terms in Locus Classes

ClassRatio of Term in Class% ClassGO TermRatio of Term in Genome% GenomeP-value*
0(24/210)11.43%Kinase activity(122.5/2723)4.50%0.0003019228
0(18/210)8.57%Protein kinase activity(88.5/2723)3.25%0.0009975473
0(13/210)6.19%Protein serine/threonine kinase activity(56/2723)2.06%0.001353231
0(15/210)7.14%Response to drug(71.5/2723)2.63%0.001570295
0(25/210)11.90%Carbohydrate metabolism(149.5/2723)5.49%0.001657241
0(16/210)7.62%Transcription factor activity(77.5/2723)2.85%0.001906076
0(19.5/210)9.29%Phosphate metabolism(119/2723)4.37%0.00734047
0(9.5/210)4.52%Carbohydrate biosynthesis(39.5/2723)1.45%0.008184801
0(16.5/210)7.86%Phosphorylation(93.5/2723)3.43%0.0081987
0(5/210)2.38%Cyclin-dependent protein kinase, regulator activity(14/2723)0.51%0.009870484
0(22.5/210)10.71%Cellular morphogenesis(149/2723)5.47%0.01024425
0(15/210)7.14%Protein amino acid phosphorylation(87/2723)3.20%0.01052995
0(29/210)13.81%Transcription regulator activity(216.5/2723)7.95%0.01166270
0(7.5/210)3.57%Metal ion transport(28/2723)1.03%0.01180234
0(8.5/210)4.05%Protein localization(36/2723)1.32%0.01306002
0(18.5/210)8.81%Cell wall organization and biogenesis(120/2723)4.41%0.01848046
0(18/210)8.57%Signal transduction(122.5/2723)4.50%0.02026004
0(6.5/210)3.10%Glucose metabolism(25.5/2723)0.94%0.02602050
0(3/210)1.43%Structural constituent of cell wall(7/2723)0.26%0.03140796
0(5.5/210)2.62%Enzyme inhibitor activity(19.5/2723)0.72%0.03178749
0(5/210)2.38%Carbohydrate catabolism(21/2723)0.77%0.03713372
0(6.5/210)3.10%Kinase regulator activity(28.5/2723)1.05%0.03892537
0(6.5/210)3.10%Invasive growth(29.5/2723)1.08%0.04403117
0(38/210)18.10%Response to stress(337.5/2723)12.39%0.04924421
* Fishers Exact Test Two Tail with Benjamini and Hochberg False Discovery Rate Correction for Multiple Testing

ClassRatio of Term in Class% ClassGO TermRatio of Term in Genome% GenomeP-value*
1A(3/33)9.09%Lyase activity(43.5/2723)1.60%0.02181516
* Fishers Exact Test Two Tail with Benjamini and Hochberg False Discovery Rate Correction for Multiple Testing

ClassRatio of Term in Class% ClassGO TermRatio of Term in Genome% GenomeP-value*
1B(4/18)22.22%Transcriptional activator activity(58/2723)2.13%0.001180972
1B(8/18)44.44%DNA binding activity(256.5/2723)9.42%0.001258077
1B(7/18)38.89%Transcription regulator activity(216.5/2723)7.95%0.001899603
1B(4/18)22.22%Transcription factor activity(77.5/2723)2.85%0.003264378
1B(2/18)11.11%Mating-type determination(18/2723)0.66%0.008841317
1B(3/18)16.67%RNA polymerase II transcription factor activity(70.5/2723)2.59%0.01673971
1B(4/18)22.22%Budding(131.5/2723)4.83%0.01825018
1B(5/18)27.78%Regulation of transcription from Pol II promoter(204/2723)7.49%0.02031332
1B(6/18)33.33%Transcription from Pol II promoter(277.5/2723)10.19%0.02077900
1B(8/18)44.44%Transcription, DNA-dependent(435/2723)15.98%0.02115941
1B(6/18)33.33%Regulation of transcription, DNA-dependent(284/2723)10.43%0.02267404
1B(3/18)16.67%Conjugation with cellular fusion(92.5/2723)3.40%0.03289662
1B(3/18)16.67%DNA recombination(94.5/2723)3.47%0.034643
1B(2/18)11.11%Mitotic recombination(41.5/2723)1.52%0.03978037
1B(2/18)11.11%Transcriptional repressor activity(42/2723)1.54%0.03979037
1B(6/18)33.33%Response to stress(337.5/2723)12.39%0.04482505
1B(12/18)66.67%Nucleobase, nucleoside, nucleotide and nucleic acid metabolism(809/2723)29.71%0.04793574
1B(2/18)11.11%RNA localization(46.5/2723)1.71%0.0485210
* Fishers Exact Test Two Tail with Benjamini and Hochberg False Discovery Rate Correction for Multiple Testing

ClassRatio of Term in Class% ClassGO TermRatio of Term in Genome% GenomeP-value*
1C(33/98)33.67%Structural constituent of ribosome(99/2723)3.64%0.0000000000
1C(34/98)34.69%Structural molecule activity(171/2723)6.28%0.0000000000
1C(35/98)35.71%Protein biosynthesis(270/2723)9.92%0.0000000155
1C(33.5/98)34.18%RNA binding activity(298.5/2723)10.96%0.0000011609
1C(0.5/98)0.51%Nucleotide binding activity(195.5/2723)7.18%0.02042767
1C(3/98)3.06%Protein serine/threonine phosphatase activity(13.5/2723)0.50%0.02104194
1C(0/98)0.00%ATPase activity(130/2723)4.77%0.02156450
1C(0/98)0.00%ATP binding activity(136.5/2723)5.01%0.02289903
1C(23/98)23.47%Molecular_function unknown(1015/2723)37.28%0.04949949
* Fishers Exact Test Two Tail with Benjamini and Hochberg False Discovery Rate Correction for Multiple Testing

ClassRatio of Term in Class% ClassGO TermRatio of Term in Genome% GenomeP-value*
2A(4/15)26.67%Amino acid biosynthesis(74/2723)2.72%0.001544299
2A(4/15)26.67%Amino acid metabolism(117.5/2723)4.32%0.007481854
2A(3/15)20.00%Cell ion homeostasis(63.5/2723)2.33%0.008296315
2A(3/15)20.00%Aerobic respiration(88/2723)3.23%0.01879276
2A(2/15)13.33%Metal ion homeostasis(32.5/2723)1.19%0.01898122
2A(3/15)20.00%Structural constituent of ribosome(99/2723)3.64%0.02530976
2A(4/15)26.67%Organic acid metabolism(179.5/2723)6.59%0.02859496
2A(3/15)20.00%Kinase activity(122.5/2723)4.50%0.04307419
2A(5/15)33.33%Protein modification(301/2723)11.05%0.04481100
* Fishers Exact Test Two Tail with Benjamini and Hochberg False Discovery Rate Correction for Multiple Testing

ClassRatio of Term in Class% ClassGO TermRatio of Term in Genome% GenomeP-value*
2B(8/86)9.30%Transcriptional activator activity(58/2723)2.13%0.001169329
2B(8/86)9.30%Intracellular signaling cascade(61.5/2723)2.26%0.001714328
2B(10/86)11.63%Signal transduction(122.5/2723)4.50%0.01043576
2B(5/86)5.81%Membrane fusion(38/2723)1.40%0.01106607
2B(3/86)3.49%Small monomeric GTPase activity(14/2723)0.51%0.01510777
2B(9/86)10.47%Biological_process unknown(654/2723)24.02%0.01655370
2B(3/86)3.49%Tubulin binding activity(17/2723)0.62%0.02376991
2B(10/86)11.63%Protein catabolism(142/2723)5.21%0.03014308
2B(2/86)2.33%Carbohydrate transport(7/2723)0.26%0.03081065
2B(10/86)11.63%Carbohydrate metabolism(149.5/2723)5.49%0.03729369
2B(7/86)8.14%Conjugation with cellular fusion(92.5/2723)3.40%0.03991940
2B(12/86)13.95%Vesicle-mediated transport(193/2723)7.09%0.04039246
2B(6/86)6.98%Lipid biosynthesis(75.5/2723)2.77%0.04579421
2B(9/86)10.47%Budding(131.5/2723)4.83%0.04586231
2B(5/86)5.81%Response to pheromone(58/2723)2.13%0.04904696
* Fishers Exact Test Two Tail with Benjamini and Hochberg False Discovery Rate Correction for Multiple Testing

ClassRatio of Term in Class% ClassGO TermRatio of Term in Genome% GenomeP-value*
2C(2/12)16.67%Guanyl nucleotide binding activity(57.5/2723)2.11%0.03584873
* Fishers Exact Test Two Tail with Benjamini and Hochberg False Discovery Rate Correction for Multiple Testing

ClassRatio of Term in Class% ClassGO TermRatio of Term in Genome% GenomeP-value*
2D(2/38)5.26%Small monomeric GTPase activity(14/2723)0.51%0.02175669
2D(5.5/38)14.47%Oxidoreductase activity(116/2723)4.26%0.03305999
* Fishers Exact Test Two Tail with Benjamini and Hochberg False Discovery Rate Correction for Multiple Testing

ClassRatio of Term in Class% ClassGO TermRatio of Term in Genome% GenomeP-value*
2E(1/9)11.11%Amine/polyamine transporter activity(6/2723)0.22%0.02584979
2E(1/9)11.11%Flocculation(10.5/2723)0.39%0.04424913
* Fishers Exact Test Two Tail with Benjamini and Hochberg False Discovery Rate Correction for Multiple Testing

ClassRatio of Term in Class% ClassGO TermRatio of Term in Genome% GenomeP-value*
2F(8/28)28.57%Nuclear organization and biogenesis(198.5/2723)7.29%0.002764243
2F(6/28)21.43%Chromatin modification(118.5/2723)4.35%0.00296578
2F(3/28)10.71%Chromatin binding activity(23.5/2723)0.86%0.003087855
2F(3/28)10.71%Glucose metabolism(25.5/2723)0.94%0.003793825
2F(2/28)7.14%Glycolysis(7/2723)0.26%0.003946533
2F(5/28)17.86%Chromatin modeling(93/2723)3.42%0.00483044
2F(6/28)21.43%Establishment and/or maintenance of chromatin architecture(137.5/2723)5.05%0.005818135
2F(2/28)7.14%Carbohydrate kinase activity(8.5/2723)0.31%0.005947410
2F(8/28)28.57%DNA binding activity(256.5/2723)9.42%0.01110253
2F(3/28)10.71%Monosaccharide metabolism(45.5/2723)1.67%0.01627033
2F(1/28)3.57%Permease activity(1/2723)0.04%0.02132592
2F(2/28)7.14%Carbohydrate catabolism(21/2723)0.77%0.02537763
2F(6/28)21.43%Regulation of transcription from Pol II promoter(204/2723)7.49%0.03053449
2F(7/28)25.00%Transcription from Pol II promoter(277.5/2723)10.19%0.04164072
2F(2/28)7.14%Heavy metal binding activity(28.5/2723)1.05%0.04439343
2F(2/28)7.14%Isomerase activity(30/2723)1.10%0.04710518
* Fishers Exact Test Two Tail with Benjamini and Hochberg False Discovery Rate Correction for Multiple Testing

ClassRatio of Term in Class% ClassGO TermRatio of Term in Genome% GenomeP-value*
3A(12/134)8.96%Transcription from Pol I promoter(76.5/2723)2.81%0.001217642
3A(6/134)4.48%Ribonuclease activity(26.5/2723)0.97%0.004375919
3A(9/134)6.72%rRNA processing(59.5/2723)2.19%0.005728802
3A(6/134)4.48%tRNA binding activity(31/2723)1.14%0.007794253
3A(5/134)3.73%Structural constituent of cytoskeleton(23/2723)0.84%0.00977319
3A(4/134)2.99%Actin binding activity(15.5/2723)0.57%0.01364448
3A(26/134)19.40%RNA binding activity(298.5/2723)10.96%0.01525617
3A(4/134)2.99%RNA ligase activity(21/2723)0.77%0.02973713
3A(4/134)2.99%tRNA ligase activity(21/2723)0.77%0.02974457
3A(20/134)14.93%RNA processing(228/2723)8.37%0.03165878
3A(23/134)17.16%RNA metabolism(278/2723)10.21%0.03598592
3A(6/134)4.48%Regulation of transcription, DNA-dependent(284/2723)10.43%0.03700997
3A(27/134)20.15%Hydrolase activity(339.5/2723)12.47%0.04151970
3A(9/134)6.72%Ribosome biogenesis(82/2723)3.01%0.04160543
3A(6/134)4.48%Nuclease activity(48.5/2723)1.78%0.04779065
* Fishers Exact Test Two Tail with Benjamini and Hochberg False Discovery Rate Correction for Multiple Testing

ClassRatio of Term in Class% ClassGO TermRatio of Term in Genome% GenomeP-value*
3B(2/33)6.06%Transcription co-repressor activity(13.5/2723)0.50%0.01687550
3B(3/33)9.09%Regulation of translation(44.5/2723)1.63%0.02306279
3B(3/33)9.09%Transcription cofactor activity(44.5/2723)1.63%0.02306854
3B(2/33)6.06%Hydrogen-transporting two-sector ATPase activity(17/2723)0.62%0.02355504
3B(2/33)6.06%Monovalent inorganic cation transporter activity(17/2723)0.62%0.02356091
3B(2/33)6.06%Hydrogen-/sodium-translocating ATPase activity(17/2723)0.62%0.02356679
3B(2/33)6.06%Hydrogen ion transporter activity(17/2723)0.62%0.02357267
3B(4/33)12.12%Ribosome biogenesis(82/2723)3.01%0.02462681
3B(2/33)6.06%Hydrogen transport(23.5/2723)0.86%0.0425977
3B(3/33)9.09%rRNA processing(59.5/2723)2.19%0.04644672
* Fishers Exact Test Two Tail with Benjamini and Hochberg False Discovery Rate Correction for Multiple Testing

ClassRatio of Term in Class% ClassGO TermRatio of Term in Genome% GenomeP-value*
3C(8/52)15.38%rRNA processing(59.5/2723)2.19%0.0000671770
3C(8/52)15.38%Transcription from Pol I promoter(76.5/2723)2.81%0.0003173696
3C(8/52)15.38%Ribosome biogenesis(82/2723)3.01%0.0004655319
3C(3/52)5.77%tRNA ligase activity(21/2723)0.77%0.01096918
3C(3/52)5.77%RNA ligase activity(21/2723)0.77%0.01097190
3C(4/52)7.69%Lyase activity(43.5/2723)1.60%0.01432652
3C(5/52)9.62%Amino acid biosynthesis(74/2723)2.72%0.01976364
3C(10/52)19.23%RNA processing(228/2723)8.37%0.02798703
3C(3/52)5.77%tRNA binding activity(31/2723)1.14%0.02830996
3C(2/52)3.85%Guanyl-nucleotide exchange factor activity(13.5/2723)0.50%0.03808268
3C(4/52)7.69%Ligase activity(64/2723)2.35%0.04464350
3C(11/52)21.15%RNA metabolism(278/2723)10.21%0.04657850
* Fishers Exact Test Two Tail with Benjamini and Hochberg False Discovery Rate Correction for Multiple Testing

ClassRatio of Term in Class% ClassGO TermRatio of Term in Genome% GenomeP-value*
4(44/1957)2.25%Structural constituent of ribosome(99/2723)3.64%0.009607444
4(93/1957)4.75%Structural molecule activity(171/2723)6.28%0.03517732
* Fishers Exact Test Two Tail with Benjamini and Hochberg False Discovery Rate Correction for Multiple Testing

Yeast Gene Ontology (GO) data was downloaded in April 2003 from Incyte's Yeast Proteome Database (YPD) website.

© 2006 - Kevin Byrne - Wolfe Laboratory - University College Dublin